日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Emerging novel methodologies to understand and strategically target long-lived plasma cells in vaccine design to induce durable immunity

新兴方法旨在了解并有策略地靶向疫苗设计中的长寿命浆细胞,以诱导持久免疫力。

Cusimano, Gina; Staupe, Ryan P; Sullivan, Nicole L

Development of High-Titer Antidrug Antibodies in a Phase 1b/2a Infant Clesrovimab Trial Are Associated With RSV Exposure Beyond Day 150

在一项针对婴儿的 Clesrovimab 1b/2a 期试验中,高滴度抗药抗体的产生与出生后 150 天以上的 RSV 暴露相关。

Thambi, Nithya; Phuah, Jia Yao; Staupe, Ryan P; Tobias, Lori M; Cao, Yu; McKelvey, Troy; Railkar, Radha A; Aliprantis, Antonios O; Arriola, Carmen Sofia; Maas, Brian M; Vora, Kalpit A

Immunogenicity of RSV Fusion Protein Adsorbed to Non-Pathogenic Bacillus subtilis Spores: Implications for Mucosal Vaccine Delivery in Nonclinical Animal Models

吸附于非致病性枯草芽孢杆菌孢子的呼吸道合胞病毒融合蛋白的免疫原性:对非临床动物模型中粘膜疫苗递送的启示

Xiao, Jianying; Wang, Hao; Callahan, Cheryl; O'Donnell, Gregory; Rodriguez, Silveria; Staupe, Ryan P; Balibar, Carl J; Citron, Michael P

Anti-Idiotypic Antibody as a Booster Vaccine Against Respiratory Syncytial Virus

抗独特型抗体作为呼吸道合胞病毒加强疫苗

Mukhopadhyay, Shreya; Manolaridis, Ioannis; Warren, Christopher; Tang, Aimin; O'Donnell, Gregory; Luo, Bin; Staupe, Ryan P; Vora, Kalpit A; Chen, Zhifeng

In vitro modeling of CD8(+) T cell exhaustion enables CRISPR screening to reveal a role for BHLHE40

体外模拟 CD8(+) T 细胞耗竭,使得 CRISPR 筛选能够揭示 BHLHE40 的作用。

Wu, Jennifer E; Manne, Sasikanth; Ngiow, Shin Foong; Baxter, Amy E; Huang, Hua; Freilich, Elizabeth; Clark, Megan L; Lee, Joanna H; Chen, Zeyu; Khan, Omar; Staupe, Ryan P; Huang, Yinghui J; Shi, Junwei; Giles, Josephine R; Wherry, E John

Systematic analysis of mistletoe prescriptions in clinical studies

对临床研究中槲寄生处方进行系统分析

Staupe, Henrike; Buentzel, Judith; Keinki, Christian; Buentzel, Jens; Huebner, Jutta

In Vitro Modeling of CD8 T Cell Exhaustion Enables CRISPR Screening to Reveal a Role for BHLHE40

CD8 T 细胞衰竭体外建模使 CRISPR 筛选能够揭示 BHLHE40 的作用

Jennifer E Wu, Sasikanth Manne, Shin Foong Ngiow, Amy E Baxter, Hua Huang, Elizabeth Freilich, Megan L Clark, Joanna H Lee, Zeyu Chen, Omar Khan, Ryan P Staupe, Yinghui J Huang, Junwei Shi, Josephine R Giles, E John Wherry

PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine

PD-1 靶向免疫疗法可改变季节性流感疫苗的 Tfh 和体液免疫反应

Ramin Sedaghat Herati #, David A Knorr #, Laura A Vella, Luisa Victoria Silva, Lakshmi Chilukuri, Sokratis A Apostolidis, Alexander C Huang, Alexander Muselman, Sasikanth Manne, Oliva Kuthuru, Ryan P Staupe, Sharon A Adamski, Senthil Kannan, Raj K Kurupati, Hildegund C J Ertl, Jeffrey L Wong, Stylia

Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics

时间单细胞转录组学和表观遗传学揭示效应、记忆和耗竭 CD8+ T 细胞中共享和不同的生物回路

Josephine R Giles, Shin Foong Ngiow, Sasikanth Manne, Amy E Baxter, Omar Khan, Ping Wang, Ryan Staupe, Mohamed S Abdel-Hakeem, Hua Huang, Divij Mathew, Mark M Painter, Jennifer E Wu, Yinghui Jane Huang, Rishi R Goel, Patrick K Yan, Giorgos C Karakousis, Xiaowei Xu, Tara C Mitchell, Alexander C Huang

Single cell multi-omic reference atlases of non-human primate immune tissues reveals CD102 as a biomarker for long-lived plasma cells

非人类灵长类动物免疫组织的单细胞多组学参考图谱显示 CD102 是长寿浆细胞的生物标志物

Ryan P Staupe, Kenneth E Lodge, Nithya Thambi, David Toole, Alex M Tamburino, Dan Chang, Bonnie J Howell, Daria J Hazuda, Kalpit A Vora, Nicole L Sullivan0