日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Comparative Analysis of the Transcriptomic Response to Cisplatin in Drug-Sensitive and Drug-Resistant Testicular Germ Cell Tumors

对顺铂敏感型和耐药型睾丸生殖细胞肿瘤转录组反应的比较分析

Khan, Mehwish Wahid; Shokry, Doha; Boyd, Raya I; Singh, Ratnakar; Spinella, Michael J

A Dynamic Shift in Estrogen Receptor Expression During Granulosa Cell Differentiation in the Ovary.

卵巢颗粒细胞分化过程中雌激素受体表达的动态变化

Park Chan Jin, Oh Ji-Eun, Lin PoChing, Zhou Sherry, Bunnell Mary, Bikorimana Emmanuel, Spinella Michael J, Lim Hyunjung Jade, Ko CheMyong J

Comparative hepatotoxicity of novel lithium bis(trifluoromethanesulfonyl)imide (LiTFSI, ie. HQ-115) and legacy Perfluorooctanoic acid (PFOA) in male mice: Insights into epigenetic mechanisms and pathway-specific responses.

新型双(三氟甲磺酰)亚胺锂 (LiTFSI,即 HQ-115) 和传统全氟辛酸 (PFOA) 在雄性小鼠中的肝毒性比较:对表观遗传机制和通路特异性反应的深入了解

Sands Mia, Zhang Xing, Gal Arnon, Laws Mary, Spinella Michael, Erdogan Zeynep-Madak, Irudayaraj Joseph

Refractory testicular germ cell tumors are highly sensitive to the targeting of polycomb pathway demethylases KDM6A and KDM6B

难治性睾丸生殖细胞肿瘤对靶向多梳通路去甲基化酶KDM6A和KDM6B的治疗高度敏感。

Shokry, Doha; Khan, Mehwish W; Powell, Christine; Johnson, Samantha; Rennels, Brayden C; Boyd, Raya I; Sun, Zhengyang; Fazal, Zeeshan; Freemantle, Sarah J; Parker, Maryanna H; Vieson, Miranda D; Samuelson, Jonathan P; Spinella, Michael J; Singh, Ratnakar

Perfluorooctanesulfonic Acid Alters Pro-Cancer Phenotypes and Metabolic and Transcriptional Signatures in Testicular Germ Cell Tumors

全氟辛烷磺酸改变睾丸生殖细胞肿瘤的促癌表型及代谢和转录特征

Boyd, Raya I; Shokry, Doha; Fazal, Zeeshan; Rennels, Brayden C; Freemantle, Sarah J; La Frano, Michael R; Prins, Gail S; Madak Erdogan, Zeynep; Irudayaraj, Joseph; Singh, Ratnakar; Spinella, Michael J

Toward a Mechanistic Understanding of Poly- and Perfluoroalkylated Substances and Cancer

深入理解多氟烷基和全氟烷基物质与癌症的关系

Boyd, Raya I; Ahmad, Saeed; Singh, Ratnakar; Fazal, Zeeshan; Prins, Gail S; Madak Erdogan, Zeynep; Irudayaraj, Joseph; Spinella, Michael J

The Relationship between Typical Environmental Endocrine Disruptors and Kidney Disease

典型环境内分泌干扰物与肾脏疾病的关系

Zhang, Xing; Flaws, Jodi A; Spinella, Michael J; Irudayaraj, Joseph

Between a Rock and a Hard Place: An Epigenetic-Centric View of Testicular Germ Cell Tumors

进退两难:从表观遗传学角度看睾丸生殖细胞肿瘤

Singh, Ratnakar; Fazal, Zeeshan; Freemantle, Sarah J; Spinella, Michael J

Hypermethylation and global remodelling of DNA methylation is associated with acquired cisplatin resistance in testicular germ cell tumours

睾丸生殖细胞肿瘤中DNA甲基化的过度甲基化和整体重塑与获得性顺铂耐药性相关。

Fazal, Zeeshan; Singh, Ratnakar; Fang, Fang; Bikorimana, Emmanuel; Baldwin, Hannah; Corbet, Andrea; Tomlin, Megan; Yerby, Cliff; Adra, Nabil; Albany, Costantine; Lee, Sarah; Freemantle, Sarah J; Nephew, Kenneth P; Christensen, Brock C; Spinella, Michael J

A phase 1 study of combined guadecitabine and cisplatin in platinum refractory germ cell cancer

一项针对铂类耐药生殖细胞癌的 1 期研究,评估了 guadecitabine 联合顺铂的疗效。

Albany, Costantine; Fazal, Zeeshan; Singh, Ratnakar; Bikorimana, Emmanuel; Adra, Nabil; Hanna, Nasser H; Einhorn, Lawrence H; Perkins, Susan M; Sandusky, George E; Christensen, Brock C; Keer, Harold; Fang, Fang; Nephew, Kenneth P; Spinella, Michael J