日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intrastriatal injection of alpha-synuclein preformed fibrils to rats results in L-DOPA reversible sensorimotor impairments and alterations in non-motor function.

向大鼠纹状体内注射α-突触核蛋白预成型原纤维会导致左旋多巴可逆的感觉运动障碍和非运动功能改变

Fleming Sheila M, Scott Sophia, Hamad Edward J, Herman Danielle E, Holden John G, Yan Lily, Linning-Duffy Katrina, Kemp Christopher J, Patterson Joseph R, Miller Kathryn M, Kubik Michael, Kuhn Nathan, Stoll Anna C, Duffy Megan F, Steece-Collier Kathy, Cole-Strauss Allyson, Lipton Jack W, Luk Kelvin C, Sortwell Caryl E

The Impact of Brain-Derived Neurotrophic Factor rs6265 (Val66Met) Polymorphism on Therapeutic Electrical Stimulation for Peripheral Nerve Regeneration: A Preclinical Study of Therapy-Genotype Interactions

脑源性神经营养因子rs6265(Val66Met)多态性对周围神经再生治疗性电刺激的影响:治疗-基因型相互作用的临床前研究

Jordan B Walters ,Maria J Quezada ,Suning He ,Ciara S Haynes ,Kathy Steece-Collier ,Timothy J Collier ,Caryl E Sortwell ,Colin K Franz

Advancing age and the rs6265 BDNF SNP are permissive to graft-induced dyskinesias in parkinsonian rats

年龄增长和 rs6265 BDNF SNP 导致帕金森病大鼠发生移植物诱发的运动障碍

Natosha M Mercado #, Carlye Szarowicz #, Jennifer A Stancati, Caryl E Sortwell, Samuel A Boezwinkle, Timothy J Collier, Margaret E Caulfield, Kathy Steece-Collier

Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils

用预先形成的纤维诱导的大鼠早期突触核蛋白病的转录组分析

Joseph R Patterson ,Joseph Kochmanski ,Anna C Stoll ,Michael Kubik ,Christopher J Kemp ,Megan F Duffy ,Kajene Thompson ,Jacob W Howe ,Allyson Cole-Strauss ,Nathan C Kuhn ,Kathryn M Miller ,Seth Nelson ,Christopher U Onyekpe ,John S Beck ,Scott E Counts ,Alison I Bernstein ,Kathy Steece-Collier ,Kelvin C Luk ,Caryl E Sortwell

Engineered AAV capsid transport mutants overcome transduction deficiencies in the aged CNS

经过基因工程改造的AAV衣壳转运突变体克服了老年中枢神经系统中的转导缺陷。

Ivette M Sandoval ,Christy M Kelley ,Luis Daniel Bernal-Conde ,Kathy Steece-Collier ,David J Marmion ,Marcus Davidsson ,Sean M Crosson ,Sanford L Boye ,Shannon E Boye ,Fredric P Manfredsson

Neuroinflammatory gene expression profiles of reactive glia in the substantia nigra suggest a multidimensional immune response to alpha synuclein inclusions

黑质反应性胶质细胞的神经炎症基因表达谱表明,针对α-突触核蛋白包涵体的免疫反应是多维度的。

Anna C Stoll ,Christopher J Kemp ,Joseph R Patterson ,Jacob W Howe ,Kathy Steece-Collier ,Kelvin C Luk ,Caryl E Sortwell ,Matthew J Benskey

Downregulation of striatal Ca(V)1.3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age

纹状体Ca(V)1.3的下调抑制了老年帕金森病雄性和雌性大鼠左旋多巴诱导的运动障碍的加重。

Caulfield, Margaret E; Vander Werp, Molly J; Stancati, Jennifer A; Collier, Timothy J; Sortwell, Caryl E; Sandoval, Ivette M; Manfredsson, Fredric P; Steece-Collier, Kathy

Quinpirole inhibits levodopa-induced dyskinesias at structural and behavioral levels: Efficacy negated by co-administration of isradipine

喹吡罗在结构和行为层面抑制左旋多巴诱发的运动障碍:与伊拉地平合用会抵消其疗效。

Collier, Timothy J; Begg, Lauren; Stancati, Jennifer A; Mercado, Natosha M; Sellnow, Rhyomi C; Sandoval, Ivette M; Sortwell, Caryl E; Steece-Collier, Kathy

A comparison of machine learning approaches for the quantification of microglial cells in the brain of mice, rats and non-human primates

比较机器学习方法在小鼠、大鼠和非人灵长类动物脑内小胶质细胞定量分析中的应用

Anwer, Danish M; Gubinelli, Francesco; Kurt, Yunus A; Sarauskyte, Livija; Jacobs, Febe; Venuti, Chiara; Sandoval, Ivette M; Yang, Yiyi; Stancati, Jennifer; Mazzocchi, Martina; Brandi, Edoardo; O'Keeffe, Gerard; Steece-Collier, Kathy; Li, Jia-Yi; Deierborg, Tomas; Manfredsson, Fredric P; Davidsson, Marcus; Heuer, Andreas

Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in protein

β2-肾上腺素受体激动剂克伦特罗会导致 α-突触核蛋白 mRNA 暂时减少,但不会导致蛋白质长期减少

Joseph R Patterson, Warren D Hirst, Jacob W Howe, Christopher P Russell, Allyson Cole-Strauss, Christopher J Kemp, Megan F Duffy, Jared Lamp, Andrew Umstead, Michael Kubik, Anna C Stoll, Irving E Vega, Kathy Steece-Collier, Yi Chen, Anne C Campbell, Catherine L Nezich, Kelly E Glajch, Caryl E Sortwe