日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An active allosteric mechanism in ASAP1-mediated Arf1 GTP hydrolysis redefines PH domain function

ASAP1介导的Arf1 GTP水解中的活性变构机制重新定义了PH结构域的功能

Soubias, Olivier; Foley, Samuel L; Jian, Xiaoying; Jackson, Rebekah A; Zhang, Yue; Rosenberg, Eric M Jr; Hu, Benjamin J; Li, Jess; Heinrich, Frank; Johnson, Margaret E; Sodt, Alexander J; Randazzo, Paul A; Byrd, R Andrew

ARF: the most misunderstood GTPase I ever knew - why study ARF GAPs

ARF:我所知的最被误解的GTP酶——为什么要研究ARF GAPs

Turn, Rachel E; Dacks, Joel Bryan; Rosenberg, Eric M Jr; Soubias, Olivier; Northup, John K; Randazzo, Paul A

Solid-state NMR of membrane peptides and proteins in the lipid cubic phase.

脂质立方相中膜肽和蛋白质的固态核磁共振

Ramberg Kiefer O, Boland Coilin, Kooshapur Hamed, Soubias Olivier, Wiktor Maciej, Huang Chia-Ying, Bailey Jonathan, Gawrisch Klaus, Caffrey Martin

Small angle neutron scattering study of rhodopsin oligomerization and G-protein coupling in a physiologically relevant lipid membrane

利用小角中子散射技术研究生理相关脂质膜中视紫红质寡聚化和G蛋白偶联的情况

Soubias, Olivier; Nickels, Jonathan D; Hines, Kirk G; Teague, Walter E; Northup, John K; Katsaras, John; Gawrisch, Klaus

The PH domain in the ArfGAP ASAP1 drives catalytic activation through an unprecedented allosteric mechanism

ArfGAP ASAP1 中的 PH 结构域通过一种前所未有的变构机制驱动催化活化。

Soubias, Olivier; Foley, Samuel L; Jian, Xiaoying; Jackson, Rebekah A; Zhang, Yue; Rosenberg, Eric M Jr; Li, Jess; Heinrich, Frank; Johnson, Margaret E; Sodt, Alexander J; Randazzo, Paul A; Byrd, R Andrew

Redefining PH Domain Function: An Active Allosteric Mechanism in ASAP1-Mediated Arf1 GTP Hydrolysis

重新定义PH结构域功能:ASAP1介导的Arf1 GTP水解中的活性变构机制

Randazzo, Paul; Soubias, Olivier; Foley, Samuel; Jian, Xiaoying; Jackson, Rebekah; Zhang, Yue; Rosenberg, Eric; Li, Jess; Heinrich, Frank; Johnson, Margaret; Sodt, Alexander; Byrd, R Andrew; Hu, Benjamin

Point mutations in Arf1 reveal cooperative effects of the N-terminal extension and myristate for GTPase-activating protein catalytic activity

Arf1 中的点突变揭示了 N 端延伸和肉豆蔻酸对 GTP 酶激活蛋白催化活性的协同作用

Rosenberg, Eric M Jr; Jian, Xiaoying; Soubias, Olivier; Jackson, Rebekah A; Gladu, Erin; Andersen, Emily; Esser, Lothar; Sodt, Alexander J; Xia, Di; Byrd, R Andrew; Randazzo, Paul A

Myr-Arf1 conformational flexibility at the membrane surface sheds light on the interactions with ArfGAP ASAP1

膜表面的 Myr-Arf1 构象灵活性揭示了与 ArfGAP ASAP1 的相互作用

Yue Zhang #, Olivier Soubias #, Shashank Pant #, Frank Heinrich, Alexander Vogel, Jess Li, Yifei Li, Luke A Clifton, Sebastian Daum, Kirsten Bacia, Daniel Huster, Paul A Randazzo, Mathias Lösche, Emad Tajkhorshid, R Andrew Byrd

The small molecule inhibitor NAV-2729 has a complex target profile including multiple ADP-ribosylation factor regulatory proteins

小分子抑制剂 NAV-2729 具有复杂的靶标特征,包括多个 ADP 核糖基化因子调节蛋白

Eric M Rosenberg Jr, Xiaoying Jian, Olivier Soubias, Hye-Young Yoon, Mukesh P Yadav, Sarah Hammoudeh, Sandeep Pallikkuth, Itoro Akpan, Pei-Wen Chen, Tapan K Maity, Lisa M Jenkins, Marielle E Yohe, R Andrew Byrd, Paul A Randazzo

Special issue for Klaus Gawrisch

克劳斯·加夫里施特刊

Zimmerberg, Joshua; Soubias, Olivier; Pastor, Richard W