KRASG12R-Mutant Pancreatic Cancer Features Limited ERK/MAPK Transcriptional Activity and a Distinctive Tumor Microenvironment
KRASG12R突变型胰腺癌具有ERK/MAPK转录活性受限和独特的肿瘤微环境。
期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-25-2630
Burge, Rachel A; Le Roux, Ozgun; Popow, Olesja; Spadafora, Victoria K; Rajesh, Christabelle; Adair, Sara J; Bialousow, Lucas; Murphy, Cailey; Saberi, Samaneh; Vaena, Silvia G; Taquey, Margaret C; Allen, Sarah; Han, Lu; Helke, Kristi L; Sharma, Sudarshana; Ostrowski, Michael C; Guttridge, Denis C; Dincman, Toros A; Bauer, Todd W; Kashatus, David F; McFall, Thomas; Haigis, Kevin M; Hollingsworth, Michael A; Counter, Christopher M; Der, Channing J; Hobbs, G Aaron
肿瘤
肿瘤免疫
MAPK/ERK
胰腺癌
RAS
肿瘤微环境
