Spaargaren Marcel相关文献与解析，生知库

Mobach Simon, Bergkamp Nick D, Ma Ziliang, Haselager Marco V, Anbuhl Stephanie M, Jurriens Daphne, van den Bor Jelle, Wang Ziming, Crudden Caitrin, Roos Jamie L, Perez Almeria Claudia V, Boergonje Rick A, Lohse Martin J, Bosma Reggie, Eldering Eric, Siderius Marco, Wu Wei, Spaargaren Marcel, Tonino Sanne H, Kater Arnon P, Smit Martine J, Heukers Raimond

肿瘤

肿瘤免疫

发表日期：2025

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Targeting Wnt/β-catenin signaling enhances the efficacy of anti-CD38 immunotherapy in multiple myeloma

靶向Wnt/β-catenin信号通路可增强抗CD38免疫疗法在多发性骨髓瘤中的疗效

期刊:Neoplasia

影响因子:7.7

doi:10.1016/j.neo.2025.101242

Li, Heng; Chen, Yunguang; Gregorova, Michaela; Yang, Tingting; Zhang, Xiayi; Yu, Xiaoyu; Wang, Zhen; Hua, Haiying; Ye, Long; Qi, Xiaowei; Spaargaren, Marcel; Pals, Steven T; Ren, Zemin

Presentation of CXCL12Î³ by heparan sulfate proteoglycans activates CXCR4 without desensitization in normal and malignant B cells.

硫酸乙酰肝素蛋白聚糖呈递 CXCL12α 可激活正常和恶性 B 细胞中的 CXCR4，而不会发生脱敏

期刊:Blood Advances

影响因子:7.1

doi:10.1182/bloodadvances.2024014396

Lantermans Hildo C, Ma Fangxue, Kuil Annemieke, de Rooij Martin F M, Bergkamp Nick D, van der Meer Werner, van Buul Jaap D, Smit Martine J, Kersten Marie JosÃ©, Spaargaren Marcel, Pals Steven T

AKT supports the metabolic fitness of multiple myeloma cells by restricting FOXO activity

AKT通过限制FOXO活性来维持多发性骨髓瘤细胞的代谢适应性。

期刊:Blood Advances

影响因子:7.1

doi:10.1182/bloodadvances.2022007383

Bloedjes, Timon A; de Wilde, Guus; Khan, Gerarda H; Ashby, Timothy C; Shaughnessy, John D; Zhan, Fenghuang; Houtkooper, Riekelt H; Bende, Richard J; van Noesel, Carel J M; Spaargaren, Marcel; Guikema, Jeroen E J

Tipping the balance: toward rational combination therapies to overcome venetoclax resistance in mantle cell lymphoma

扭转乾坤：迈向合理的联合疗法以克服套细胞淋巴瘤对维奈托克的耐药性

期刊:Leukemia

影响因子:13.4

doi:10.1038/s41375-022-01627-9

Thus, Yvonne J; Eldering, Eric; Kater, Arnon P; Spaargaren, Marcel

Redirecting T-cell Activity with Anti-BCMA/Anti-CD3 Bispecific Antibodies in Chronic Lymphocytic Leukemia and Other B-cell Lymphomas

利用抗BCMA/抗CD3双特异性抗体重新定向T细胞活性治疗慢性淋巴细胞白血病和其他B细胞淋巴瘤

期刊:Cancer Research Communications

影响因子:3.3

doi:10.1158/2767-9764.CRC-22-0083

Martens, Anne W J; Rietveld, Joanne M; de Boer, Renate; Peters, Fleur S; Ngo, An; van Mil, Lotte W H G; de Heer, Koen; Spaargaren, Marcel; Verkleij, Christie P M; van de Donk, Niels W C J; Adams, Homer C 3rd; Eldering, Eric; van Noesel, Carel J M; Verona, Raluca; Kater, Arnon P

The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma

CXCL12γ趋化因子被硫酸乙酰肝素固定在基质细胞上，从而控制细胞黏附并介导多发性骨髓瘤的耐药性。

期刊:Journal of Hematology & Oncology

影响因子:40.4

doi:10.1186/s13045-021-01031-3

Ren, Zemin; Lantermans, Hildo; Kuil, Annemieke; Kraan, Willem; Arenzana-Seisdedos, Fernando; Kersten, Marie José; Spaargaren, Marcel; Pals, Steven T

