Development of a cyst-targeted therapy for polycystic kidney disease using an antagonistic dimeric IgA monoclonal antibody against cMET.
利用针对 cMET 的拮抗性二聚体 IgA 单克隆抗体开发针对多囊肾病的囊肿靶向疗法。
期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2025.102335
Schimmel Margaret F, Bourgeois Bryan C, Spindt Alison K, Patel Sage A, Chin Tiffany, Cornick Gavin E, Liu Yuqi, Weimbs Thomas