日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

On the Discorhabdins Leading to the Aleutianamine Ring System: A One-Step in Situ Transformation Characterized Through Computational and Experimental Studies and Its Implications on Biosynthesis, Synthesis, and Pharmacology

关于Discorhabdins通往Aleutianamine环系的转化：通过计算和实验研究表征的一步原位转化及其对生物合成、合成和药理学的影响

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.7864883
Dickinson, Cody F; Potluri, Abhay; Bland, Alison M; Flipse, Samuel M; Hanna, George S; Wagner, Ryan T; Robertson, Keith D; Ho, Thai H; Sprague, Daniel J; Hoff, Gerald R; Stone, Robert P; Tius, Marcus A; Tantillo, Dean J; Hamann, Mark T
发表日期：2026
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Meclonazepam sensitivity of parasitic flatworms correlates with TRPM(MCLZ) sensitivity to meclonazepam

寄生扁形动物对美氯硝西泮的敏感性与TRPM(MCLZ)对美氯硝西泮的敏感性相关

期刊:International Journal for Parasitology-Drugs and Drug Resistance
影响因子:3.4
doi:10.1016/j.ijpddr.2026.100634
Rohr, Claudia M; McCusker, Paul; Kaethner, Marc; Armstrong, Rebecca; Robb, Emily; Park, Sang-Kyu; Sprague, Daniel J; Maule, Aaron G; Zamanian, Mostafa; Lundström-Stadelmann, Britta; Chan, John D; Marchant, Jonathan S
发表日期：2026
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Target-Based Design of Praziquantel Analogs at Cestode TRPM(PZQ)

基于靶点的吡喹酮类似物设计（针对绦虫 TRPM(PZQ)）

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.5c00449
Sprague, Daniel J; Park, Sang-Kyu; Kaethner, Marc; Rohr, Claudia M; Ghobrial, Mina R; Barth, D Connor; Maillard, David; Spangenberg, Thomas; Lundström-Stadelmann, Britta; Marchant, Jonathan S
发表日期：2025
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Target-based discovery of a broad-spectrum flukicide.

基于靶点的广谱杀吸虫剂的发现

期刊:Nature Structural & Molecular Biology
影响因子:10.1
doi:10.1038/s41594-024-01298-3
Sprague Daniel J, Park Sang-Kyu, Gramberg Svenja, Bauer Lisa, Rohr Claudia M, Chulkov Evgeny G, Smith Emery, Scampavia Louis, Spicer Timothy P, Haeberlein Simone, Marchant Jonathan S
发表日期：2024
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The anthelmintic meclonazepam activates a schistosome transient receptor potential channel

驱虫药美氯硝西泮可激活血吸虫瞬时受体电位通道。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2023.105528
Park, Sang-Kyu; Sprague, Daniel J; Rohr, Claudia M; Chulkov, Evgeny G; Petrow, Ian; Kumar, Sushil; Marchant, Jonathan S
信号转导
发表日期：2024
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The TRIM33 Bromodomain Recognizes Histone Lysine Lactylation

TRIM33溴结构域识别组蛋白赖氨酸乳酸化

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.4c00248
Nuñez, Raymundo; Sidlowski, Paul F W; Steen, Erica A; Wynia-Smith, Sarah L; Sprague, Daniel J; Keyes, Robert F; Smith, Brian C
乳酸化
发表日期：2024
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Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types.

锌螯合BET溴结构域抑制剂同样靶向胰岛内分泌细胞类型

期刊:American Journal of Physiology-Regulatory Integrative and Comparative Physiology
影响因子:2.3
doi:10.1152/ajpregu.00259.2023
Jones Lipinski Rachel A, Stancill Jennifer S, Nuñez Raymundo, Wynia-Smith Sarah L, Sprague Daniel J, Nord Joshua A, Bird Amir, Corbett John A, Smith Brian C
细胞生物学
发表日期：2024
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TRP drop, TRP drop: a steady patter of anti-schistosomal target illumination

TRP下降，TRP下降：抗血吸虫靶标照明的稳定模式

期刊:Frontiers in Parasitology
影响因子:
doi:10.3389/fpara.2024.1349623
Sprague, Daniel J; Rohr, Claudia M; Marchant, Jonathan S
发表日期：2024
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Natural variation in the binding pocket of a parasitic flatworm TRPM channel resolves the basis for praziquantel sensitivity.

寄生扁形动物 TRPM 通道结合口袋的自然变异揭示了吡喹酮敏感性的基础

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2217732120
Rohr Claudia M, Sprague Daniel J, Park Sang-Kyu, Malcolm Nicholas J, Marchant Jonathan S
发表日期：2023
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The Anthelmintic Activity of Praziquantel Analogs Correlates with Structure-Activity Relationships at TRPM(PZQ) Orthologs

吡喹酮类似物的驱虫活性与TRPM(PZQ)同源物的构效关系相关

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.3c00350
Sprague, Daniel J; Kaethner, Marc; Park, Sang-Kyu; Rohr, Claudia M; Harris, Jade L; Maillard, David; Spangenberg, Thomas; Lundström-Stadelmann, Britta; Marchant, Jonathan S
发表日期：2023
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