Soutto Mohammed相关文献与解析，生知库 | 链接生命科学的每一步

Lu, Heng; Ballout, Farah; Chen, Lei; Peng, Dunfa; Chen, Zheng; Soutto, Mohammed; Cao, Longlong; Thangaretnam, Krishnapriya; Gokulan, Ravindran Caspa; Wang, Timothy C; Que, Jianwen; Giordano, Silvia; Washington, Mary Kay; Chen, Xi Steven; Sun, Xiaodian; Ban, Yuguang; McDonald, Oliver Gene; Zaika, Alexander; El-Rifai, Wael

肿瘤

SOX

肿瘤免疫

SOX9

发表日期：2026

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Enhancing the antitumor efficacy using a combination of FGFR4 Inhibitor (H3B-6527) and oxaliplatin in gastric cancer.

在胃癌治疗中，FGFR4抑制剂（H3B-6527）与奥沙利铂联合应用可增强抗肿瘤疗效。

期刊:Neoplasia

影响因子:7.7

doi:10.1016/j.neo.2025.101257

Bhat Nadeem, Soutto Mohammed, Chen Zheng, Al-Mathkour Marwah, Silvia Giordano, Chwihne Mohammed, Genoula Melanie, Ballout Farah, Zhu Shoumin, McDonald Oliver G, El-Rifai Wael

CDK1 drives SOX9-mediated chemotherapeutic resistance in gastric cancer.

CDK1 驱动 SOX9 介导的胃癌化疗耐药性。

期刊:Journal of Experimental & Clinical Cancer Research

影响因子:12.8

doi:10.1186/s13046-025-03523-3

Al-Mathkour Marwah, Chen Zheng, Poveda Julio, Cao Longlong, McDonald Oliver G, Peng Dunfa, Soutto Mohammed, Chen Zhibin, Lu Heng, Guo Yan, Kumar Shria, Zaika Alexander, Giordano Silvia, Zhu Shoumin, El-Rifai Wael

SOX9 is regulated by AURKA in response to Helicobacter pylori infection via EIF4E-mediated cap-dependent translation

SOX9 受 AURKA 调控，响应幽门螺杆菌感染，其调控机制是通过 EIF4E 介导的帽依赖性翻译。

期刊:Cancer Letters

影响因子:10.1

doi:10.1016/j.canlet.2024.216939

Gomaa, Ahmed; Maacha, Selma; Peng, Dunfa; Soutto, Mohammed; Genoula, Melanie; Bhat, Nadeem; Cao, Longlong; Zhu, Shoumin; Castells, Antoni; Chen, Zhibin; Zaika, Alexander; McDonald, Oliver G; El-Rifai, Wael

Multivalent tyrosine kinase inhibition promotes T cell recruitment to immune-desert gastric cancers by restricting epithelial-mesenchymal transition via tumour-intrinsic IFN-γ signalling

多价酪氨酸激酶抑制剂通过限制肿瘤内在的IFN-γ信号通路介导的上皮-间质转化，促进T细胞募集至免疫沙漠胃癌部位。

期刊:Gut

影响因子:25.8

doi:10.1136/gutjnl-2022-329134

Cao, Long Long; Lu, Heng; Soutto, Mohammed; Bhat, Nadeem; Chen, Zheng; Peng, Dunfa; Gomaa, Ahmed; Wang, Jia Bin; Xie, Jian Wei; Li, Ping; Zheng, Chao Hui; Nomura, Sachiyo; Datta, Jashodeep; Merchant, Nipun; Chen, Zhi Bin; Villarino, Alejandro; Zaika, Alexander; Huang, Chang Ming; El-Rifai, Wael

Reflux conditions induce E-cadherin cleavage and EMT via APE1 redox function in oesophageal adenocarcinoma

反流条件通过APE1氧化还原功能诱导食管腺癌中E-钙黏蛋白裂解和上皮间质转化（EMT）。

期刊:Gut

影响因子:25.8

doi:10.1136/gutjnl-2023-329455

Lu, Heng; Cao, Long Long; Ballout, Farah; Belkhiri, Abbes; Peng, DunFa; Chen, Lei; Chen, Zheng; Soutto, Mohammed; Wang, Timothy C; Que, Jianwen; Giordano, Silvia; Washington, Mary Kay; Chen, Steven; McDonald, Oliver Gene; Zaika, Alexander; El-Rifai, Wael

Helicobacter pylori-induced RASAL2 Through Activation of Nuclear Factor-κB Promotes Gastric Tumorigenesis via β-catenin Signaling Axis

