日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intrastriatal injection of alpha-synuclein preformed fibrils to rats results in L-DOPA reversible sensorimotor impairments and alterations in non-motor function.

向大鼠纹状体内注射α-突触核蛋白预成型原纤维会导致左旋多巴可逆的感觉运动障碍和非运动功能改变

Fleming Sheila M, Scott Sophia, Hamad Edward J, Herman Danielle E, Holden John G, Yan Lily, Linning-Duffy Katrina, Kemp Christopher J, Patterson Joseph R, Miller Kathryn M, Kubik Michael, Kuhn Nathan, Stoll Anna C, Duffy Megan F, Steece-Collier Kathy, Cole-Strauss Allyson, Lipton Jack W, Luk Kelvin C, Sortwell Caryl E

Downregulation of striatal Ca(V)1.3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age

纹状体Ca(V)1.3的下调抑制了老年帕金森病雄性和雌性大鼠左旋多巴诱导的运动障碍的加重。

Caulfield, Margaret E; Vander Werp, Molly J; Stancati, Jennifer A; Collier, Timothy J; Sortwell, Caryl E; Sandoval, Ivette M; Manfredsson, Fredric P; Steece-Collier, Kathy

Quinpirole inhibits levodopa-induced dyskinesias at structural and behavioral levels: Efficacy negated by co-administration of isradipine

喹吡罗在结构和行为层面抑制左旋多巴诱发的运动障碍:与伊拉地平合用会抵消其疗效。

Collier, Timothy J; Begg, Lauren; Stancati, Jennifer A; Mercado, Natosha M; Sellnow, Rhyomi C; Sandoval, Ivette M; Sortwell, Caryl E; Steece-Collier, Kathy

A comparison of machine learning approaches for the quantification of microglial cells in the brain of mice, rats and non-human primates

比较机器学习方法在小鼠、大鼠和非人灵长类动物脑内小胶质细胞定量分析中的应用

Anwer, Danish M; Gubinelli, Francesco; Kurt, Yunus A; Sarauskyte, Livija; Jacobs, Febe; Venuti, Chiara; Sandoval, Ivette M; Yang, Yiyi; Stancati, Jennifer; Mazzocchi, Martina; Brandi, Edoardo; O'Keeffe, Gerard; Steece-Collier, Kathy; Li, Jia-Yi; Deierborg, Tomas; Manfredsson, Fredric P; Davidsson, Marcus; Heuer, Andreas

Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease

在帕金森病大鼠模型中诱导和评估左旋多巴诱发的运动障碍

Caulfield, Margaret E; Stancati, Jennifer A; Steece-Collier, Kathy

Striatal Nurr1, but not FosB expression links a levodopa-induced dyskinesia phenotype to genotype in Fisher 344 vs. Lewis hemiparkinsonian rats

纹状体 Nurr1 表达(而非 FosB 表达)将左旋多巴诱导的运动障碍表型与 Fisher 344 和 Lewis 半侧帕金森病大鼠的基因型联系起来。

Steece-Collier, Kathy; Collier, Timothy J; Lipton, Jack W; Stancati, Jennifer A; Winn, Mary E; Cole-Strauss, Allyson; Sellnow, Rhyomi; Conti, Melissa M; Mercado, Natosha M; Nillni, Eduardo A; Sortwell, Caryl E; Manfredsson, Fredric P; Bishop, Christopher

Cell therapy for Parkinson's disease: Why it doesn't work every time

细胞疗法治疗帕金森病:为什么并非每次都有效

Collier, Timothy J; Sortwell, Caryl E; Mercado, Natosha M; Steece-Collier, Kathy

Is Alpha-Synuclein Loss-of-Function a Contributor to Parkinsonian Pathology? Evidence from Non-human Primates

α-突触核蛋白功能丧失是帕金森病病理的促成因素吗?来自非人灵长类动物的证据

Collier, Timothy J; Redmond, D Eugene Jr; Steece-Collier, Kathy; Lipton, Jack W; Manfredsson, Fredric P

Repairing the Aged Parkinsonian Striatum: Lessons from the Lab and Clinic

修复老年帕金森病纹状体:来自实验室和临床的经验

Mercado, Natosha M; Collier, Timothy J; Freeman, Thomas; Steece-Collier, Kathy

Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration

将预先形成的鼠α-突触核蛋白原纤维注射到大鼠纹状体内,可诱发α-突触核蛋白病理和双侧黑质纹状体变性。

Paumier, Katrina L; Luk, Kelvin C; Manfredsson, Fredric P; Kanaan, Nicholas M; Lipton, Jack W; Collier, Timothy J; Steece-Collier, Kathy; Kemp, Christopher J; Celano, Stephanie; Schulz, Emily; Sandoval, Ivette M; Fleming, Sheila; Dirr, Elliott; Polinski, Nicole K; Trojanowski, John Q; Lee, Virginia M; Sortwell, Caryl E