日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Independent Testing of Published CT Models for PD-L1 Status in Non-Small Cell Lung Cancer

对已发表的用于检测非小细胞肺癌中PD-L1状态的CT模型进行独立测试

O'Shea, Robert; Horst, Carolyn; Manickavasagar, Thubeena; Josephides, Eleni; Hunter, Sarah; Taniere, Phillipe; Nonaka, Daisuke; Van Hemelrijck, Mieke; Spicer, James; Hughes, Daniel J; Cook, Gary J R; Bille, Andrea; Karapanagiotou, Eleni; Goh, Vicky

AllergoOncology in Review: Harnessing Allergy in the Field of Oncology to Improve Patient Outcomes

过敏肿瘤学综述:利用过敏学改善肿瘤患者预后

Zydron, Jakub; Balaji, Anishaa; Chauhan, Jitesh; Alder, Jack; Chen, Xinyi; Wiegman, Anna M F; Poli, Aurelie; Jacków-Malinowska, Joanna; Cheeseman, Jack; Spencer, Daniel I R; McDonnell, James; Spicer, James; McCraw, Alexandra J; Karagiannis, Sophia N

AllergoOncology: Emerging Translational and Clinical Significance of Basophils and Mast Cells in Cancer

过敏肿瘤学:嗜碱性粒细胞和肥大细胞在癌症治疗中日益凸显的转化和临床意义

Alder, Jack; Lacy, Katie E; Josephs, Debra H; Spicer, James; Bax, Heather J; Karagiannis, Sophia N; Chauhan, Jitesh

Hyperinflammatory repolarisation of ovarian cancer patient macrophages by anti-tumour IgE antibody, MOv18, restricts an immunosuppressive macrophage:Treg cell interaction

抗肿瘤IgE抗体MOv18诱导卵巢癌患者巨噬细胞发生过度炎症性极化,从而限制了免疫抑制性巨噬细胞与Treg细胞的相互作用。

Osborn, Gabriel; López-Abente, Jacobo; Adams, Rebecca; Laddach, Roman; Grandits, Melanie; Bax, Heather J; Chauhan, Jitesh; Pellizzari, Giulia; Nakamura, Mano; Stavraka, Chara; Chenoweth, Alicia; Palhares, Lais C G F; Evan, Theodore; Lim, Jessica Hui Cheah; Gross, Amanda; Moise, Lenny; Jatiani, Shashi; Figini, Mariangela; Bianchini, Rodolfo; Jensen-Jarolim, Erika; Ghosh, Sharmistha; Montes, Ana; Sayasneh, Ahmad; Kristeleit, Rebecca; Tsoka, Sophia; Spicer, James; Josephs, Debra H; Karagiannis, Sophia N

An oral heme oxygenase inhibitor targets immunosuppressive perivascular macrophages in preclinical models of cancer.

口服血红素加氧酶抑制剂靶向癌症临床前模型中的免疫抑制性血管周围巨噬细胞

Bahri Meriem, Al-Adhami Taha, Demirel Emre, Sarkar Jit, Feehan Karen T, Anstee Joanne E, Cheung Tik Shing, Sosnowska Dominika, Woodman Chloé A, Macmorland William, Yang Dorothy D, Rosekilly James, Gitsaki-Taylor Renee, Gillett Cheryl E, Scudamore Cheryl L, Spicer James, Rahman Khondaker Miraz, Arnold James N

Non-Allergic Urticarial Skin Reactions Associated With MOv18 IgE, a First-In-Class IgE Antibody Recognising Folate Receptor Alpha

与 MOv18 IgE 相关的非过敏性荨麻疹样皮肤反应,MOv18 IgE 是一种首创的识别叶酸受体 α 的 IgE 抗体

Stavraka, Chara; Chauhan, Jitesh; Crescioli, Silvia; McSweeney, Sheila M; Pope, Amy; Gillett, Cheryl; Di Meo, Ashley; Prassas, Ioannis; Laddach, Roman; Stoker, Katie; McCraw, Alexandra J; Adams, Rebecca; Tull, Thomas J; Naban, Nabeel; Willsmore, Zena; Semkova, Kristina V; Grattan, Clive E H; McGrath, John; Till, Stephen J; Corrigan, Christopher J; Kristeleit, Rebecca; Tsoka, Sophia; Diamandis, Eleftherios P; Lacy, Katie E; Pinder, Sarah; Josephs, Debra H; Spicer, James; Bax, Heather J; Karagiannis, Sophia N

Assessment of biophysical properties of the first-in-class anti-cancer IgE antibody drug MOv18 IgE demonstrates monomeric purity and stability

对首创抗癌IgE抗体药物MOv18 IgE的生物物理特性评估表明其具有单体纯度和稳定性。

Considine, Paul; Punnabhum, Panida; Davidson, Callum G; Armstrong, Georgina B; Kreiner, Michaela; Bax, Heather J; Chauhan, Jitesh; Spicer, James; Josephs, Debra H; Karagiannis, Sophia N; Halbert, Gavin; Rattray, Zahra

Physiochemical and functional evaluation of the first-in-class anti-cancer IgE antibody drug, MOv18, through process development and good manufacturing practice production.

通过工艺开发和良好生产规范生产,对首创抗癌 IgE 抗体药物 MOv18 进行理化和功能评价。

Bax Heather J, Chauhan Jitesh, McCraw Alexandra J, Grandits Melanie, Stavraka Chara, Lentfer Heike, Hillyer Tim, Carroll Simon, Vigor Kim, Selkirk Chris, Figini Mariangela, Cheeseman Jack, Urbanowicz Paulina A, Gardner Richard A, Spencer Daniel I R, Westwood Nigel, Mellor Sarah, Spicer James, Josephs Debra H, Karagiannis Sophia N

Long term efficacy of first-line afatinib and the clinical utility of ctDNA monitoring in patients with suspected or confirmed EGFR mutant non-small cell lung cancer who were unsuitable for chemotherapy

一线阿法替尼治疗的长期疗效以及ctDNA监测在疑似或确诊EGFR突变型非小细胞肺癌且不适合化疗的患者中的临床应用价值

Popat, Sanjay; Januszewski, Adam; O'Brien, Mary; Ahmad, Tanya; Lewanski, Conrad; Dernedde, Ulrike; Jankowska, Petra; Mulatero, Clive; Shah, Riyaz; Hicks, Jonathan; Geldart, Tom; Cominos, Mathilda; Gray, Gill; Spicer, James; Bell, Karen; Roitt, Simon; Morris, Clive; Ngai, Yenting; Hughes, Laura; Hackshaw, Allan; Wilson, William

PD-L1 imaging with [(99m)Tc]NM-01 SPECT/CT is associated with metabolic response to pembrolizumab with/without chemotherapy in advanced lung cancer

PD-L1 显像(采用 [(99m)Tc]NM-01 SPECT/CT)与晚期肺癌患者接受帕博利珠单抗联合或不联合化疗后的代谢反应相关

Hughes, Daniel Johnathan; Chand, Gitasha; Johnson, Jessica; Tegala, Ronan; Bailey, Damion; Adamson, Kathryn; Edmonds, Scott; Meszaros, Levente K; Moore, Amelia Elizabeth Broomfield; Manickavasagar, Thubeena; Ndagire, Susan; Gennatas, Spyridon; Georgiou, Alexandros; Ghosh, Sharmistha; Josephs, Debra; Karapanagiotou, Eleni; McLean, Emma; Ting, Hong Hoi; Spicer, James; Goh, Vicky; Cook, Gary J R