Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer
聚合酶θ抑制可激活cGAS-STING通路并与BRCA缺陷癌症模型中的免疫检查点阻断协同作用
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-023-37096-6
Jeffrey Patterson-Fortin, Heta Jadhav, Constantia Pantelidou, Tin Phan, Carter Grochala, Anita K Mehta, Jennifer L Guerriero, Gerburg M Wulf, Brian M Wolpin, Ben Z Stanger, Andrew J Aguirre, James M Cleary, Alan D D'Andrea, Geoffrey I Shapiro
