日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cancer in transition: discovery of tumor-intrinsic transcriptional programs shaping the immune and microenvironmental landscape

癌症的转变:发现塑造免疫和微环境景观的肿瘤内在转录程序

Spitschak, Alf; Casalegno Garduño, Rosaely; Pützer, Brigitte M

Integrative Multimodal Profiling of TAp73 and DNp73 Reveals Isoform-Specific Transcriptomic Coregulator Landscapes in Cancer Programs

TAp73 和 DNp73 的整合多模态分析揭示了癌症程序中异构体特异性转录组共调控因子图谱

Möller, Steffen; Spitschak, Alf; Murr, Nico; Pützer, Brigitte M

CD8+ T Cell Subsets as Biomarkers for Predicting Checkpoint Therapy Outcomes in Cancer Immunotherapy

CD8+ T细胞亚群作为预测癌症免疫疗法中检查点疗法疗效的生物标志物

Casalegno Garduño, Rosaely; Spitschak, Alf; Pannek, Tim; Pützer, Brigitte M

E2F1-induced autocrine IL-6 inflammatory loop mediates cancer-immune crosstalk that predicts T cell phenotype switching and therapeutic responsiveness

E2F1诱导的自分泌IL-6炎症环路介导癌症-免疫串扰,从而预测T细胞表型转换和治疗反应性。

Alf Spitschak ,Prabir Dhar # ,Krishna P Singh # ,Rosaely Casalegno Garduño # ,Shailendra K Gupta ,Julio Vera ,Luca Musella ,Nico Murr ,Anja Stoll ,Brigitte M Pützer

Novel integrated workflow allows production and in-depth quality assessment of multifactorial reprogrammed skeletal muscle cells from human stem cells

新颖的集成工作流程允许从人类干细胞中生产多因素重编程骨骼肌细胞并进行深入的质量评估

Dinis Faustino, Heinrich Brinkmeier, Stella Logotheti, Anika Jonitz-Heincke, Hande Yilmaz, Isil Takan, Kirsten Peters, Rainer Bader, Hermann Lang, Athanasia Pavlopoulou, Brigitte M Pützer #, Alf Spitschak #

Drug Repurposing at the Interface of Melanoma Immunotherapy and Autoimmune Disease

黑色素瘤免疫疗法与自身免疫性疾病交叉领域的药物再利用

Spitschak, Alf; Gupta, Shailendra; Singh, Krishna P; Logotheti, Stella; Pützer, Brigitte M

Mechanisms of Functional Pleiotropy of p73 in Cancer and Beyond

p73在癌症及其他领域中功能多效性的机制

Logotheti, Stella; Richter, Christin; Murr, Nico; Spitschak, Alf; Marquardt, Stephan; Pützer, Brigitte M

LncRNA-SLC16A1-AS1 induces metabolic reprogramming during Bladder Cancer progression as target and co-activator of E2F1

LncRNA-SLC16A1-AS1作为E2F1的靶点和共激活因子,在膀胱癌进展过程中诱导代谢重编程。

Stella Logotheti ,Stephan Marquardt ,Shailendra K Gupta ,Christin Richter ,Berdien A H Edelhäuser ,David Engelmann ,Julia Brenmoehl ,Christoph Söhnchen ,Nico Murr ,Michael Alpers ,Krishna P Singh ,Olaf Wolkenhauer ,Dirk Heckl ,Alf Spitschak ,Brigitte M Pützer

Drug Repositioning Inferred from E2F1-Coregulator Interactions Studies for the Prevention and Treatment of Metastatic Cancers

从 E2F1-辅调节剂相互作用研究推断药物重新定位用于预防和治疗转移性癌症

Deborah Goody, Shailendra K Gupta, David Engelmann, Alf Spitschak, Stephan Marquardt, Stefan Mikkat, Claudia Meier, Charlotte Hauser, Jan-Paul Gundlach, Jan-Hendrik Egberts, Hubert Martin, Toni Schumacher, Anna Trauzold, Olaf Wolkenhauer, Stella Logotheti, Brigitte M Pützer

Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasiveness

通过 APLF 抑制将 E2F1 与经典 NHEJ 重新连接可促进膀胱癌侵袭性

Christin Richter, Stephan Marquardt, Fanghua Li, Alf Spitschak, Nico Murr, Berdien A H Edelhäuser, George Iliakis, Brigitte M Pützer, Stella Logotheti