幽门螺杆菌诱导的RASAL2通过激活核因子-κB，经由β-catenin信号通路促进胃肿瘤发生

期刊:Gastroenterology

影响因子:25.1

doi:10.1053/j.gastro.2022.01.046

Cao, Longlong; Zhu, Shoumin; Lu, Heng; Soutto, Mohammed; Bhat, Nadeem; Chen, Zheng; Peng, Dunfa; Lin, Jianxian; Lu, Jun; Li, Ping; Zheng, Chaohui; Huang, Changming; El-Rifai, Wael

Integrated Analysis of Mouse and Human Gastric Neoplasms Identifies Conserved microRNA Networks in Gastric Carcinogenesis

对小鼠和人类胃肿瘤的综合分析揭示了胃癌发生过程中保守的microRNA网络

期刊:Gastroenterology

影响因子:25.1

doi:10.1053/j.gastro.2018.11.052

Chen, Zheng; Li, Zheng; Soutto, Mohammed; Wang, Weizhi; Piazuelo, M Blanca; Zhu, Shoumin; Guo, Yan; Maturana, Maria J; Corvalan, Alejandro H; Chen, Xi; Xu, Zekuan; El-Rifai, Wael M

Helicobacter pylori-induced miR-135b-5p promotes cisplatin resistance in gastric cancer

幽门螺杆菌诱导的miR-135b-5p促进胃癌对顺铂的耐药性

期刊:FASEB Journal

影响因子:4.2

doi:10.1096/fj.201701456RR

Shao, Linlin; Chen, Zheng; Soutto, Mohammed; Zhu, Shoumin; Lu, Heng; Romero-Gallo, Judith; Peek, Richard; Zhang, Shutian; El-Rifai, Wael

Methylation of the HOXA10 Promoter Directs miR-196b-5p-Dependent Cell Proliferation and Invasion of Gastric Cancer Cells

HOXA10启动子甲基化指导miR-196b-5p依赖的胃癌细胞增殖和侵袭

期刊:Molecular Cancer Research

影响因子:4.7

doi:10.1158/1541-7786.MCR-17-0655

Shao, Linlin; Chen, Zheng; Peng, Dunfa; Soutto, Mohammed; Zhu, Shoumin; Bates, Andreia; Zhang, Shutian; El-Rifai, Wael

Targeting APE1-Redox Function Reverses SOX9-mediated Chemoresistance in Esophageal Adenocarcinoma

靶向 APE1 氧化还原功能可逆转 SOX9 介导的食管腺癌化疗耐药性

Enhancing the antitumor efficacy using a combination of FGFR4 Inhibitor (H3B-6527) and oxaliplatin in gastric cancer.

在胃癌治疗中，FGFR4抑制剂（H3B-6527）与奥沙利铂联合应用可增强抗肿瘤疗效。

CDK1 drives SOX9-mediated chemotherapeutic resistance in gastric cancer.

CDK1 驱动 SOX9 介导的胃癌化疗耐药性。

SOX9 is regulated by AURKA in response to Helicobacter pylori infection via EIF4E-mediated cap-dependent translation

SOX9 受 AURKA 调控，响应幽门螺杆菌感染，其调控机制是通过 EIF4E 介导的帽依赖性翻译。

Multivalent tyrosine kinase inhibition promotes T cell recruitment to immune-desert gastric cancers by restricting epithelial-mesenchymal transition via tumour-intrinsic IFN-γ signalling

多价酪氨酸激酶抑制剂通过限制肿瘤内在的IFN-γ信号通路介导的上皮-间质转化，促进T细胞募集至免疫沙漠胃癌部位。

Reflux conditions induce E-cadherin cleavage and EMT via APE1 redox function in oesophageal adenocarcinoma

反流条件通过APE1氧化还原功能诱导食管腺癌中E-钙黏蛋白裂解和上皮间质转化（EMT）。

Helicobacter pylori-induced RASAL2 Through Activation of Nuclear Factor-κB Promotes Gastric Tumorigenesis via β-catenin Signaling Axis

幽门螺杆菌诱导的RASAL2通过激活核因子-κB，经由β-catenin信号通路促进胃肿瘤发生

Integrated Analysis of Mouse and Human Gastric Neoplasms Identifies Conserved microRNA Networks in Gastric Carcinogenesis

对小鼠和人类胃肿瘤的综合分析揭示了胃癌发生过程中保守的microRNA网络

Helicobacter pylori-induced miR-135b-5p promotes cisplatin resistance in gastric cancer

幽门螺杆菌诱导的miR-135b-5p促进胃癌对顺铂的耐药性

Methylation of the HOXA10 Promoter Directs miR-196b-5p-Dependent Cell Proliferation and Invasion of Gastric Cancer Cells

HOXA10启动子甲基化指导miR-196b-5p依赖的胃癌细胞增殖和侵袭