日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Acquired cross-linker resistance associated with a novel spliced BRCA2 protein variant for molecular phenotyping of BRCA2 disruption.

获得性交联剂抗性与一种新型剪接 BRCA2 蛋白变体相关,用于 BRCA2 破坏的分子表型分析

Meyer Stefan, Stevens Adam, Paredes Roberto, Schneider Marion, Walker Michael J, Williamson Andrew J K, Gonzalez-Sanchez Maria-Belen, Smetsers Stephanie, Dalal Vineet, Teng Hsiang Ying, White Daniel J, Taylor Sam, Muter Joanne, Pierce Andrew, de Leonibus Chiara, Rockx Davy A P, Rooimans Martin A, Spooncer Elaine, Stauffer Stacey, Biswas Kajal, Godthelp Barbara, Dorsman Josephine, Clayton Peter E, Sharan Shyam K, Whetton Anthony D

Identification of nuclear protein targets for six leukemogenic tyrosine kinases governed by post-translational regulation

鉴定由翻译后调控控制的六种致白血病酪氨酸激酶的核蛋白靶点

Andrew Pierce, Andrew Williamson, Ewa Jaworska, John R Griffiths, Sam Taylor, Michael Walker, Mark Aspinall-O'Dea, Elaine Spooncer, Richard D Unwin, Toryn Poolman, David Ray, Anthony D Whetton

Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemia

急性髓系白血病小鼠模型中转录重编程的全基因组分析

Nicolas Bonadies, Samuel D Foster, Wai-In Chan, Brynn T Kvinlaug, Dominik Spensberger, Mark A Dawson, Elaine Spooncer, Anthony D Whetton, Andrew J Bannister, Brian J Huntly, Berthold Göttgens

THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo

THOC5/FMIP 是一种 mRNA 输出 TREX 复合蛋白,对体内造血原始细胞存活至关重要

Annalisa Mancini, Susanne C Niemann-Seyde, Rüdiger Pankow, Omar El Bounkari, Sabine Klebba-Färber, Alexandra Koch, Ewa Jaworska, Elaine Spooncer, Achim D Gruber, Anthony D Whetton, Teruko Tamura

An activated protein kinase C alpha gives a differentiation signal for hematopoietic progenitor cells and mimicks macrophage colony-stimulating factor-stimulated signaling events

活化的蛋白激酶Cα为造血祖细胞提供分化信号,并模拟巨噬细胞集落刺激因子刺激的信号事件。

Pierce, A; Heyworth, C M; Nicholls, S E; Spooncer, E; Dexter, T M; Lord, J M; Owen-Lynch, P J; Wark, G; Whetton, A D

The mouse M-lysozyme gene domain: identification of myeloid and differentiation specific DNasel hypersensitive sites and of a 3'-cis acting regulatory element

小鼠M溶菌酶基因结构域:髓系和分化特异性DNasel超敏位点以及3'-顺式作用调控元件的鉴定

Möllers, B; Klages, S; Wedel, A; Cross, M; Spooncer, E; Dexter, T M; Renkawitz, R

Immunoglobulin heavy-chain and CD3 delta-chain gene enhancers are DNase I-hypersensitive in hemopoietic progenitor cells

造血祖细胞中的免疫球蛋白重链和CD3δ链基因增强子对DNase I高度敏感。

Ford, A M; Bennett, C A; Healy, L E; Navarro, E; Spooncer, E; Greaves, M F

Rates of mutation to growth factor autonomy and tumorigenicity differ in hematopoietic stem and precursor cells expressing the multilineage colony-stimulating factor gene

表达多系集落刺激因子基因的造血干细胞和前体细胞中,生长因子自主性和致瘤性的突变率存在差异。

Laker, C; Kluge, N; Stocking, C; Just, U; Franz, M J; Ostertag, W; DeLamarter, J F; Dexter, M; Spooncer, E

Perturbed hemopoiesis and the generation of multipotential stem cell clones in src-infected bone marrow cultures is an indirect or transient effect of the oncogene

在感染Src基因的骨髓培养物中,造血功能紊乱和多能干细胞克隆的产生是该癌基因的间接或短暂效应。

Wyke, J A; Stoker, A W; Searle, S; Spooncer, E; Simmons, P; Dexter, T M