日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Balancing the extremes for antibody developability: hydrophobic and electrostatic germline framework signatures for CDR-loop compensation

平衡抗体开发中的极端因素:用于补偿 CDR 环的疏水性和静电种系框架特征

Spanke, Vera A; Egger-Hoerschinger, Valentin J; Seidler, Clarissa A; Kroell, Katharina B; Wieser, Vincent; Imhof-Jung, Sabine; Weiche, Benjamin; Bujotzek, Alexander; Georges, Guy; Liedl, Klaus R

Polymerization from Lipid Membranes

脂质膜的聚合

Torzynski, Alexandre L; Grimm, Dominique; Romio, Matteo; François-Martin, Claire; Spanke, Hendrik; Wolfisberg, Gianna; Staykova, Margarita; Benetti, Edmondo M; Dufresne, Eric R

Data-driven analyses of human antibody variable domain germlines: pairings, sequences and structural features

基于数据的人类抗体可变区种系分析:配对、序列和结构特征

Seidler, Clarissa A; Spanke, Vera A; Gamper, Jakob; Bujotzek, Alexander; Georges, Guy; Liedl, Klaus R

Glutaminolysis impairment and immunometabolic dysregulation in U937 cells: Key mechanisms in occupational and environmental skin exposure to UV and benzo[a]pyrene

U937细胞中谷氨酰胺分解代谢受损和免疫代谢紊乱:职业和环境皮肤暴露于紫外线和苯并[a]芘的关键机制

Kersch, Christian; Masutin, Viktor; Kuhlmann, Laura; Alsaleh, Rasha; Kaifie, Andrea; Schmitz-Spanke, Simone

Benzo[a]pyrene and UV light co-exposure: differential effects on oxidative stress and genotoxicity in human keratinocytes and ex vivo skin

苯并[a]芘与紫外线共同暴露:对人角质形成细胞和离体皮肤氧化应激和遗传毒性的不同影响

Kersch, Christian; Masutin, Viktor; Alsaleh, Rasha; Schmitz-Spanke, Simone

Solvent-Site Prediction for Fragment Docking and Its Implication on Fragment-Based Drug Discovery

溶剂位点预测在片段对接中的应用及其对基于片段的药物发现的意义

Almena Rodriguez, Laura; Spanke, Vera A; Kersten, Christian

Exploring the Activation of the Keap1-Nrf2-ARE Pathway by PAHs in Children's Toys

探究儿童玩具中多环芳烃对 Keap1-Nrf2-ARE 通路的激活作用

Lauenstein, Jonas; van de Weyer, Simon; Alsaleh, Rasha; Wiedmer, Christoph; Buettner, Andrea; Kersch, Christian; Schmitz-Spanke, Simone

Tolterodine is a novel candidate for assessing CYP3A4 activity through metabolic volatiles to predict drug responses

托特罗定是一种新型候选药物,可通过代谢挥发物评估CYP3A4活性,从而预测药物反应。

Stock, Valentina; Hofer, Rebecca; Lochmann, Franziska; Spanke, Vera; Liedl, Klaus R; Troppmair, Jakob; Langer, Thierry; Gstach, Hubert; Dank, Christian; Mayhew, Chris A; Kammerer, Sarah; Ruzsanyi, Veronika

From closed to open: three dynamic states of membrane-bound cytochrome P450 3A4

从关闭到开放:膜结合细胞色素P450 3A4的三种动态状态

Spanke, Vera A; Egger-Hoerschinger, Valentin J; Ruzsanyi, Veronika; Liedl, Klaus R

Usability and accuracy of two different aortic annulus sizing software programs in patients undergoing transcatheter aortic valve replacement

两种不同的主动脉瓣环尺寸测量软件在经导管主动脉瓣置换术患者中的可用性和准确性

Spanke, Johannes; Nübel, Jonathan; Hölschermann, Frank; Tambor, Grit; Kiessling, Claudia; Kaneko, Hidehiro; Haase-Fielitz, Anja; Butter, Christian