Spender相关文献与解析，生知库 | 链接生命科学的每一步

Liang, Akun; Ten Eikelder, Henricus R A; Ranieri, Umbertoluca; Spender, James; Massani, Bernhard; Fedotenko, Timofey; Glazyrin, Konstantin; Giordano, Nico; Lawrence Bright, Eleanor; Wright, Jonathan; Shi, Lan-Ting; Trybel, Florian; Laniel, Dominique

发表日期：2026

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AKT/mTOR as a targetable hub to overcome multimodal resistance to EGFR inhibitors in oesophageal squamous cell carcinoma

AKT/mTOR作为可靶向的枢纽，有望克服食管鳞状细胞癌对EGFR抑制剂的多模式耐药性

期刊:British Journal of Cancer

影响因子:6.8

doi:10.1038/s41416-025-03093-3

Spender, Lindsay C; Watt, Dale M; Baxter, Mark A; Shuttleworth, Morven K; Walker, Kateah; Savage, Alice R; Clements, Hollie A; Kapelyukh, Yury; Bray, Susan E; King, Sharon I; Wolf, C Roland; Inman, Gareth J; Walsh, Shaun V; Blyth, Karen; Petty, Russell D

Synthesis of LaCN(3), TbCN(3), CeCN(5), and TbCN(5) Polycarbonitrides at Megabar Pressures

在兆巴压力下合成 LaCN(3)、TbCN(3)、CeCN(5) 和 TbCN(5) 多碳氮化物

期刊:Journal of the American Chemical Society

影响因子:15.6

doi:10.1021/jacs.4c06068

Aslandukov, Andrey; Liang, Akun; Ehn, Amanda; Trybel, Florian; Yin, Yuqing; Aslandukova, Alena; Akbar, Fariia I; Ranieri, Umbertoluca; Spender, James; Howie, Ross T; Bright, Eleanor Lawrence; Wright, Jonathan; Hanfland, Michael; Garbarino, Gaston; Mezouar, Mohamed; Fedotenko, Timofey; Abrikosov, Igor A; Dubrovinskaia, Natalia; Dubrovinsky, Leonid; Laniel, Dominique

发表日期：2024

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An investigation of the clinical impact and therapeutic relevance of a DNA damage immune response (DDIR) signature in patients with advanced gastroesophageal adenocarcinoma

一项关于DNA损伤免疫反应（DDIR）特征在晚期胃食管腺癌患者中的临床影响和治疗相关性的研究

期刊:ESMO Open

影响因子:8.3

doi:10.1016/j.esmoop.2024.103450

Baxter, M A; Spender, L C; Cairns, D; Walsh, S; Oparka, R; Porter, R J; Bray, S; Skinner, G; King, S; Turbitt, J; Collinson, D; Miedzybrodzka, Z H; Jellema, G; Logan, G; Kennedy, R D; Turkington, R C; McLean, M H; Swinson, D; Grabsch, H I; Lord, S; Seymour, M J; Hall, P S; Petty, R D

C1orf106 (INAVA) Is a SMAD3-Dependent TGF-β Target Gene That Promotes Clonogenicity and Correlates with Poor Prognosis in Breast Cancer

C1orf106 (INAVA) 是一种 SMAD3 依赖性 TGF-β 靶基因，可促进克隆形成并与乳腺癌预后不良相关

期刊:Cells

影响因子:5.1

doi:10.3390/cells13181530

Lauren S Strathearn, Lindsay C Spender, Christina Schoenherr, Susan Mason, Ruaridh Edwards, Karen Blyth, Gareth J Inman

Title: Structure determination of ζ-N2 from single-crystal X-ray diffraction and theoretical suggestion for the formation of amorphous nitrogen

标题：通过单晶 X 射线衍射确定 ζ-N2 的结构以及对非晶态氮形成的理论建议

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-023-41968-2

Dominique Laniel, Florian Trybel, Andrey Aslandukov, James Spender, Umbertoluca Ranieri, Timofey Fedotenko, Konstantin Glazyrin, Eleanor Lawrence Bright, Stella Chariton, Vitali B Prakapenka, Igor A Abrikosov, Leonid Dubrovinsky, Natalia Dubrovinskaia

发表日期：2023

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The friendships of children and youth with attention-deficit hyperactivity disorder: A systematic review

注意力缺陷多动障碍儿童和青少年的友谊：一项系统性综述

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0289539

Spender, Katherine; Chen, Yu-Wei Ryan; Wilkes-Gillan, Sarah; Parsons, Lauren; Cantrill, Alycia; Simon, Megan; Garcia, Abbygale; Cordier, Reinie

