日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Systematic analysis of siRNA and mRNA features impacting fully chemically modified siRNA efficacy.

对影响完全化学修饰的siRNA功效的siRNA和mRNA特征进行系统分析

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaf479
Davis Sarah M, Hildebrand Samuel, MacMillan Hannah J, Monopoli Kathryn R, Buchwald Julianna, Sousa Jacquelyn, Cooper David, Ly Socheata, Echeverria Dimas, McHugh Nicholas, Ferguson Chantal, Coles Andrew, Hariharan Vignesh N, O'Reilly Daniel, Tang Qi, Furgal Raymond, Yamada Ken, Alterman Julia F, Gilbert James W, Knox Emily, Pineda Yamilett, Weston Caitlyn N, Baer Christina E, Pai Athma A, Khvorova Anastasia
其它
发表日期：2025
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Quantifying the activity profile of ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo.

量化 ASO 和 siRNA 缀合物在胶质母细胞瘤异种移植瘤体内的活性谱

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkae260
Sarli Samantha L, Fakih Hassan H, Kelly Karen, Devi Gitali, Rembetsy-Brown Julia M, McEachern Holly R, Ferguson Chantal M, Echeverria Dimas, Lee Jonathan, Sousa Jacquelyn, Sleiman Hanadi F, Khvorova Anastasia, Watts Jonathan K
细胞生物学
发表日期：2024
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Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts

气管内注射LNA gapmer反义寡核苷酸可诱导小鼠肺成纤维细胞中强烈的基因沉默。

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkac630
Shin, Minwook; Chan, Io Long; Cao, Yuming; Gruntman, Alisha M; Lee, Jonathan; Sousa, Jacquelyn; Rodríguez, Tomás C; Echeverria, Dimas; Devi, Gitali; Debacker, Alexandre J; Moazami, Michael P; Krishnamurthy, Pranathi Meda; Rembetsy-Brown, Julia M; Kelly, Karen; Yukselen, Onur; Donnard, Elisa; Parsons, Teagan J; Khvorova, Anastasia; Sontheimer, Erik J; Maehr, René; Garber, Manuel; Watts, Jonathan K
成纤维细胞
细胞生物学
表观遗传
发表日期：2022
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The chemical structure and phosphorothioate content of hydrophobically modified siRNAs impact extrahepatic distribution and efficacy.

疏水修饰的siRNA的化学结构和硫代磷酸酯含量会影响肝外分布和疗效

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaa595
Biscans Annabelle, Caiazzi Jillian, Davis Sarah, McHugh Nicholas, Sousa Jacquelyn, Khvorova Anastasia
表观遗传
发表日期：2020
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