日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Translesion-synthesis-mediated bypass of DNA lesions occurs predominantly behind replication forks restarted by PrimPol.

跨损伤合成介导的 DNA 损伤绕过主要发生在由 PrimPol 重新启动的复制叉之后

期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2025.115360
Dhoonmoon Ashna, Ambrose Julia R, Garg Sonal, Lascarez-Espana Cynthia, Rebok Abbey, Spratt Thomas E, Moldovan George-Lucian, Nicolae Claudia M
毒理研究
发表日期：2025
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N(2) -Substituted 2'-Deoxyguanosine Triphosphate Derivatives as Selective Substrates for Human DNA Polymerase κ

N(2)-取代的2'-脱氧鸟苷三磷酸衍生物作为人DNA聚合酶κ的选择性底物

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.201611607
Gowda, A S Prakasha; Lee, Marietta; Spratt, Thomas E
Human
发表日期：2017
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Honokiol Inhibits DNA Polymerases β and λ and Increases Bleomycin Sensitivity of Human Cancer Cells

厚朴酚抑制DNA聚合酶β和λ，并提高人类癌细胞对博来霉素的敏感性

期刊:Chemical Research in Toxicology
影响因子:3.8
doi:10.1021/acs.chemrestox.6b00451
Gowda, A S Prakasha; Suo, Zucai; Spratt, Thomas E
Human
细胞生物学
肿瘤
肿瘤免疫
发表日期：2017
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Mutagenic Replication of N(2)-Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase I and Sulfolobus solfataricus DNA Polymerase IV

大肠杆菌DNA聚合酶I和硫磺叶菌DNA聚合酶IV对N(2)-脱氧鸟苷苯并[a]芘加合物的诱变复制

期刊:Chemical Research in Toxicology
影响因子:3.8
doi:10.1021/acs.chemrestox.6b00466
Gowda, A S Prakasha; Krzeminski, Jacek; Amin, Shantu; Suo, Zucai; Spratt, Thomas E
发表日期：2017
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Active Site Interactions Impact Phosphoryl Transfer during Replication of Damaged and Undamaged DNA by Escherichia coli DNA Polymerase I

活性位点相互作用影响大肠杆菌DNA聚合酶I复制受损和未受损DNA过程中的磷酸转移

期刊:Chemical Research in Toxicology
影响因子:3.8
doi:10.1021/acs.chemrestox.7b00257
Prakasha Gowda, A S; Spratt, Thomas E
发表日期：2017
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DNA Polymerases η and ζ Combine to Bypass O(2)-[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Formed from Tobacco Carcinogens

DNA聚合酶η和ζ结合以绕过O(2)-[4-(3-吡啶基)-4-氧代丁基]胸腺嘧啶，这是一种由烟草致癌物形成的DNA加合物

期刊:Chemical Research in Toxicology
影响因子:3.8
doi:10.1021/acs.chemrestox.5b00468
Gowda, A S Prakasha; Spratt, Thomas E
肿瘤
肿瘤免疫
发表日期：2016
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DNA Polymerase ν Rapidly Bypasses O(6)-Methyl-dG but Not O(6)-[4-(3-Pyridyl)-4-oxobutyl-dG and O(2)-Alkyl-dTs

DNA聚合酶ν能快速绕过O(6)-甲基-dG，但不能绕过O(6)-[4-(3-吡啶基)-4-氧代丁基-dG和O(2)-烷基-dTs。

期刊:Chemical Research in Toxicology
影响因子:3.8
doi:10.1021/acs.chemrestox.6b00318
Gowda, A S Prakasha; Spratt, Thomas E
发表日期：2016
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Tobacco-specific nitrosamine-derived O2-alkylthymidines are potent mutagenic lesions in SOS-induced Escherichia coli

烟草特异性亚硝胺衍生的O2-烷基胸苷是SOS诱导的大肠杆菌中的强效诱变损伤。

期刊:Chemical Research in Toxicology
影响因子:3.8
doi:10.1021/tx200435d
Jasti, Vijay P; Spratt, Thomas E; Basu, Ashis K
发表日期：2011
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Facile syntheses of O(2)-[4-(3-pyridyl-4-oxobut-1-yl]thymidine, the major adduct formed by tobacco specific nitrosamine 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in vivo, and its site-specifically adducted oligodeoxynucleotides

简便合成 O(2)-[4-(3-吡啶基-4-氧代丁-1-基]胸苷，它是烟草特异性亚硝胺 4-甲基亚硝胺-1-(3-吡啶基)-1-丁酮 (NNK) 在体内形成的主要加合物，以及其位点特异性加合的寡脱氧核苷酸

期刊:Chemical Research in Toxicology
影响因子:3.8
doi:10.1021/tx200127j
Krishnegowda, Gowdahalli; Sharma, Arun K; Krzeminski, Jacek; Gowda, A S Prakasha; Lin, Jyh-Ming; Desai, Dhimant; Spratt, Thomas E; Amin, Shantu
发表日期：2011
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Characterization of dibenzo[a,l]pyrene-trans-11,12-diol (dibenzo[def,p]chrysene) glucuronidation by UDP-glucuronosyltransferases

UDP-葡萄糖醛酸转移酶对二苯并[a,l]芘-反式-11,12-二醇（二苯并[def,p]屈）葡萄糖醛酸化的表征

期刊:Chemical Research in Toxicology
影响因子:3.8
doi:10.1021/tx200178v
Olson, Kristine C; Sun, Dongxiao; Chen, Gang; Sharma, Arun K; Amin, Shantu; Ropson, Ira J; Spratt, Thomas E; Lazarus, Philip
发表日期：2011
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