Splinter Patrick L相关文献与解析，生知库

Victorelli, Stella; Eppard, Madeline; Martini, Hélène; Woo, Seung-Hwa; Everts, Stacia P A; Lee, Gung; Pirius, Nicholas; Han, Nuan; Liang, Eugene Y; Franco, Ana Catarina; Han, Yeaeun; Saul, Dominik; Nóvoa, Eva; Nogueiras, Rubén; Splinter, Patrick L; O'Hara, Steven P; Morgenthaler, Olivia; Valenzuela-Pérez, Lucía; Kim Lee, Hyun Se; Jurk, Diana; LaRusso, Nicholas F; Hirsova, Petra; Passos, João F

线粒体

发表日期：2025

文献求助收藏

Differential MYC Phosphorylation Drives the Divergent Cholangiocyte Response to Stress.

MYC 磷酸化差异驱动胆管细胞对压力的不同反应

期刊:Cellular and Molecular Gastroenterology and Hepatology

影响因子:7.4

doi:10.1016/j.jcmgh.2025.101547

O'Hara Steven P, Splinter Patrick L, Felzen Antonia, Turner Carys A, Morgenthaler Olivia T, Gores Gregory J, LaRusso Nicholas F

Macrophages contribute to the pathogenesis of sclerosing cholangitis in mice

巨噬细胞参与小鼠硬化性胆管炎的发病机制。

期刊:Journal of Hepatology

影响因子:33

doi:10.1016/j.jhep.2018.05.018

Guicciardi, Maria Eugenia; Trussoni, Christy E; Krishnan, Anuradha; Bronk, Steven F; Lorenzo Pisarello, Maria J; O'Hara, Steven P; Splinter, Patrick L; Gao, Yandong; Vig, Pamela; Revzin, Alexander; LaRusso, Nicholas F; Gores, Gregory J

Targeting senescent cholangiocytes and activated fibroblasts with B-cell lymphoma-extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2(-/-) ) mice.

使用 B 细胞淋巴瘤超大抑制剂靶向衰老胆管细胞和活化成纤维细胞，可改善多药耐药 2 基因敲除 (Mdr2(-/-) ) 小鼠的纤维化

期刊:Hepatology

影响因子:15.8

doi:10.1002/hep.29464

Moncsek Anja, Al-Suraih Mohammed S, Trussoni Christy E, O'Hara Steven P, Splinter Patrick L, Zuber Camille, Patsenker Eleonora, Valli Piero V, Fingas Christian D, Weber Achim, Zhu Yi, Tchkonia Tamar, Kirkland James L, Gores Gregory J, MÃ¼llhaupt Beat, LaRusso Nicholas F, Mertens Joachim C

Absence of the intestinal microbiota exacerbates hepatobiliary disease in a murine model of primary sclerosing cholangitis

在原发性硬化性胆管炎小鼠模型中，肠道菌群缺失会加剧肝胆疾病。

期刊:Hepatology

影响因子:15.8

doi:10.1002/hep.27927

Tabibian, James H; O'Hara, Steven P; Trussoni, Christy E; Tietz, Pamela S; Splinter, Patrick L; Mounajjed, Taofic; Hagey, Lee R; LaRusso, Nicholas F

Cholangiocyte senescence by way of N-ras activation is a characteristic of primary sclerosing cholangitis

胆管细胞通过 N-ras 激活而衰老是原发性硬化性胆管炎的特征之一。

期刊:Hepatology

影响因子:15.8

doi:10.1002/hep.26993

Tabibian, James H; O'Hara, Steven P; Splinter, Patrick L; Trussoni, Christy E; LaRusso, Nicholas F

Characterization of cultured cholangiocytes isolated from livers of patients with primary sclerosing cholangitis

对从原发性硬化性胆管炎患者肝脏中分离培养的胆管细胞进行表征

期刊:Laboratory Investigation

影响因子:4.2

doi:10.1038/labinvest.2014.94

Tabibian, James H; Trussoni, Christy E; O'Hara, Steven P; Splinter, Patrick L; Heimbach, Julie K; LaRusso, Nicholas F

细胞生物学

发表日期：2014

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The dynamic biliary epithelia: molecules, pathways, and disease

动态胆管上皮：分子、通路和疾病

期刊:Journal of Hepatology

影响因子:33

doi:10.1016/j.jhep.2012.10.011

O'Hara, Steven P; Tabibian, James H; Splinter, Patrick L; LaRusso, Nicholas F

信号转导

发表日期：2013

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Cholangiocyte myosin IIB is required for localized aggregation of sodium glucose cotransporter 1 to sites of Cryptosporidium parvum cellular invasion and facilitates parasite internalization

胆管细胞肌球蛋白IIB是钠-葡萄糖协同转运蛋白1在隐孢子虫细胞入侵部位局部聚集所必需的，并促进寄生虫的内化。

期刊:Infection and Immunity

影响因子:2.8

doi:10.1128/IAI.00077-10

O'Hara, Steven P; Gajdos, Gabriella B; Trussoni, Christy E; Splinter, Patrick L; LaRusso, Nicholas F

B7-H1 expression in vestibular schwannomas

前庭神经鞘瘤中B7-H1的表达

期刊:Otology & Neurotology

影响因子:2

doi:10.1097/MAO.0b013e3181e40e4f

Archibald, David J; Neff, Brian A; Voss, Stephen G; Splinter, Patrick L; Driscoll, Colin L W; Link, Michael J; Dong, Haidong; Kwon, Eugene D

Mitochondrial RNA cytosolic leakage drives the SASP

线粒体RNA胞质泄漏驱动SASP。

Differential MYC Phosphorylation Drives the Divergent Cholangiocyte Response to Stress.

MYC 磷酸化差异驱动胆管细胞对压力的不同反应

Macrophages contribute to the pathogenesis of sclerosing cholangitis in mice

巨噬细胞参与小鼠硬化性胆管炎的发病机制。

Targeting senescent cholangiocytes and activated fibroblasts with B-cell lymphoma-extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2(-/-) ) mice.

使用 B 细胞淋巴瘤超大抑制剂靶向衰老胆管细胞和活化成纤维细胞，可改善多药耐药 2 基因敲除 (Mdr2(-/-) ) 小鼠的纤维化

Absence of the intestinal microbiota exacerbates hepatobiliary disease in a murine model of primary sclerosing cholangitis

在原发性硬化性胆管炎小鼠模型中，肠道菌群缺失会加剧肝胆疾病。

Cholangiocyte senescence by way of N-ras activation is a characteristic of primary sclerosing cholangitis

胆管细胞通过 N-ras 激活而衰老是原发性硬化性胆管炎的特征之一。

Characterization of cultured cholangiocytes isolated from livers of patients with primary sclerosing cholangitis

对从原发性硬化性胆管炎患者肝脏中分离培养的胆管细胞进行表征

The dynamic biliary epithelia: molecules, pathways, and disease

动态胆管上皮：分子、通路和疾病

Cholangiocyte myosin IIB is required for localized aggregation of sodium glucose cotransporter 1 to sites of Cryptosporidium parvum cellular invasion and facilitates parasite internalization

胆管细胞肌球蛋白IIB是钠-葡萄糖协同转运蛋白1在隐孢子虫细胞入侵部位局部聚集所必需的，并促进寄生虫的内化。

B7-H1 expression in vestibular schwannomas

前庭神经鞘瘤中B7-H1的表达