发表日期：2023

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Melanoma secretion of transforming growth factor-β2 leads to loss of epidermal AMBRA1 threatening epidermal integrity and facilitating tumour ulceration

黑色素瘤分泌转化生长因子-β2导致表皮AMBRA1丧失，威胁表皮完整性并促进肿瘤溃疡

期刊:British Journal of Dermatology

影响因子:11

doi:10.1111/bjd.20889

I Cosgarea, A T McConnell, T Ewen, D Tang, D S Hill, M Anagnostou, M Elias, R A Ellis, A Murray, L C Spender, P Giglio, M Gagliardi, A Greenwood, M Piacentini, G J Inman, G M Fimia, M Corazzari, J L Armstrong, P E Lovat

Interactions between anti-EGFR therapies and cytotoxic chemotherapy in oesophageal squamous cell carcinoma: why clinical trials might have failed and how they could succeed

抗EGFR疗法与细胞毒性化疗在食管鳞状细胞癌中的相互作用：临床试验失败的原因及成功之道

期刊:Cancer Chemotherapy and Pharmacology

影响因子:2.3

doi:10.1007/s00280-020-04187-w

Meemanage, Madusha; Spender, Lindsay C; Collinson, Diane; Iannetta, Joanna; Challapalli, Pranavi; Turbitt, Julie; Clark, Caroline; Baxter, Mark; Murray, Graeme; Walsh, Shaun; Miedzybrodzka, Zofia; Petty, Russell D

Preclinical Evaluation of AZ12601011 and AZ12799734, Inhibitors of Transforming Growth Factor β Superfamily Type 1 Receptors

转化生长因子 β 超家族 1 型受体抑制剂 AZ12601011 和 AZ12799734 的临床前评估

期刊:Molecular Pharmacology

影响因子:3.2

doi:10.1124/mol.118.112946

Lindsay C Spender, G John Ferguson, Gareth D Hughes, Barry R Davies, Frederick W Goldberg, Blanca Herrera, Richard G Taylor, Lauren S Strathearn, Owen J Sansom, Simon T Barry, Gareth J Inman

信号转导

发表日期：2019

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High-Pressure Synthesis of the First Thermodynamically Stable Silver Nitride, AgN(5)

高压合成首个热力学稳定的氮化银 AgN(5)

AKT/mTOR as a targetable hub to overcome multimodal resistance to EGFR inhibitors in oesophageal squamous cell carcinoma

AKT/mTOR作为可靶向的枢纽，有望克服食管鳞状细胞癌对EGFR抑制剂的多模式耐药性

Synthesis of LaCN(3), TbCN(3), CeCN(5), and TbCN(5) Polycarbonitrides at Megabar Pressures

在兆巴压力下合成 LaCN(3)、TbCN(3)、CeCN(5) 和 TbCN(5) 多碳氮化物

An investigation of the clinical impact and therapeutic relevance of a DNA damage immune response (DDIR) signature in patients with advanced gastroesophageal adenocarcinoma

一项关于DNA损伤免疫反应（DDIR）特征在晚期胃食管腺癌患者中的临床影响和治疗相关性的研究

C1orf106 (INAVA) Is a SMAD3-Dependent TGF-β Target Gene That Promotes Clonogenicity and Correlates with Poor Prognosis in Breast Cancer

C1orf106 (INAVA) 是一种 SMAD3 依赖性 TGF-β 靶基因，可促进克隆形成并与乳腺癌预后不良相关

Title: Structure determination of ζ-N2 from single-crystal X-ray diffraction and theoretical suggestion for the formation of amorphous nitrogen

标题：通过单晶 X 射线衍射确定 ζ-N2 的结构以及对非晶态氮形成的理论建议

The friendships of children and youth with attention-deficit hyperactivity disorder: A systematic review

注意力缺陷多动障碍儿童和青少年的友谊：一项系统性综述

Melanoma secretion of transforming growth factor-β2 leads to loss of epidermal AMBRA1 threatening epidermal integrity and facilitating tumour ulceration

黑色素瘤分泌转化生长因子-β2导致表皮AMBRA1丧失，威胁表皮完整性并促进肿瘤溃疡

Interactions between anti-EGFR therapies and cytotoxic chemotherapy in oesophageal squamous cell carcinoma: why clinical trials might have failed and how they could succeed

抗EGFR疗法与细胞毒性化疗在食管鳞状细胞癌中的相互作用：临床试验失败的原因及成功之道

Preclinical Evaluation of AZ12601011 and AZ12799734, Inhibitors of Transforming Growth Factor β Superfamily Type 1 Receptors

转化生长因子 β 超家族 1 型受体抑制剂 AZ12601011 和 AZ12799734 的临床前评估