日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Immunotherapy targeting a leader sequence cathepsin G-derived peptide.

针对组织蛋白酶 G 衍生肽的前导序列的免疫疗法

Shi Chunhua, Tian Ze, Yan Jun, Zhang Mao, Sukhumalchandra Pariya, Chang Edward, Yang Guojun, You Junping, Cui Meng, Shi Qing, Kerros Celine, Philips Anne, Qiao Na, Torikai Hiroki, Patchametla Sathvik, Sergeeva Anna, St John Lisa, He Helen, Wiederschain Dmitri, Lee Benjamin H, Paulus Geraldine L C, Zha Dongxing, Molldrem Jeffrey, Alatrash Gheath

Hu8F4-CAR T cells with mutated Fc spacer segment improve target-specificity and mediate anti-leukemia activity in vivo

携带突变Fc间隔区段的Hu8F4-CAR T细胞可提高靶向特异性,并在体内发挥抗白血病活性。

Molldrem, Jeffrey; He, Hong; Vedia, Rolando; Lu, Sijie; Li, Qiaochuan; Cox, Kathryn; St John, Lisa; Sergeeva, Anna; Clise-Dwyer, Karen; Alatrash, Gheath; Shpall, Elizabeth; Ma, Qing

Novel myeloperoxidase-derived HLA-A2-restricted peptides as therapeutic targets against myeloid leukemia

新型髓过氧化物酶衍生的HLA-A2限制性肽作为治疗髓系白血病的靶点

Lu, Sijie; Tallis, Eran; Ding, Xiaoling; Li, Dan; Cox, Kathryn; You, M James; St John, Lisa; Alatrash, Gheath; Ma, Qing; Molldrem, Jeffrey J

Two unique HLA-A*0201 restricted peptides derived from cyclin E as immunotherapeutic targets in leukemia

两种源自细胞周期蛋白E的独特HLA-A*0201限制性肽作为白血病免疫治疗靶点

He, Hong; Kondo, Yukio; Ishiyama, Ken; Alatrash, Gheath; Lu, Sijie; Cox, Kathryn; Qiao, Na; Clise-Dwyer, Karen; St John, Lisa; Sukhumalchandra, Pariya; Ma, Qing; Molldrem, Jeffrey J

A Novel T-Cell Engaging Bi-specific Antibody Targeting the Leukemia Antigen PR1/HLA-A2

靶向白血病抗原PR1/HLA-A2的新型T细胞结合双特异性抗体

Herrmann, Amanda C; Im, Jin S; Pareek, Sumedha; Ruiz-Vasquez, Wilfredo; Lu, Sijie; Sergeeva, Anna; Mehrens, Jennifer; He, Hong; Alatrash, Gheath; Sukhumalchandra, Pariya; St John, Lisa; Clise-Dwyer, Karen; Zha, Dongxing; Molldrem, Jeffrey J

Serine Proteases Enhance Immunogenic Antigen Presentation on Lung Cancer Cells

丝氨酸蛋白酶增强肺癌细胞上的免疫原性抗原呈递

Peters, Haley L; Tripathi, Satyendra C; Kerros, Celine; Katayama, Hiroyuki; Garber, Haven R; St John, Lisa S; Federico, Lorenzo; Meraz, Ismail M; Roth, Jack A; Sepesi, Boris; Majidi, Mourad; Ruisaard, Kathryn; Clise-Dwyer, Karen; Roszik, Jason; Gibbons, Don L; Heymach, John V; Swisher, Stephen G; Bernatchez, Chantale; Alatrash, Gheath; Hanash, Samir; Molldrem, Jeffrey J

Decreases in thymopoiesis of astronauts returning from space flight

宇航员从太空飞行返回后胸腺造血功能下降

Benjamin, Cara L; Stowe, Raymond P; St John, Lisa; Sams, Clarence F; Mehta, Satish K; Crucian, Brian E; Pierson, Duane L; Komanduri, Krishna V

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy

BMP诱导的同源盒基因MIXL1在急性髓系白血病中的作用以及I型BMP受体作为潜在治疗靶点的鉴定

Raymond, Aaron; Liu, Bin; Liang, Hong; Wei, Caimiao; Guindani, Michele; Lu, Yue; Liang, Shoudan; St John, Lisa S; Molldrem, Jeff; Nagarajan, Lalitha

A novel HLA-A*0201 restricted peptide derived from cathepsin G is an effective immunotherapeutic target in acute myeloid leukemia

源自组织蛋白酶G的新型HLA-A*0201限制性肽是急性髓系白血病的一种有效免疫治疗靶点。

Zhang, Mao; Sukhumalchandra, Pariya; Enyenihi, Atim A; St John, Lisa S; Hunsucker, Sally A; Mittendorf, Elizabeth A; Sergeeva, Anna; Ruisaard, Kathryn; Al-Atrache, Zein; Ropp, Patricia A; Jakher, Haroon; Rodriguez-Cruz, Tania; Lizee, Gregory; Clise-Dwyer, Karen; Lu, Sijie; Molldrem, Jeffrey J; Glish, Gary L; Armistead, Paul M; Alatrash, Gheath

CD13-positive bone marrow-derived myeloid cells promote angiogenesis, tumor growth, and metastasis

CD13阳性骨髓来源的髓系细胞促进血管生成、肿瘤生长和转移。

Dondossola, Eleonora; Rangel, Roberto; Guzman-Rojas, Liliana; Barbu, Elena M; Hosoya, Hitomi; St John, Lisa S; Molldrem, Jeffrey J; Corti, Angelo; Sidman, Richard L; Arap, Wadih; Pasqualini, Renata