The peroxisome proliferator-activated receptor agonist pioglitazone and 5-lipoxygenase inhibitor zileuton have no effect on lung inflammation in healthy volunteers by positron emission tomography in a single-blind placebo-controlled cohort study
在一项单盲安慰剂对照队列研究中,过氧化物酶体增殖物激活受体激动剂吡格列酮和5-脂氧合酶抑制剂齐留通对健康志愿者的肺部炎症没有影响(通过正电子发射断层扫描评估)。
期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0191783
Chen, Delphine L; Huang, Howard J; Byers, Derek E; Shifren, Adrian; Belikoff, Bryan; Engle, Jacquelyn T; Arentson, Elizabeth; Kemp, Debra; Phillips, Sharon; Scherrer, David E; Fujiwara, Hideji; Spayd, Katherine J; Brooks, Frank J; Pierce, Richard A; Castro, Mario; Isakow, Warren