日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting Pediatric Glioblastomas by Combining OLIG2 Inhibitor CT-179 with Fractionated Radiation in a Panel of Patient-Derived Orthotopic Xenograft Mouse Models

在患者来源的原位异种移植小鼠模型中,将OLIG2抑制剂CT-179与分次放射治疗相结合,靶向治疗儿童胶质母细胞瘤

Lindsay, Holly; Du, Yuchen; Qi, Lin; Zhang, Huiyuan; Zhao, Sibo; Braun, Frank K; Kogiso, Mari; Stephan, Clifford; Alton, Gordon; Stein, Gregory; Beaton, Graham; Kesari, Santosh; Neuhauser, Steve; Stearns, Tim; Chuang, Jeff; Jocoy, Emily L; Bult, Carol J; Teicher, Beverly; Smith, Malcolm A; Li, Xiao-Nan

Molecular architecture of the ciliary base in mammalian multiciliated cells

哺乳动物多纤毛细胞纤毛基部的分子结构

McCafferty, Caitlyn L; Brunet, Marine; van den Hoek, Hugo; Buss, Garrison; Mercey, Olivier; Van der Stappen, Philippe; Ritz, Danilo; Müller, Adrian; Righetto, Ricardo; Guichard, Paul; Hamel, Virginie; Stearns, Tim; Engel, Benjamin D

A delta-tubulin/epsilon-tubulin/Ted protein complex is required for centriole architecture.

中心粒结构需要δ-微管蛋白/ε-微管蛋白/Ted蛋白复合物

Pudlowski Rachel, Xu Lingyi, Milenkovic Ljiljana, Kumar Chandan, Hemsworth Katherine, Aqrabawi Zayd, Stearns Tim, Wang Jennifer T

Centriole biogenesis is seeded by CEP152-CEP63-PCNT aggregates propagating outside the centriole through the Alström syndrome protein ALMS1

中心粒的生物发生是由CEP152-CEP63-PCNT聚集体通过Alström综合征蛋白ALMS1在中心粒外传播而引发的。

Ozaki, Kanako; Chang, Ting-Jui Ben; Yang, Wen-Qing; Shulman, Avital; Izquierdo, Denisse; Jane, Wann-Neng; Wang, Won-Jing; Stearns, Tim; Luders, Jens; Yang, T Tony; Tsou, Meng-Fu Bryan

Dynamic remodeling of centrioles and the microtubule cytoskeleton in the lifecycle of chytrid fungi

壶菌生命周期中中心粒和微管细胞骨架的动态重塑

Long, Alexandra F; Vasudevan, Krishnakumar; Swafford, Andrew J M; Venard, Claire M; Stajich, Jason E; Fritz-Laylin, Lillian K; Feldman, Jessica L; Stearns, Tim

The Luminal Ring Protein C2CD3 Acts as a Radial In-to-Out Organizer of the Distal Centriole and Appendages.

腔环蛋白 C2CD3 起到远端中心粒及其附属物的径向由内向外组织者的作用

Bertiaux Eloïse, Louvel Vincent, McCafferty Caitlyn L, van den Hoek Hugo, Batman Umut, Mukherjee Souradip, Bournonville Lorène, Mercey Olivier, Mean Isabelle, Müller Adrian, Van der Stappen Philippe, Buss Garrison, Daraspe Jean, Genoud Christel, Stearns Tim, Engel Benjamin D, Hamel Virginie, Guichard Paul

Mouse Phenome Database: towards a more FAIR-compliant and TRUST-worthy data repository and tool suite for phenotypes and genotypes

小鼠表型组数据库:构建更符合 FAIR 原则且更值得信赖的表型和基因型数据存储库和工具套件

Bogue, Molly A; Ball, Robyn L; Philip, Vivek M; Walton, David O; Dunn, Matthew H; Kolishovski, Georgi; Lamoureux, Anna; Gerring, Matthew; Liang, Hongping; Emerson, Jake; Stearns, Tim; He, Hao; Mukherjee, Gaurab; Bluis, John; Desai, Sejal; Sundberg, Beth; Kadakkuzha, Beena; Kunde-Ramamoorthy, Govindarajan; Chesler, Elissa J

In vivo activity of the dual SYK/FLT3 inhibitor TAK-659 against pediatric acute lymphoblastic leukemia xenografts

双重SYK/FLT3抑制剂TAK-659对儿童急性淋巴细胞白血病异种移植瘤的体内活性

Hughes, Keira; Evans, Kathryn; Earley, Eric J; Smith, Christopher M; Erickson, Stephen W; Stearns, Tim; Philip, Vivek M; Neuhauser, Steven B; Chuang, Jeffrey H; Jocoy, Emily L; Bult, Carol J; Teicher, Beverly A; Smith, Malcolm A; Lock, Richard B

MAP9/MAPH-9 supports axonemal microtubule doublets and modulates motor movement

MAP9/MAPH-9 支持轴丝微管双联体并调节运动神经元的运动

Tran, Michael V; Ferguson, James W; Cote, Lauren E; Khuntsariya, Daria; Fetter, Richard D; Wang, Jennifer T; Wellard, Stephen R; Sallee, Maria D; Genova, Mariya; Eskinazi, Sani; Magiera, Maria M; Janke, Carsten; Stearns, Tim; Lansky, Zdenek; Shen, Kang; Magescas, Jérémy; Feldman, Jessica L

Investigate the origins of COVID-19

调查新冠病毒的起源

Bloom, Jesse D; Chan, Yujia Alina; Baric, Ralph S; Bjorkman, Pamela J; Cobey, Sarah; Deverman, Benjamin E; Fisman, David N; Gupta, Ravindra; Iwasaki, Akiko; Lipsitch, Marc; Medzhitov, Ruslan; Neher, Richard A; Nielsen, Rasmus; Patterson, Nick; Stearns, Tim; van Nimwegen, Erik; Worobey, Michael; Relman, David A