日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Parkinson's-Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosa.

帕金森病相关的 LRRK2 和 GBA1 突变调节外周对铜绿假单胞菌的免疫反应。

Mark Julian R, Staley Hannah A, Titus Ann M, Agin-Liebes Julian, Garrido Alicia, Hughes Laura, Dzamko Nicolas, Wallings Rebecca L, Tansey Malú Gámez

ASO-mediated knock-down of GPNMB in mutant-GRN and in Grn-deficient peripheral myeloid cells disrupts lysosomal function and immune responses.

在突变型 GRN 和 Grn 缺陷型外周髓系细胞中,ASO 介导的 GPNMB 敲低会破坏溶酶体功能和免疫反应

Wallings Rebecca L, Gillett Drew A, Staley Hannah A, Mahn Savanna, Mark Julian, Neighbarger Noelle, Kordasiewicz Holly, Hirst Warren D, Tansey Malú Gámez

Peripheral immune cell response to stimulation stratifies Parkinson's disease progression from prodromal to clinical stages.

外周免疫细胞对刺激的反应可将帕金森病的进展从前驱期到临床期进行分层

Mark Julian R, Titus Ann M, Staley Hannah A, Alvarez Stephan, Mahn Savanna, McFarland Nikolaus R, Wallings Rebecca L, Tansey Malú Gámez

The R1441C-Lrrk2 mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner in mice

R1441C-Lrrk2突变以年龄和性别依赖的方式诱导小鼠髓系免疫细胞耗竭。

Wallings, Rebecca L; McFarland, Karen; Staley, Hannah A; Neighbarger, Noelle; Schaake, Susen; Brüggemann, Norbert; Zittel, Simone; Usnich, Tatiana; Klein, Christine; Sammler, Esther M; Tansey, Malú Gámez

RGS10 Attenuates Systemic Immune Dysregulation Induced by Chronic Inflammatory Stress.

RGS10 可减轻慢性炎症应激引起的全身免疫失调

Jernigan Janna E, Staley Hannah A, Baty Zachary, Bolen MacKenzie L, Gomes Beatriz Nuñes, Holt Jenny, Cole Cassandra L, Neighbarger Noelle K, Dheeravath Kruthika, Merchak Andrea R, Menees Kelly B, Coombes Stephen A, Tansey Malú Gámez