Correction to: The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma

更正：CXCL12γ趋化因子被硫酸乙酰肝素固定在基质细胞上，从而控制细胞黏附并介导多发性骨髓瘤的耐药性。

期刊:Journal of Hematology & Oncology

影响因子:40.4

doi:10.1186/s13045-021-01038-w

Ren, Zemin; Lantermans, Hildo; Kuil, Annemieke; Kraan, Willem; Arenzana-Seisdedos, Fernando; Kersten, Marie José; Spaargaren, Marcel; Pals, Steven T

Immune evasion in primary testicular and central nervous system lymphomas: HLA loss rather than 9p24.1/PD-L1/PD-L2 alterations

原发性睾丸和中枢神经系统淋巴瘤的免疫逃逸：HLA 缺失而非 9p24.1/PD-L1/PD-L2 改变

期刊:Blood

影响因子:23.1

doi:10.1182/blood.2021011366

Minderman, Marthe; Amir, Avital; Kraan, Willem; Schilder-Tol, Esther J M; Oud, Monique E C M; Scheepstra, Cornelis G; Noorduyn, Arnold L; Kluin, Philip M; Kersten, Marie José; Spaargaren, Marcel; Pals, Steven T

MYD88 mutations identify a molecular subgroup of diffuse large B-cell lymphoma with an unfavorable prognosis

MYD88 突变可识别出弥漫性大 B 细胞淋巴瘤的一个分子亚型，该亚型预后不良。

期刊:Haematologica

影响因子:7.9

doi:10.3324/haematol.2018.214122

Vermaat, Joost S; Somers, Sebastiaan F; de Wreede, Liesbeth C; Kraan, Willem; de Groen, Ruben A L; Schrader, Anne M R; Kerver, Emile D; Scheepstra, Cornelis G; Berenschot, Henriëtte; Deenik, Wendy; Wegman, Jurgen; Broers, Rianne; de Boer, Jan-Paul D; Nijland, Marcel; van Wezel, Tom; Veelken, Hendrik; Spaargaren, Marcel; Cleven, Arjen H; Kersten, Marie José; Pals, Steven T

Disruption of constitutive CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms.

CXCR4 寡聚体的组成破坏会损害淋巴瘤的致癌特性

Targeting Wnt/β-catenin signaling enhances the efficacy of anti-CD38 immunotherapy in multiple myeloma

靶向Wnt/β-catenin信号通路可增强抗CD38免疫疗法在多发性骨髓瘤中的疗效

Presentation of CXCL12Î³ by heparan sulfate proteoglycans activates CXCR4 without desensitization in normal and malignant B cells.

硫酸乙酰肝素蛋白聚糖呈递 CXCL12α 可激活正常和恶性 B 细胞中的 CXCR4，而不会发生脱敏

AKT supports the metabolic fitness of multiple myeloma cells by restricting FOXO activity

AKT通过限制FOXO活性来维持多发性骨髓瘤细胞的代谢适应性。

Tipping the balance: toward rational combination therapies to overcome venetoclax resistance in mantle cell lymphoma

扭转乾坤：迈向合理的联合疗法以克服套细胞淋巴瘤对维奈托克的耐药性

Redirecting T-cell Activity with Anti-BCMA/Anti-CD3 Bispecific Antibodies in Chronic Lymphocytic Leukemia and Other B-cell Lymphomas

利用抗BCMA/抗CD3双特异性抗体重新定向T细胞活性治疗慢性淋巴细胞白血病和其他B细胞淋巴瘤

The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma

CXCL12γ趋化因子被硫酸乙酰肝素固定在基质细胞上，从而控制细胞黏附并介导多发性骨髓瘤的耐药性。

Correction to: The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma

更正：CXCL12γ趋化因子被硫酸乙酰肝素固定在基质细胞上，从而控制细胞黏附并介导多发性骨髓瘤的耐药性。

Immune evasion in primary testicular and central nervous system lymphomas: HLA loss rather than 9p24.1/PD-L1/PD-L2 alterations

原发性睾丸和中枢神经系统淋巴瘤的免疫逃逸：HLA 缺失而非 9p24.1/PD-L1/PD-L2 改变

MYD88 mutations identify a molecular subgroup of diffuse large B-cell lymphoma with an unfavorable prognosis

MYD88 突变可识别出弥漫性大 B 细胞淋巴瘤的一个分子亚型，该亚型预后不良。