日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

The hypothalamic RFamide, QRFP, increases feeding and locomotor activity: The role of Gpr103 and orexin receptors

下丘脑 RFamide QRFP 增加摄食和运动活动：Gpr103 和食欲素受体的作用

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0275604
Chris Cook, Nicolas Nunn, Amy A Worth, David A Bechtold, Todd Suter, Susan Gackeheimer, Lisa Foltz, Paul J Emmerson, Michael A Statnick, Simon M Luckman
信号转导
ELISA
WB
Donkey
IgG
发表日期：2022
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The current state of GPCR-based drug discovery to treat metabolic disease

目前基于GPCR的药物研发在治疗代谢疾病方面的现状

期刊:British Journal of Pharmacology
影响因子:7.7
doi:10.1111/bph.14157
Sloop, Kyle W; Emmerson, Paul J; Statnick, Michael A; Willard, Francis S
GPCR/Calcium/cAMP
代谢
发表日期：2018
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Genetic Deletion of the Nociceptin/Orphanin FQ Receptor in the Rat Confers Resilience to the Development of Drug Addiction

大鼠诺西普汀/孤啡肽FQ受体基因缺失可增强其对药物成瘾的抵抗力

期刊:Neuropsychopharmacology
影响因子:7.1
doi:10.1038/npp.2016.171
Kallupi, Marsida; Scuppa, Giulia; de Guglielmo, Giordano; Calò, Girolamo; Weiss, Friedbert; Statnick, Michael A; Rorick-Kehn, Linda M; Ciccocioppo, Roberto
信号转导
Rat
发表日期：2017
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A Selective Nociceptin Receptor Antagonist to Treat Depression: Evidence from Preclinical and Clinical Studies

一种选择性伤害感受素受体拮抗剂治疗抑郁症：来自临床前和临床研究的证据

期刊:Neuropsychopharmacology
影响因子:7.1
doi:10.1038/npp.2015.348
Post, Anke; Smart, Trevor S; Krikke-Workel, Judith; Dawson, Gerard R; Harmer, Catherine J; Browning, Michael; Jackson, Kimberley; Kakar, Rishi; Mohs, Richard; Statnick, Michael; Wafford, Keith; McCarthy, Andrew; Barth, Vanessa; Witkin, Jeffrey M
信号转导
抑郁症
神经科学
发表日期：2016
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A Novel, Orally Bioavailable Nociceptin Receptor Antagonist, LY2940094, Reduces Ethanol Self-Administration and Ethanol Seeking in Animal Models

一种新型的、口服生物利用度高的伤害感受素受体拮抗剂LY2940094可降低动物模型中的乙醇自我给药和乙醇渴求行为。

期刊:Alcoholism-Clinical and Experimental Research
影响因子:2.7
doi:10.1111/acer.13052
Rorick-Kehn, Linda M; Ciccocioppo, Roberto; Wong, Conrad J; Witkin, Jeffrey M; Martinez-Grau, Maria A; Stopponi, Serena; Adams, Benjamin L; Katner, Jason S; Perry, Kenneth W; Toledo, Miguel A; Diaz, Nuria; Lafuente, Celia; Jiménez, Alma; Benito, Ana; Pedregal, Concepción; Weiss, Friedbert; Statnick, Michael A
信号转导
发表日期：2016
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Preclinical findings predicting efficacy and side-effect profile of LY2940094, an antagonist of nociceptin receptors

预测LY2940094（一种伤害感受素受体拮抗剂）疗效和副作用的临床前研究结果

期刊:Pharmacology Research & Perspectives
影响因子:2.3
doi:10.1002/prp2.275
Witkin, Jeffrey M; Rorick-Kehn, Linda M; Benvenga, Mark J; Adams, Benjamin L; Gleason, Scott D; Knitowski, Karen M; Li, Xia; Chaney, Steven; Falcone, Julie F; Smith, Janice W; Foss, Julie; Lloyd, Kirsti; Catlow, John T; McKinzie, David L; Svensson, Kjell A; Barth, Vanessa N; Toledo, Miguel A; Diaz, Nuria; Lafuente, Celia; Jiménez, Alma; Benito, Alfonso; Pedregal, Conception; Martínez-Grau, Maria A; Post, Anke; Ansonoff, Michael A; Pintar, John E; Statnick, Michael A
信号转导
发表日期：2016
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The thermogenic effect of leptin is dependent on a distinct population of prolactin-releasing peptide neurons in the dorsomedial hypothalamus

瘦素的产热作用依赖于下丘脑背内侧的催乳素释放肽神经元群体

期刊:Cell Metabolism
影响因子:27.7
doi:10.1016/j.cmet.2014.07.022
Garron T Dodd, Amy A Worth, Nicolas Nunn, Aaron K Korpal, David A Bechtold, Margaret B Allison, Martin G Myers Jr, Michael A Statnick, Simon M Luckman
神经
发表日期：2014
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The biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence

伤害感受素/孤啡肽FQ (N/OFQ) 的生物学特性与肥胖、压力、焦虑、情绪和药物依赖有关

期刊:Pharmacology & Therapeutics
影响因子:12.5
doi:10.1016/j.pharmthera.2013.10.011
Witkin, Jeffrey M; Statnick, Michael A; Rorick-Kehn, Linda M; Pintar, John E; Ansonoff, Michael; Chen, Yanyun; Tucker, R Craig; Ciccocioppo, Roberto
肥胖
代谢
发表日期：2014
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Mice lacking δ-opioid receptors resist the development of diet-induced obesity

缺乏δ-阿片受体的小鼠能够抵抗饮食诱导的肥胖症的发生。

期刊:FASEB Journal
影响因子:4.2
doi:10.1096/fj.12-208041
Czyzyk, Traci A; Romero-Picó, Amparo; Pintar, John; McKinzie, Jaime H; Tschöp, Matthias H; Statnick, Michael A; Nogueiras, Ruben
信号转导
肥胖
代谢
发表日期：2012
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Synthesis and evaluation of radioligands for imaging brain nociceptin/orphanin FQ peptide (NOP) receptors with positron emission tomography

利用正电子发射断层扫描技术合成和评价用于脑内伤害感受素/孤啡肽FQ肽（NOP）受体成像的放射性配体

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm101487v
Pike, Victor W; Rash, Karen S; Chen, Zhaogen; Pedregal, Concepción; Statnick, Michael A; Kimura, Yasuyuki; Hong, Jinsoo; Zoghbi, Sami S; Fujita, Masahiro; Toledo, Miguel A; Diaz, Nuria; Gackenheimer, Susan L; Tauscher, Johannes T; Barth, Vanessa N; Innis, Robert B
信号转导
神经科学
发表日期：2011
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