日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dominant α-tubulin mutations rescue tauopathy neurodegenerative phenotypes in C. elegans

显性α-微管蛋白突变可挽救秀丽隐杆线虫的tau蛋白病神经退行性表型

Benbow, Sarah J; Saxton, Aleen D; Baum, Misa; Uhrich, Rikki L; Stair, Jade G; Keene, Kelly; Dahleen, Chloe; Wordeman, Linda; Liachko, Nicole F; Kow, Rebecca L; Kraemer, Brian C

Expression of polyglutamine repeats at the pathogenic threshold modestly enhances tau neurotoxicity and protein accumulation in C. elegans.

在致病阈值下,多聚谷氨酰胺重复序列的表达会适度增强秀丽隐杆线虫的 tau 神经毒性和蛋白质积累

Hincks Joshua C, Stair Jade G, Liachko Nicole F

Transcriptomic evaluation of tau and TDP-43 synergism shows tauopathy predominance and reveals potential modulating targets

转录组学评估显示tau蛋白和TDP-43蛋白的协同作用以tau蛋白病变为主,并揭示了潜在的调控靶点。

Jadhav, Vaishnavi S; Stair, Jade G; Eck, Randall J; Smukowski, Samuel N; Currey, Heather N; Toscano, Laura Garcia; Hincks, Joshua C; Latimer, Caitlin S; Valdmanis, Paul N; Kraemer, Brian C; Liachko, Nicole F

Simple models to understand complex disease: 10 years of progress from Caenorhabditis elegans models of amyotrophic lateral sclerosis and frontotemporal lobar degeneration

利用简单模型理解复杂疾病:秀丽隐杆线虫肌萎缩侧索硬化症和额颞叶变性模型十年来的进展

Eck, Randall J; Stair, Jade G; Kraemer, Brian C; Liachko, Nicole F