日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Biophysical characterization of blood coagulation factor VIII binding to lipid nanodiscs that mimic activated platelet surfaces

对模拟活化血小板表面的脂质纳米盘与血液凝固因子VIII结合的生物物理学表征

Avery, Nathan G; Young, Isabelle R; Lu, Selena; Vaughan, Jordan D; Korus, Patrick S; Richardson, Tera N; Childers, Kenneth C; Smirnov, Serge L; Spiegel, P Clint Jr

Humanization and functional characterization of enhanced coagulation factor IX variants identified through ancestral sequence reconstruction

通过祖先序列重建鉴定的增强型凝血因子IX变体的人源化和功能表征

Coyle, Christopher W; Knight, Kristopher A; Brown, Harrison C; George, Stephan N; Denning, Gabriela; Branella, Gianna M; Childers, Kenneth C; Spiegel, P Clint; Spencer, H Trent; Doering, Christopher B

Antimicrobial isoflavans and other metabolites of Dalea nana

Dalea nana 的抗菌异黄酮和其他代谢产物

Belofsky, Gil; Cruz, Caroline; Schultz, Trevor; Zapata, Maxwell; Wilcox, Dominique; Wasmund, Brendan; Salomon, Christine E; Spiegel, P Clint

Structure of coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor

凝血因子VIII与患者来源的抗C1结构域抗体抑制剂结合的结构

Childers, Kenneth C; Avery, Nathan G; Estrada Alamo, Kevin A; Davulcu, Omar; Haynes, Rose Marie; Lollar, Pete; Doering, Christopher B; Coxon, Carmen H; Spiegel, P Clint

Stable binding to phosphatidylserine-containing membranes requires conserved arginine residues in tandem C domains of blood coagulation factor VIII.

与含磷脂酰丝氨酸的膜稳定结合需要血液凝固因子 VIII 串联 C 结构域中保守的精氨酸残基

Peters Shaun C, Childers Kenneth C, Mitchell Corbin E, Avery Nathan G, Reese Steven S Jr, Mitchell Cristopher, Wo Serena W, Swanson Christopher D, Brison Caileen M, Spiegel P Clint Jr

Structure of blood coagulation factor VIII in complex with an anti-C1 domain pathogenic antibody inhibitor

血液凝固因子VIII与抗C1结构域致病性抗体抑制剂复合物的结构

Gish, Joseph S; Jarvis, Lexi; Childers, Kenneth C; Peters, Shaun C; Garrels, Connor S; Smith, Ian W; Spencer, H Trent; Doering, Christopher B; Lollar, Pete; Spiegel, P Clint

Structure of Blood Coagulation Factor VIII in Complex With an Anti-C2 Domain Non-Classical, Pathogenic Antibody Inhibitor

血液凝固因子VIII与抗C2结构域非经典致病性抗体抑制剂复合物的结构

Ronayne, Estelle K; Peters, Shaun C; Gish, Joseph S; Wilson, Celena; Spencer, H Trent; Doering, Christopher B; Lollar, Pete; Spiegel, P Clint Jr; Childers, Kenneth C

Rapid Continuous Ruthenium-Catalysed Transfer Hydrogenation of Aromatic Nitriles to Primary Amines

快速连续钌催化芳香腈转移氢化制伯胺

O'Neil, Gregory W; Craig, Alexander M; Williams, John R; Young, Jeffrey C; Spiegel, P Clint; Labes, Ricardo; González-Calderón, Davir; Battilocchio, Claudio; Mateos, Carlos; Cumming, Graham R; de Frutos, Oscar; Rincón, Juan A; Ley, Steven V

The 1.7 Ã X-ray crystal structure of the porcine factor VIII C2 domain and binding analysis to anti-human C2 domain antibodies and phospholipid surfaces.

猪因子 VIII C2 结构域的 1.7 Å X 射线晶体结构及其与抗人 C2 结构域抗体和磷脂表面的结合分析

Brison Caileen M, Mullen Steven M, Wuerth Michelle E, Podolsky Kira, Cook Matthew, Herman Jacob A, Walter Justin D, Meeks Shannon L, Spiegel P Clint

Characterization and solution structure of the factor VIII C2 domain in a ternary complex with classical and non-classical inhibitor antibodies

对VIII因子C2结构域与经典和非经典抑制抗体形成的三元复合物进行表征和溶液结构分析

Walter, Justin D; Werther, Rachel A; Polozova, Maria S; Pohlman, Julie; Healey, John F; Meeks, Shannon L; Lollar, Pete; Spiegel, P Clint Jr