日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties.

从头设计整合素α5β1调节蛋白以增强生物材料性能

Wang Xinru, Guillem-Marti Jordi, Kumar Saurav, Lee David S, Cabrerizo-Aguado Daniel, Werther Rachel, Alamo Kevin Alexander Estrada, Zhao Yan Ting, Nguyen Adam, Kopyeva Irina, Huang Buwei, Li Jing, Hao Yuxin, Li Xinting, Brizuela-Velasco Aritza, Murray Analisa, Gerben Stacey, Roy Anindya, DeForest Cole A, Springer Timothy, Ruohola-Baker Hannele, Cooper Jonathan A, Campbell Melody G, Manero Jose Maria, Ginebra Maria-Pau, Baker David

Structural insights into MIC2 recognition by MIC2-associated protein in Toxoplasma gondii

弓形虫中MIC2相关蛋白识别MIC2的结构解析

Zhang, Su; Wang, Fangfang; Zhang, Dujuan; Liu, Dongsheng; Ding, Wei; Springer, Timothy A; Song, Gaojie

De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8

从头设计高选择性整合素αvβ6和αvβ8小蛋白抑制剂

Roy, Anindya; Shi, Lei; Chang, Ashley; Dong, Xianchi; Fernandez, Andres; Kraft, John C; Li, Jing; Le, Viet Q; Winegar, Rebecca Viazzo; Cherf, Gerald Maxwell; Slocum, Dean; Daniel Poulson, P; Casper, Garrett E; Vallecillo-Zúniga, Mary L; Valdoz, Jonard Corpuz; Miranda, Marcos C; Bai, Hua; Kipnis, Yakov; Olshefsky, Audrey; Priya, Tanu; Carter, Lauren; Ravichandran, Rashmi; Chow, Cameron M; Johnson, Max R; Cheng, Suna; Smith, McKaela; Overed-Sayer, Catherine; Finch, Donna K; Lowe, David; Bera, Asim K; Matute-Bello, Gustavo; Birkland, Timothy P; DiMaio, Frank; Raghu, Ganesh; Cochran, Jennifer R; Stewart, Lance J; Campbell, Melody G; Van Ry, Pam M; Springer, Timothy; Baker, David

Structures of VWF tubules before and after concatemerization reveal a mechanism of disulfide bond exchange

VWF小管在串联化前后的结构揭示了二硫键交换的机制

Anderson, Jacob R; Li, Jing; Springer, Timothy A; Brown, Alan

Conformation of von Willebrand factor in shear flow revealed with stroboscopic single-molecule imaging

利用频闪单分子成像技术揭示剪切流中血管性血友病因子构象

Bergal, Hans T; Jiang, Yan; Yang, Darren; Springer, Timothy A; Wong, Wesley P

Monomeric prefusion structure of an extremophile gamete fusogen and stepwise formation of the postfusion trimeric state

极端微生物配子融合蛋白的单体融合前结构及融合后三聚体状态的逐步形成

Feng, Juan; Dong, Xianchi; Su, Yang; Lu, Chafen; Springer, Timothy A

Congenital X-linked neutropenia with myelodysplasia and somatic tetraploidy due to a germline mutation in SEPT6

由SEPT6基因种系突变引起的先天性X连锁中性粒细胞减少症伴骨髓增生异常综合征和体细胞四倍体

Renella, Raffaele; Gagne, Katelyn; Beauchamp, Ellen; Fogel, Jonathan; Perlov, Aleksej; Sola, Mireia; Schlaeger, Thorsten; Hofmann, Inga; Shimamura, Akiko; Ebert, Benjamin L; Schmitz-Abe, Klaus; Markianos, Kyriacos; Murphy, Kristi; Sun, Liang; Rockowitz, Shira; Sliz, Piotr; Campagna, Dean R; Springer, Timothy A; Bahl, Christopher; Agarwal, Suneet; Fleming, Mark D; Williams, David A

Von Willebrand factor A1 domain stability and affinity for GPIbα are differentially regulated by its O-glycosylated N- and C-linker

血管性血友病因子A1结构域的稳定性和对GPIbα的亲和力受其O-糖基化的N-和C-连接肽的差异性调控。

Bonazza, Klaus; Iacob, Roxana E; Hudson, Nathan E; Li, Jing; Lu, Chafen; Engen, John R; Springer, Timothy A

Protection of the Prodomain α1-Helix Correlates with Latency in the Transforming Growth Factor-β Family

前结构域α1螺旋的保护与转化生长因子-β家族的潜伏期相关

Le, Viet Q; Iacob, Roxana E; Zhao, Bo; Su, Yang; Tian, Yuan; Toohey, Cameron; Engen, John R; Springer, Timothy A

Dynamics of integrin α5β1, fibronectin, and their complex reveal sites of interaction and conformational change

整合素α5β1、纤连蛋白及其复合物的动态变化揭示了相互作用位点和构象变化

Su, Yang; Iacob, Roxana E; Li, Jing; Engen, John R; Springer, Timothy A