日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mitochondrial oxidants promote platelet activation and thrombotic susceptibility in prediabetes

线粒体氧化剂促进血小板活化,增加糖尿病前期患者的血栓形成倾向

Ahmed, Azaj; Yadav, Pooja; Jensen, Melissa; Geasland, Katharine; Swamy, Jagadish; Spitz, Douglas R; Abel, E Dale; Jalal, Diana; Dayal, Sanjana

P7C3-A20 prevents whole brain radiotherapy-induced chronic hippocampal redox imbalance and neuropsychiatric impairment in mice

P7C3-A20可预防小鼠全脑放射治疗引起的慢性海马氧化还原失衡和神经精神损伤。

Vázquez-Rosa, Edwin; Shin, Min-Kyoo; Chaubey, Kalyani; Barker, Sarah; Corella, Sofia G; Chakraborty, Suwarna; Tripathi, Sunil Jamuna; Yu, Youngmin; Hyung, Jiwon; Dashora, Himanshu; Hao, Jing; Cintrón-Pérez, Coral J; Bud, Zea; Dhar, Matasha; Miller, Emiko; Koh, Yeojung; Lindley, Kate P; Indrakumar, Vidya; Rodriguez, Rocio Aguila; Mapuskar, Kranti A; Schoenfeld, Joshua D; Fujioka, Hisashi; Szweda, Luke I; Wilson, Brigid M; Yu, Jennifer S; Paul, Bindu D; Spitz, Douglas R; Allen, Bryan G; Pieper, Andrew A

Somatic CRISPR tumorigenesis and multiomic analysis reveal a pentose phosphate pathway disruption vulnerability in MPNSTs.

体细胞 CRISPR 致瘤性和多组学分析揭示了 MPNST 中磷酸戊糖途径破坏的脆弱性

McGivney Gavin R, Brockman Qierra R, Borcherding Nicholas, Scherer Amanda, Rauckhorst Adam J, Gutierrez Wade R, Solst Shane R, Heer Collin D, Warrier Akshaya, Floyd Warren, Kirsch David G, Knepper-Adrian Vickie L, Laverty Emily A, Roughton Grace A, Spitz Douglas R, Taylor Eric B, Dodd Rebecca D

Iron-oxide nanoparticles selectively enhance the toxicity of pharmacological ascorbate through hydrogen peroxide-dependent DNA damage in non-small cell lung cancer (NSCLC)

氧化铁纳米颗粒通过过氧化氢依赖性DNA损伤选择性地增强药理学抗坏血酸在非小细胞肺癌(NSCLC)中的毒性

Singhania, Mekhla; Sho, Sei; Fath, Melissa A; Sanchez, Adriana; Pulliam, Casey F; Allen, Bryan G; Buettner, Garry R; Goswami, Prabhat C; Spies, Maria; Petronek, Michael S; Spitz, Douglas R

Mitoregulin Promotes Cell Cycle Progression in Non-Small Cell Lung Cancer Cells.

线粒体调节蛋白促进非小细胞肺癌细胞的细胞周期进程

Stein Colleen S, Linzer Connor R, Heer Collin D, Witmer Nathan H, Cochran Jesse D, Spitz Douglas R, Boudreau Ryan L

Targeting CXCR4 with 212Pb/203Pb-Pentixather Significantly Increases Overall Survival in Small Cell Lung Cancer

使用 212Pb/203Pb-Pentixather 靶向 CXCR4 可显著提高小细胞肺癌患者的总生存期

Christensen, Keegan A; Fath, Melissa A; Ewald, Jordan T; Robles-Planells, Claudia; Graves, Stephen A; Johnson, Spenser S; Zacharias, Zeb R; Houtman, Jon C D; O'Dorisio, M Sue; Schultz, Michael K; Allen, Bryan G; Furqan, Muhammad; Menda, Yusuf; Liu, Dijie; Spitz, Douglas R

Additive Effects of Cu-ATSM and Radiation on Survival of Diffuse Intrinsic Pontine Glioma Cells

Cu-ATSM和辐射对弥漫性内生性脑桥胶质瘤细胞存活的叠加效应

King, Sarah A; Solst, Shane R; Graham, Claire H; Fiore, Lianna Z; Rheem, Rana; Tomanek-Chalkley, Ann; Fath, Melissa A; Caster, Joseph M; Spitz, Douglas R; Howard, Michelle E

Inhibiting sirtuin-dependent DNA repair and oxidative stress responses impairs DIPG cell survival.

抑制 sirtuin 依赖的 DNA 修复和氧化应激反应会损害 DIPG 细胞的存活。

King Sarah A, Rheem Rana, Spitler Kathryn M, O'Leary Brianne R, Graham Claire H, Solst Shane R, Teesch Lynn M, Sho Sei, Byrne James D, Spitz Douglas R, Howard Michelle E

FLASH: New intersection of physics, chemistry, biology, and cancer medicine

快讯:物理学、化学、生物学和癌症医学的新交叉领域

Vozenin, Marie-Catherine; Loo, Billy W Jr; Tantawi, Sami; Maxim, Peter G; Spitz, Douglas R; Bailat, Claude; Limoli, Charles L

Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance

组蛋白H3.1是一种染色质内嵌的氧化还原传感器,可被肿瘤细胞激活,从而产生适应性表型可塑性和多药耐药性。

Palma, Flavio R; Coelho, Diego R; Pulakanti, Kirthi; Sakiyama, Marcelo J; Huang, Yunping; Ogata, Fernando T; Danes, Jeanne M; Meyer, Alison; Furdui, Cristina M; Spitz, Douglas R; Gomes, Ana P; Gantner, Benjamin N; Rao, Sridhar; Backman, Vadim; Bonini, Marcelo G