日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A 107 Gene Nanostring Assay Effectively Translates the Cancer Genome Atlas, and Tumour Microenvironment Gastric Cancer Molecular Classification to a Patient-Derived Organoid Model.

107 基因纳米串分析有效地将癌症基因组图谱和肿瘤微环境胃癌分子分类转化为患者来源的类器官模型。

Skubleny D, Purich K, Williams T, McLean D R, Martins-Filho S N, Buttenschoen K, Haase E, McCall M, Baker K, Ghosh S, Spratlin J L, Schiller D E, Rayat G R

A phase 2, multicenter, open-label study of anti-LAG-3 ieramilimab in combination with anti-PD-1 spartalizumab in patients with advanced solid malignancies

一项针对晚期实体恶性肿瘤患者的 II 期、多中心、开放标签研究,评估抗 LAG-3 抗体 ieramilimab 联合抗 PD-1 抗体 spartalizumab 的疗效。

Lin, Chia-Chi; Garralda, Elena; Schöffski, Patrick; Hong, David S; Siu, Lillian L; Martin, Miguel; Maur, Michela; Hui, Rina; Soo, Ross A; Chiu, Joanne; Zhang, Tian; Ma, Brigette; Kyi, Chrisann; Tan, Daniel Sw; Cassier, Philippe A; Sarantopoulos, John; Weickhardt, Andrew; Carvajal, Richard D; Spratlin, Jennifer; Esaki, Taito; Rolland, Fréderic; Akerley, Wallace; Deschler-Baier, Barbara; Rispoli, Lawrence; Samant, Tanay S; Chowdhury, Niladri Roy; Gusenleitner, Daniel; Kwak, Eunice L; Askoxylakis, Vasileios; De Braud, Filippo

Individual Survival Distributions Generated by Multi-Task Logistic Regression Yield a New Perspective on Molecular and Clinical Prognostic Factors in Gastric Adenocarcinoma

多任务逻辑回归生成的个体生存分布为胃腺癌的分子和临床预后因素提供了新的视角

Skubleny, Daniel; Spratlin, Jennifer; Ghosh, Sunita; Greiner, Russell; Schiller, Daniel E; Rayat, Gina R

Feature-specific quantile normalization and feature-specific mean-variance normalization deliver robust bi-directional classification and feature selection performance between microarray and RNAseq data

特征特异性分位数归一化和特征特异性均值-方差归一化可在微阵列和RNA测序数据之间实现稳健的双向分类和特征选择性能。

Skubleny, Daniel; Ghosh, Sunita; Spratlin, Jennifer; Schiller, Daniel E; Rayat, Gina R

A first-in-human phase I trial of daily oral zelenirstat, a N-myristoyltransferase inhibitor, in patients with advanced solid tumors and relapsed/refractory B-cell lymphomas

一项针对晚期实体瘤和复发/难治性B细胞淋巴瘤患者的每日口服泽利尼司他(一种N-肉豆蔻酰转移酶抑制剂)的首次人体I期试验

Sangha, Randeep; Jamal, Rahima; Spratlin, Jennifer; Kuruvilla, John; Sehn, Laurie H; Beauchamp, Erwan; Weickert, Michael; Berthiaume, Luc G; Mackey, John R

Murine and Human Gastric Tissue Establishes Organoids after 48 Hours of Cold Ischemia Time during Shipment

小鼠和人类胃组织在运输过程中经过 48 小时的冷缺血后形成类器官

Daniel Skubleny, Saurabh Garg, Jim Wickware, Kieran Purich, Sunita Ghosh, Jennifer Spratlin, Dan E Schiller, Gina R Rayat

Increased CD4/CD8 Lymphocyte ratio predicts favourable neoadjuvant treatment response in gastric cancer: A prospective pilot study

CD4/CD8 淋巴细胞比率升高可预测胃癌新辅助治疗反应良好:一项前瞻性试点研究

Daniel Skubleny, Andrea Lin, Saurabh Garg, Ross McLean, Michael McCall, Sunita Ghosh, Jennifer L Spratlin, Daniel Schiller, Gina Rayat

Novel, First-in-Human, Oral PCLX-001 Treatment in a Patient with Relapsed Diffuse Large B-Cell Lymphoma

首次在人体上使用的新型口服 PCLX-001 疗法治疗复发性弥漫大 B 细胞淋巴瘤患者

Randeep Sangha, Neal M Davies, Afshin Namdar, Michael Chu, Jennifer Spratlin, Erwan Beauchamp, Luc G Berthiaume, John R Mackey

Real-world treatment patterns, clinical outcomes, and health care resource utilization in advanced unresectable hepatocellular carcinoma

晚期不可切除肝细胞癌的真实世界治疗模式、临床结果和医疗资源利用情况

O'Sullivan, Dylan E; Boyne, Devon J; Syed, Iqra A; Shephard, Cal; Clouthier, Derek L; Yoshida, Eric M; Spratlin, Jennifer L; Batra, Atul; Rigo, Rodrigo; Hannouf, Malek; Yang Hu, Xun; N Jarada, Tamer; Brenner, Darren R; Cheung, Winson Y

A Population-Based Retrospective Study of Biliary Tract Cancers in Alberta, Canada

加拿大艾伯塔省胆道癌的一项基于人群的回顾性研究

Beaulieu, Carissa; Lui, Arthur; Yusuf, Dimas; Abdelaziz, Zainab; Randolph, Brock; Batuyong, Eugene; Ghosh, Sunita; Bathe, Oliver F; Tam, Vincent; Spratlin, Jennifer L