日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SIPD or psychotic disorder with stimulant use

使用兴奋剂引起的SIPD或精神病性障碍

Lecomte, Tania; Lang, Donna; Potvin, Stéphane; Diotte, Félix; Livet, Audrey; Cimaglia, Melissa; Abdel-Baki, Amal; Villeneuve, Marie; Jutras-Aswad, Didier; Spidel, Alicia

Multi-centre implementation of an Educational program to improve the Cardiac Arrest diagnostic accuracy of ambulance Telecommunicators and survival outcomes for sudden cardiac arrest victims: the EduCATe study design and methodology

一项旨在提高救护车通讯员心脏骤停诊断准确性和改善心脏骤停患者生存率的教育计划的多中心实施:EduCATe 研究的设计和方法

Vaillancourt, Christian; Charette, Manya; Naidoo, Sarika; Taljaard, Monica; Church, Matthew; Hodges, Stephanie; Leduc, Shannon; Christenson, Jim; Cheskes, Sheldon; Dainty, Katie; Feldman, Michael; Goldstein, Judah; Tallon, John; Helmer, Jennie; Sibley, Aaron; Spidel, Matthew; Blanchard, Ian; Garland, Jim; Cyr, Kathryn; Brehaut, Jamie; Dorian, Paul; Lacroix, Colette; Zambon, Sandra; Thiruganasambandamoorthy, Venkatesh

Pre-clinical characterisation of E2814, a high-affinity antibody targeting the microtubule-binding repeat domain of tau for passive immunotherapy in Alzheimer's disease

E2814是一种高亲和力抗体,靶向tau蛋白的微管结合重复结构域,用于阿尔茨海默病被动免疫治疗,本文对其进行了临床前表征。

Malcolm Roberts ,Ioanna Sevastou ,Yoichi Imaizumi ,Kavita Mistry ,Sonia Talma ,Madhurima Dey ,Jane Gartlon ,Hiroshi Ochiai ,Zhi Zhou ,Shigeru Akasofu ,Naoki Tokuhara ,Makoto Ogo ,Muneo Aoyama ,Hirofumi Aoyagi ,Kate Strand ,Ezat Sajedi ,Kishan Lal Agarwala ,Jared Spidel ,Earl Albone ,Kanta Horie ,James M Staddon ,Rohan de Silva

Engineering humanized antibody framework sequences for optimal site-specific conjugation of cytotoxins

构建人源化抗体框架序列以实现细胞毒素的最佳位点特异性结合

Jared L Spidel, Earl F Albone, Xin Cheng, Benjamin Vaessen, Sara Jacob, Andrew Z Milinichik, Arielle Verdi, J Bradford Kline, Luigi Grasso

Generation of therapeutic immunoconjugates via Residue-Specific Conjugation Technology (RESPECT) utilizing a native cysteine in the light chain framework of Oryctolagus cuniculus

利用穴兔轻链框架中的天然半胱氨酸,通过残基特异性结合技术 (RESPECT) 生成治疗性免疫结合物

Earl F Albone, Jared L Spidel, Xin Cheng, Young Chul Park, Sara Jacob, Andrew Z Milinichik, Ben Vaessen, Janet Butler, J Bradford Kline, Luigi Grasso

The antitumor activity of the human FOLR1-specific monoclonal antibody, farletuzumab, in an ovarian cancer mouse model is mediated by antibody-dependent cellular cytotoxicity

人类 FOLR1 特异性单克隆抗体 farletuzumab 在卵巢癌小鼠模型中的抗肿瘤活性是由抗体依赖性细胞毒性介导的

JianMin Lin, Jared L Spidel, Christopher J Maddage, Katherine A Rybinski, Rina P Kennedy, Candice L M Krauthauser, Young Chul Park, Earl F Albone, Sara Jacob, Matthew T Goserud, Bryon P Martinez, Qimin Chao, Yuhong Zhou, Nicholas C Nicolaides, J Bradford Kline, Luigi Grasso

Generation and characterization of high affinity human monoclonal antibodies that neutralize staphylococcal enterotoxin B

中和葡萄球菌肠毒素 B 的高亲和力人单克隆抗体的生成和表征

Brian Drozdowski, Yuhong Zhou, Brad Kline, Jared Spidel, Yin Yin Chan, Earl Albone, Howard Turchin, Qimin Chao, Marianne Henry, Jacqueline Balogach, Eric Routhier, Sina Bavari, Nicholas C Nicolaides, Philip M Sass, Luigi Grasso

Overexpression of carcinoma and embryonic cytotrophoblast cell-specific Mig-7 induces invasion and vessel-like structure formation

癌症和胚胎滋养层细胞特异性 Mig-7 的过度表达诱导侵袭和血管样结构形成

Aaron P Petty, Kiera L Garman, Virginia D Winn, Celee M Spidel, J Suzanne Lindsey