日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cryo-EM structures of Nipah virus polymerases and high-throughput RdRp assay development enable anti-NiV drug discovery.

尼帕病毒聚合酶的冷冻电镜结构和高通量 RdRp 检测方法的开发,为抗尼帕病毒药物的发现提供了可能

Chen Zhenhang, Quirit Dudley Jeanne, Deniston Colin, Buffalo Cosmo Z, Patra Debjani, Cao Dongdong, Hunt Julia, Rohaim Ahmed, Sengupta Debapriya, Wen Lan, Tsang Tiffany, Xie Lili, DiDonato Michael, Spraggon Glen, Clifton Matthew C, Jarrousse Nadine, Straimer Judith, Liang Bo

Crystal structure of a two-subunit TrkA octameric gating ring assembly

双亚基TrkA八聚体门控环组装体的晶体结构

Deller, Marc C; Johnson, Hope A; Miller, Mitchell D; Spraggon, Glen; Elsliger, Marc-André; Wilson, Ian A; Lesley, Scott A

Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824

结核分枝杆菌中参与 PA-824 生物还原活化的脱氮黄素依赖性硝基还原酶 Ddn 的结构

Cellitti, Susan E; Shaffer, Jennifer; Jones, David H; Mukherjee, Tathagata; Gurumurthy, Meera; Bursulaya, Badry; Boshoff, Helena I; Choi, Inhee; Nayyar, Amit; Lee, Yong Sok; Cherian, Joseph; Niyomrattanakit, Pornwaratt; Dick, Thomas; Manjunatha, Ujjini H; Barry, Clifton E 3rd; Spraggon, Glen; Geierstanger, Bernhard H

On the use of DXMS to produce more crystallizable proteins: structures of the T. maritima proteins TM0160 and TM1171

利用DXMS制备更多可结晶蛋白质:海洋嗜热菌TM0160和TM1171蛋白的结构

Spraggon, Glen; Pantazatos, Dennis; Klock, Heath E; Wilson, Ian A; Woods, Virgil L Jr; Lesley, Scott A

Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline

利用高通量结构测定流程对海洋热袍菌(Thermotoga maritima)蛋白质组进行结构基因组学分析

Lesley, Scott A; Kuhn, Peter; Godzik, Adam; Deacon, Ashley M; Mathews, Irimpan; Kreusch, Andreas; Spraggon, Glen; Klock, Heath E; McMullan, Daniel; Shin, Tanya; Vincent, Juli; Robb, Alyssa; Brinen, Linda S; Miller, Mitchell D; McPhillips, Timothy M; Miller, Mark A; Scheibe, Daniel; Canaves, Jaume M; Guda, Chittibabu; Jaroszewski, Lukasz; Selby, Thomas L; Elsliger, Marc-Andre; Wooley, John; Taylor, Susan S; Hodgson, Keith O; Wilson, Ian A; Schultz, Peter G; Stevens, Raymond C