日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Biophysical characterization of blood coagulation factor VIII binding to lipid nanodiscs that mimic activated platelet surfaces

对模拟活化血小板表面的脂质纳米盘与血液凝固因子VIII结合的生物物理学表征

Avery, Nathan G; Young, Isabelle R; Lu, Selena; Vaughan, Jordan D; Korus, Patrick S; Richardson, Tera N; Childers, Kenneth C; Smirnov, Serge L; Spiegel, P Clint Jr

Stable binding to phosphatidylserine-containing membranes requires conserved arginine residues in tandem C domains of blood coagulation factor VIII.

与含磷脂酰丝氨酸的膜稳定结合需要血液凝固因子 VIII 串联 C 结构域中保守的精氨酸残基

Peters Shaun C, Childers Kenneth C, Mitchell Corbin E, Avery Nathan G, Reese Steven S Jr, Mitchell Cristopher, Wo Serena W, Swanson Christopher D, Brison Caileen M, Spiegel P Clint Jr

Structure of Blood Coagulation Factor VIII in Complex With an Anti-C2 Domain Non-Classical, Pathogenic Antibody Inhibitor

血液凝固因子VIII与抗C2结构域非经典致病性抗体抑制剂复合物的结构

Ronayne, Estelle K; Peters, Shaun C; Gish, Joseph S; Wilson, Celena; Spencer, H Trent; Doering, Christopher B; Lollar, Pete; Spiegel, P Clint Jr; Childers, Kenneth C

Characterization and solution structure of the factor VIII C2 domain in a ternary complex with classical and non-classical inhibitor antibodies

对VIII因子C2结构域与经典和非经典抑制抗体形成的三元复合物进行表征和溶液结构分析

Walter, Justin D; Werther, Rachel A; Polozova, Maria S; Pohlman, Julie; Healey, John F; Meeks, Shannon L; Lollar, Pete; Spiegel, P Clint Jr