日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lessons learned from 20 years of preclinical testing in pediatric cancers

从20年的儿科癌症临床前试验中汲取的经验教训

Smith, Malcolm A; Houghton, Peter J; Lock, Richard B; Maris, John M; Gorlick, Richard; Kurmasheva, Raushan T; Li, Xiao-Nan; Teicher, Beverly A; Chuang, Jeffrey H; Dela Cruz, Filemon S; Dyer, Michael A; Kung, Andrew L; Lloyd, Michael W; Mossé, Yael P; Stearns, Timothy M; Stewart, Elizabeth A; Bult, Carol J; Erickson, Stephen W

Transcriptional and functional consequences of Oncostatin M signaling on young Dnmt3a-mutant hematopoietic stem cells

Oncostatin M 信号对年轻的 Dnmt3a 突变造血干细胞的转录和功能影响

Schwartz, Logan S; Young, Kira A; Stearns, Timothy M; Boyer, Nathan; Mujica, Kristina D; Trowbridge, Jennifer J

Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response in mice and humans.

绘制小鼠和人类肿瘤免疫微环境的遗传图谱,以建立有利于抗PD-1反应的肿瘤免疫微环境

Skelly Daniel A, Graham John P, Cheng Mingshan, Furuta Mayuko, Walter Andrew, Stoklasek Thomas A, Yang Hongyuan, Stearns Timothy M, Poirion Olivier, Zhang Ji-Gang, Grassmann Jessica D S, Luo Diane, Flynn William F, Courtois Elise T, Chang Chih-Hao, Serreze David V, Menghi Francesca, Reinholdt Laura G, Liu Edison T

Matrix Metalloproteinase 7 Expression and Apical Epithelial Defects in Atp8b1 Mutant Mouse Model of Pulmonary Fibrosis

基质金属蛋白酶7表达和肺纤维化Atp8b1突变小鼠模型中的顶端上皮缺陷

Westermann-Clark, Emma; Soundararajan, Ramani; Fukumoto, Jutaro; Patil, Sahebgowda Sidramagowda; Stearns, Timothy M; Saji, Smita; Czachor, Alexander; Hernandez-Cuervo, Helena; Breitzig, Mason; Krishnamurthy, Sudarshan; Lockey, Richard F; Kolliputi, Narasaiah

Glycine supplementation extends lifespan of male and female mice.

补充甘氨酸可延长雄性和雌性小鼠的寿命

Miller Richard A, Harrison David E, Astle C Michael, Bogue Molly A, Brind Joel, Fernandez Elizabeth, Flurkey Kevin, Javors Martin, Ladiges Warren, Leeuwenburgh Christiaan, Macchiarini Francesca, Nelson James, Ryazanov Alexey G, Snyder Jessica, Stearns Timothy M, Vaughan Douglas E, Strong Randy

Factors that influence response classifications in chemotherapy treated patient-derived xenografts (PDX)

影响化疗治疗的患者来源异种移植(PDX)疗效分级的因素

Malcolm, Joan E; Stearns, Timothy M; Airhart, Susan D; Graber, Joel H; Bult, Carol J

Modeling Genetic Susceptibility to Disease

疾病遗传易感性建模

Li, Qiaoli; Philip, Vivek M; Stearns, Timothy M; Bubier, Jason A; King, Benjamin L; Low, Benjamin E; Wiles, Michael V; Saeidian, Amir Hossein; Sundberg, Beth A; Uitto, Jouni; Sundberg, John P; Veith, AC; Chu, C; Moorthy, B

Early induction of NRF2 antioxidant pathway by RHBDF2 mediates rapid cutaneous wound healing

RHBDF2早期诱导NRF2抗氧化通路可促进皮肤伤口快速愈合。

Hosur, Vishnu; Burzenski, Lisa M; Stearns, Timothy M; Farley, Michelle L; Sundberg, John P; Wiles, Michael V; Shultz, Leonard D

Loss of FAS/FASL signalling does not reduce apoptosis in Sharpin null mice

FAS/FASL信号通路缺失并不能减少Sharpin基因敲除小鼠的细胞凋亡。

Potter, Christopher S; Silva, Kathleen A; Kennedy, Victoria E; Stearns, Timothy M; HogenEsch, Harm; Sundberg, John P

Detection of canonical A-to-G editing events at 3' UTRs and microRNA target sites in human lungs using next-generation sequencing

利用新一代测序技术检测人肺组织中3'非翻译区和microRNA靶位点的典型A-to-G编辑事件

Soundararajan, Ramani; Stearns, Timothy M; Griswold, Anthony L; Mehta, Arpit; Czachor, Alexander; Fukumoto, Jutaro; Lockey, Richard F; King, Benjamin L; Kolliputi, Narasaiah