日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Chimeric CD3ζ chains containing CD28 signalling motifs enhance antigen-specific IL-2 production and expansion of human TCR-engineered T cells in vitro

含有CD28信号基序的嵌合CD3ζ链可增强抗原特异性IL-2的产生,并促进人TCR工程化T细胞在体外的扩增。

Burgess, Samuel J; Stauss, Hans J; Morris, Emma C

Exploiting TCR Repertoire Analysis to Select Therapeutic TCRs for Cancer Immunotherapy

利用TCR库分析筛选用于癌症免疫治疗的治疗性TCR

Demaël, Ursule M; Rirkkrai, Thunchanok; Okus, Fatma Zehra; Tiffeau-Mayer, Andreas; Stauss, Hans J

Targeted Therapy of Multiple Sclerosis: A Case for Antigen-Specific Tregs

多发性硬化症的靶向治疗:抗原特异性调节性T细胞的案例

Zhong, Yiya; Stauss, Hans J

Synthetic Cell-Based Immunotherapies for Neurologic Diseases

用于治疗神经系统疾病的合成细胞免疫疗法

von Baumgarten, Louisa; Stauss, Hans J; Lünemann, Jan D

Modifications outside CDR1, 2 and 3 of the TCR variable β domain increase TCR expression and antigen-specific function

TCR可变β结构域CDR1、2和3以外的修饰可增加TCR表达和抗原特异性功能。

Degirmencay, Abdullah; Thomas, Sharyn; Mohammed, Fiyaz; Willcox, Benjamin E; Stauss, Hans J

Enhancing the expression and function of an EBV-TCR on engineered T cells by combining Sc-TCR design with CRISPR editing to prevent mispairing

通过将Sc-TCR设计与CRISPR编辑相结合,增强工程化T细胞上EBV-TCR的表达和功能,以防止错配。

Xue, Shao-An; Chen, Yuan; Voss, Ralf-Holger; Kisan, Virad; Wang, Bo; Chen, Ke-Ke; He, Feng-Qin; Cheng, Xiao-Xia; Scolamiero, Laura; Holler, Angelika; Gao, Liquan; Morris, Emma; Stauss, Hans J

Engineering CD4+ T Cells to Enhance Cancer Immunity

基因工程改造CD4+ T细胞以增强癌症免疫力

Sillito, Francesca; Holler, Angelika; Stauss, Hans J

Turn to TCRs when CARs fail

当CAR失效时,转而使用TCR。

Stauss, Hans J

Expression of a dominant T-cell receptor can reduce toxicity and enhance tumor protection of allogeneic T-cell therapy

优势T细胞受体的表达可以降低同种异体T细胞疗法的毒性并增强其对肿瘤的保护作用。

Holler, Angelika; Zech, Mathias; Ghorashian, Sara; Pike, Rebecca; Hotblack, Alastair; Veliça, Pedro; Xue, Shao-An; Chakraverty, Ronjon; Morris, Emma C; Stauss, Hans J

PD1-Expressing T Cell Subsets Modify the Rejection Risk in Renal Transplant Patients

表达PD1的T细胞亚群会影响肾移植患者的排斥风险

Pike, Rebecca; Thomas, Niclas; Workman, Sarita; Ambrose, Lyn; Guzman, David; Sivakumaran, Shivajanani; Johnson, Margaret; Thorburn, Douglas; Harber, Mark; Chain, Benny; Stauss, Hans J