日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

De novo cyclic peptides allow visualisation of the monomeric and functional amyloid conformations of the kinase RIPK3.

从头合成的环状肽能够可视化激酶 RIPK3 的单体和功能性淀粉样蛋白构象。

Buchanan Jessica A, Lavidis Olivia, Shields Nicholas, Harrison Katriona, Nguyen Huy T, Payne Richard J, Passioura Toby, Steain Megan, Sunde Margaret

The Batalogue: an overview of betacoronaviruses with future pandemic potential

战斗日志:具有未来大流行潜力的β冠状病毒概述

Baird, Sarah; Holmes, Edward C; Ashley, Caroline L; Triccas, James A; Steain, Megan

An LNP-mRNA vaccine modulates innate cell trafficking and promotes polyfunctional Th1 CD4+ T cell responses to enhance BCG-induced protective immunity against Mycobacterium tuberculosis

LNP-mRNA 疫苗调节先天细胞运输并促进多功能 Th1 CD4+ T 细胞反应,以增强 BCG 诱导的针对结核分枝杆菌的保护性免疫

Hannah Lukeman, Hareth Al-Wassiti, Stewart A Fabb, Leonard Lim, Trixie Wang, Warwick J Britton, Megan Steain, Colin W Pouton, James A Triccas, Claudio Counoupas

An adjuvanted chimeric spike antigen boosts lung-resident memory T-cells and induces pan-sarbecovirus protective immunity

一种佐剂化的嵌合刺突抗原可增强肺部驻留记忆T细胞,并诱导泛沙贝病毒保护性免疫。

Counoupas, Claudio; Chan, Elizabeth; Pino, Paco; Armitano, Joshua; Johansen, Matt D; Smith, Lachlan J; Ashley, Caroline L; Estapé, Eva; Troyon, Jean; Alca, Sibel; Miemczyk, Stefan; Hansbro, Nicole G; Scandurra, Gabriella; Britton, Warwick J; Courant, Thomas; Dubois, Patrice M; Collin, Nicolas; Mohan, V Krishna; Hansbro, Philip M; Wurm, Maria J; Wurm, Florian M; Steain, Megan; Triccas, James A

Upper respiratory tract immunization with Pam(2)Cys-adjuvanted spike protein vaccine achieves sterilizing protection against SARS-CoV-2.

使用 Pam(2)Cys 佐剂刺突蛋白疫苗进行上呼吸道免疫,可实现对 SARS-CoV-2 的完全保护。

Stewart Erica L, Stockdale Skye, Johansen Matt D, Smith Lachlan, Alca Sibel, Maxwell Joshua W C, Nguyen Duc H, Miemczyk Stefan, Zhao Guanshu, Turville Stuart, Triccas James A, Steain Megan, Byrne Scott N, Hansbro Philip M, Payne Richard J, Britton Warwick J, Ashhurst Anneliese S

An RGD motif on SARS-CoV-2 Spike induces TGF-β signaling and downregulates interferon

SARS-CoV-2 刺突蛋白上的 RGD 基序可诱导 TGF-β 信号通路并下调干扰素。

Gracie, Nicholas P; Aggarwal, Anupriya; Luo, Rachel; Spicer, Mitchell; Idrees, Sobia; Ashley, Caroline L; Alca, Sibel; Ison, Timothy; Steain, Megan C; Patel, Karishma; Siddiquee, Rezwan; Low, Jason K K; Mackay, Joel P; Denes, Christopher E; Neely, G Gregory; Faiz, Alen; Turville, Stuart G; Newsome, Timothy P

Dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) is a cellular receptor for delta inulin adjuvant

树突状细胞特异性细胞间粘附分子-3-抓取非整合素(DC-SIGN)是δ-菊粉佐剂的细胞受体

Stewart, Erica L; Counoupas, Claudio; Steain, Megan; Ashley, Caroline; Alca, Sibel; Hartley-Tassell, Lauren; von Itzstein, Mark; Britton, Warwick J; Petrovsky, Nikolai; Triccas, James A

Late-stage MC38 tumours recapitulate features of human colorectal cancer - implications for appropriate timepoint selection in preclinical studies

晚期 MC38 肿瘤重现人类结直肠癌的特征 - 对临床前研究中适当时间点选择的意义

Nicholas J Shields, Estelle M Peyroux, Angela L Ferguson, Megan Steain, Silke Neumann, Sarah L Young

Varicella Zoster Virus Impairs Expression of the Nonclassical Major Histocompatibility Complex Class I-Related Gene Protein (MR1)

水痘带状疱疹病毒损害非经典主要组织相容性复合体 I 类相关基因蛋白 (MR1) 的表达

Shivam K Purohit, Carolyn Samer, Hamish E G McWilliam, Renee Traves, Megan Steain, Brian P McSharry, Paul R Kinchington, David C Tscharke, Jose A Villadangos, Jamie Rossjohn, Allison Abendroth, Barry Slobedman

A unique cytotoxic CD4(+) T cell-signature defines critical COVID-19

一种独特的细胞毒性 CD4(+) T 细胞特征定义了危重 COVID-19

Baird, Sarah; Ashley, Caroline L; Marsh-Wakefield, Felix; Alca, Sibel; Ashhurst, Thomas M; Ferguson, Angela L; Lukeman, Hannah; Counoupas, Claudio; Post, Jeffrey J; Konecny, Pamela; Bartlett, Adam; Martinello, Marianne; Bull, Rowena A; Lloyd, Andrew; Grey, Alice; Hutchings, Owen; Palendira, Umaimainthan; Britton, Warwick J; Steain, Megan; Triccas, James A