Srikumar Chellappan相关文献与解析，生知库

Sathya Neelature Sriramareddy, Fernanda Faião-Flores, Michael F Emmons, Biswarup Saha, Srikumar Chellappan, Clayton Wyatt, Inna Smalley, Jonathan D Licht, Michael A Durante, J William Harbour, Keiran S M Smalley

肿瘤

黑色素瘤

发表日期：2022

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A Novel PHD2/VHL-mediated Regulation of YAP1 Contributes to VEGF Expression and Angiogenesis

PHD2/VHL 介导的 YAP1 新型调控有助于 VEGF 表达和血管生成

期刊:Cancer Research Communications

影响因子:2

doi:10.1158/2767-9764.crc-21-0084

Namrata Bora-Singhal, Biswarup Saha, Durairaj Mohankumar, Jaya Padmanabhan, Domenico Coppola, Srikumar Chellappan

Inhibitors Targeting CDK9 Show High Efficacy against Osimertinib and AMG510 Resistant Lung Adenocarcinoma Cells

针对 CDK9 的抑制剂对奥希替尼和 AMG510 耐药肺腺癌细胞表现出高效作用

期刊:Cancers

影响因子:

doi:10.3390/cancers13153906

Jaya Padmanabhan, Biswarup Saha, Chase Powell, Qianxing Mo, Bradford A Perez, Srikumar Chellappan

Novel HDAC11 inhibitors suppress lung adenocarcinoma stem cell self-renewal and overcome drug resistance by suppressing Sox2

新型 HDAC11 抑制剂通过抑制 Sox2 抑制肺腺癌干细胞自我更新并克服耐药性

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-020-61295-6

Namrata Bora-Singhal, Durairaj Mohankumar, Biswarup Saha, Christelle M Colin, Jennifer Y Lee, Matthew W Martin, Xiaozhang Zheng, Domenico Coppola, Srikumar Chellappan

Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC

Fendiline 通过抑制促肿瘤信号事件增强治疗药物对 PDAC 细胞的细胞毒性作用：一种对抗 PDAC 的潜在策略

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms20102423

Marwa Alhothali, Mevin Mathew, Geeta Iyer, Harshani R Lawrence, Shengyu Yang, Srikumar Chellappan, Jaya Padmanabhan

Nicotine-Mediated Regulation of Nicotinic Acetylcholine Receptors in Non-Small Cell Lung Adenocarcinoma by E2F1 and STAT1 Transcription Factors

尼古丁介导的 E2F1 和 STAT1 转录因子对非小细胞肺腺癌中烟碱乙酰胆碱受体的调节

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0156451

Courtney Schaal, Srikumar Chellappan

Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis

罐结合激酶 1 是微管动力学和有丝分裂所必需的着丝粒相关激酶

期刊:Nature Communications

影响因子:14.7

doi:10.1038/ncomms10072

Smitha Pillai, Jonathan Nguyen, Joseph Johnson, Eric Haura, Domenico Coppola, Srikumar Chellappan

信号转导

发表日期：2015

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β-arrestin-1 mediates nicotine-induced metastasis through E2F1 target genes that modulate epithelial-mesenchymal transition

β-arrestin-1 通过调节上皮-间质转化的 E2F1 靶基因介导尼古丁诱导的转移

期刊:Cancer Research

影响因子:12.5

doi:10.1158/0008-5472.CAN-14-0681

Smitha Pillai, Jose Trevino, Bhupendra Rawal, Sandeep Singh, Michelle Kovacs, Xueli Li, Michael Schell, Eric Haura, Gerold Bepler, Srikumar Chellappan

E2F1

发表日期：2015

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Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and β-catenin signaling

芬地林通过干扰 ADAM10 活化和 β-catenin 信号传导抑制胰腺癌细胞的增殖和侵袭

期刊:Oncotarget

影响因子:

doi:10.18632/oncotarget.5933

Neha Woods, Jose Trevino, Domenico Coppola, Srikumar Chellappan, Shengyu Yang, Jaya Padmanabhan

Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer

Gli1 介导的 Sox2 调节促进干细胞样细胞的自我更新并赋予非小细胞肺癌对 EGFR 抑制剂的耐药性

期刊:Neoplasia

影响因子:

doi:10.1016/j.neo.2015.07.001

Namrata Bora-Singhal, Deepak Perumal, Jonathan Nguyen, Srikumar Chellappan

HDAC11 activity contributes to MEK inhibitor escape in uveal melanoma

HDAC11 活性有助于 MEK 抑制剂在葡萄膜黑色素瘤中的逃逸

A Novel PHD2/VHL-mediated Regulation of YAP1 Contributes to VEGF Expression and Angiogenesis

PHD2/VHL 介导的 YAP1 新型调控有助于 VEGF 表达和血管生成

Inhibitors Targeting CDK9 Show High Efficacy against Osimertinib and AMG510 Resistant Lung Adenocarcinoma Cells

针对 CDK9 的抑制剂对奥希替尼和 AMG510 耐药肺腺癌细胞表现出高效作用

Novel HDAC11 inhibitors suppress lung adenocarcinoma stem cell self-renewal and overcome drug resistance by suppressing Sox2

新型 HDAC11 抑制剂通过抑制 Sox2 抑制肺腺癌干细胞自我更新并克服耐药性

Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC

Fendiline 通过抑制促肿瘤信号事件增强治疗药物对 PDAC 细胞的细胞毒性作用：一种对抗 PDAC 的潜在策略

Nicotine-Mediated Regulation of Nicotinic Acetylcholine Receptors in Non-Small Cell Lung Adenocarcinoma by E2F1 and STAT1 Transcription Factors

尼古丁介导的 E2F1 和 STAT1 转录因子对非小细胞肺腺癌中烟碱乙酰胆碱受体的调节

Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis

罐结合激酶 1 是微管动力学和有丝分裂所必需的着丝粒相关激酶

β-arrestin-1 mediates nicotine-induced metastasis through E2F1 target genes that modulate epithelial-mesenchymal transition

β-arrestin-1 通过调节上皮-间质转化的 E2F1 靶基因介导尼古丁诱导的转移

Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and β-catenin signaling

芬地林通过干扰 ADAM10 活化和 β-catenin 信号传导抑制胰腺癌细胞的增殖和侵袭

Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer

Gli1 介导的 Sox2 调节促进干细胞样细胞的自我更新并赋予非小细胞肺癌对 EGFR 抑制剂的耐药性