日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Aberrant splicing in Huntington's disease accompanies disrupted TDP-43 activity and altered m6A RNA modification.

亨廷顿病中的异常剪接伴随着 TDP-43 活性的破坏和 m6A RNA 修饰的改变

Nguyen Thai B, Miramontes Ricardo, Chillon-Marinas Carlos, Maimon Roy, Vazquez-Sanchez Sonia, Lau Alice L, McClure Nicolette R, Wu Zhuoxing, Wang Keona Q, England Whitney E, Singha Monika, Stocksdale Jennifer T, Heath Marie, Jang Ki-Hong, Jung Sunhee, Ling Karen, Jafar-Nejad Paymann, McKnight Jharrayne I, Ho Leanne N, Dalahmah Osama Al, Faull Richard L M, Steffan Joan S, Reidling Jack C, Jang Cholsoon, Lee Gina, Cleveland Don W, Lagier-Tourenne Clotilde, Spitale Robert C, Thompson Leslie M

Novel photocrosslinking chemical probes utilized for high-resolution spatial transcriptomics

用于高分辨率空间转录组学的新型光交联化学探针

Spitalny, Leslie; Falco, Natalie; England, Whitney; Allred, Tyler; Spitale, Robert C

Quantification of subcellular RNA localization through direct detection of RNA oxidation.

通过直接检测 RNA 氧化来量化亚细胞 RNA 定位

Lo Hei-Yong G, Goering Raeann, Kocere Agnese, Lo Joelle, Pockalny Megan C, White Laura K, Ramirez Haydee, Martinez Abraham, Jacobson Seth, Spitale Robert C, Pearson Chad G, Resendiz Marino J E, Mosimann Christian, Taliaferro J Matthew

Probing the dynamic RNA structurome and its functions

探究动态RNA结构组及其功能

Spitale, Robert C; Incarnato, Danny

Exploiting Endogenous Enzymes for Cancer-Cell Selective Metabolic Labeling of RNA in Vivo

利用内源性酶对癌细胞进行体内RNA的选择性代谢标记

Beasley, Samantha; Vandewalle, Abigail; Singha, Monika; Nguyen, Kim; England, Whitney; Tarapore, Eric; Dai, Nan; Corrêa, Ivan R Jr; Atwood, Scott X; Spitale, Robert C

An atlas of posttranslational modifications on RNA binding proteins

RNA结合蛋白翻译后修饰图谱

England, Whitney E; Wang, Jingtian; Chen, Siwei; Baldi, Pierre; Flynn, Ryan A; Spitale, Robert C

An Optimized Enzyme-Nucleobase Pair Enables In Vivo RNA Metabolic Labeling with Improved Cell-Specificity

优化的酶-核碱基对可实现体内RNA代谢标记,并提高细胞特异性

Singha, Monika K; Zimak, Jan; Levine, Samantha R; Dai, Nan; Hong, Chan; Anaraki, Cecily; Gupta, Mrityunjay; Halbrook, Christopher J; Atwood, Scott X; Spitale, Robert C

Repurposing a DNA-Repair Enzyme for Targeted Protein Degradation

将DNA修复酶重新用于靶向蛋白质降解

Fredlender, Callie; Levine, Samantha; Zimak, Jan; Spitale, Robert C

Huntington's disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization

亨廷顿病小鼠和人类脑组织均表现出G3BP1颗粒增多和TDP43错位

Sanchez, Isabella I; Nguyen, Thai B; England, Whitney E; Lim, Ryan G; Vu, Anthony Q; Miramontes, Ricardo; Byrne, Lauren M; Markmiller, Sebastian; Lau, Alice L; Orellana, Iliana; Curtis, Maurice A; Faull, Richard Lewis Maxwell; Yeo, Gene W; Fowler, Christie D; Reidling, Jack C; Wild, Edward J; Spitale, Robert C; Thompson, Leslie M

Chemical Approaches To Analyzing RNA Structure Transcriptome-Wide

利用化学方法分析转录组范围内的RNA结构

England, Whitney E; Garfio, Chely M; Spitale, Robert C