日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanistic insights into G-protein coupling with an agonist-bound G-protein-coupled receptor.

对激动剂结合的 G 蛋白偶联受体的 G 蛋白偶联机制的深入了解

Batebi Hossein, Pérez-Hernández Guillermo, Rahman Sabrina N, Lan Baoliang, Kamprad Antje, Shi Mingyu, Speck David, Tiemann Johanna K S, Guixà-González Ramon, Reinhardt Franziska, Stadler Peter F, Papasergi-Scott Makaía M, Skiniotis Georgios, Scheerer Patrick, Kobilka Brian K, Mathiesen Jesper M, Liu Xiangyu, Hildebrand Peter W

Angiotensin and Endothelin Receptor Structures With Implications for Signaling Regulation and Pharmacological Targeting

血管紧张素和内皮素受体结构及其对信号调控和药物靶向治疗的影响

Speck, David; Kleinau, Gunnar; Szczepek, Michal; Kwiatkowski, Dennis; Catar, Rusan; Philippe, Aurélie; Scheerer, Patrick

Signal Transduction and Pathogenic Modifications at the Melanocortin-4 Receptor: A Structural Perspective

黑皮质素-4受体的信号转导和致病修饰:结构视角

Heyder, Nicolas; Kleinau, Gunnar; Szczepek, Michal; Kwiatkowski, Dennis; Speck, David; Soletto, Lucia; Cerdá-Reverter, José Miguel; Krude, Heiko; Kühnen, Peter; Biebermann, Heike; Scheerer, Patrick

Activation of NF-κB via endosomal Toll-like receptor 7 (TLR7) or TLR9 suppresses murine herpesvirus 68 reactivation

通过内体 Toll 样受体 7 (TLR7) 或 TLR9 激活 NF-κB 可抑制鼠疱疹病毒 68 的再激活

Florian Haas, Kazuma Yamauchi, Monika Murat, Michele Bernasconi, Noboru Yamanaka, Roberto F Speck, David Nadal

Early gene expression changes by Epstein-Barr virus infection of B-cells indicate CDKs and survivin as therapeutic targets for post-transplant lymphoproliferative diseases

EB 病毒感染 B 细胞引起的早期基因表达变化表明 CDK 和 survivin 是移植后淋巴增生性疾病的治疗靶点

Michele Bernasconi, Seigo Ueda, Patricia Krukowski, Beat C Bornhauser, Kristin Ladell, Marcus Dorner, Juerg A Sigrist, Cristina Campidelli, Roberta Aslandogmus, Davide Alessi, Christoph Berger, Stefano A Pileri, Roberto F Speck, David Nadal

beta1 integrin expression increases susceptibility of memory B cells to Epstein-Barr virus infection

β1整合素表达增加记忆B细胞对EB病毒感染的易感性

Marcus Dorner ,Franziska Zucol, Davide Alessi, Stephan K Haerle, Walter Bossart, Markus Weber, Rahel Byland, Michele Bernasconi, Christoph Berger, Sharof Tugizov, Roberto F Speck, David Nadal