日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Impact of FcRn antagonism on vaccine-induced protective immune responses against viral challenge in COVID-19 and influenza mouse vaccination models.

FcRn拮抗作用对COVID-19和流感小鼠疫苗接种模型中疫苗诱导的抗病毒攻击的保护性免疫反应的影响

Warang Prajakta, Singh Gagandeep, Moshir Mahan, Binazon Ornella, Laghlali Gabriel, Chang Lauren A, Wouters Heidi, Vanhoenacker Peter, Notebaert Margo, Elhemdaoui Nadia, Augustynková Kateřina, Steeland Sophie, Ulrichts Peter, Baumeister Judith, Schotsaert Michael

Subcutaneous efgartigimod PH20 in generalized myasthenia gravis: A phase 3 randomized noninferiority study (ADAPT-SC) and interim analyses of a long-term open-label extension study (ADAPT-SC+)

皮下注射efgartigimod PH20治疗全身型重症肌无力:一项3期随机非劣效性研究(ADAPT-SC)和一项长期开放标签扩展研究(ADAPT-SC+)的中期分析

Howard, James F Jr; Vu, Tuan; Li, George; Korobko, Denis; Smilowski, Marek; Liu, Li; Gistelinck, Fien; Steeland, Sophie; Noukens, Jan; Van Hoorick, Benjamin; Podhorna, Jana; Borgions, Filip; Li, Yuebing; Utsugisawa, Kimiaki; Wiendl, Heinz; De Bleecker, Jan L; Mantegazza, Renato

Long-term safety, tolerability, and efficacy of efgartigimod (ADAPT+): interim results from a phase 3 open-label extension study in participants with generalized myasthenia gravis

efgartigimod (ADAPT+) 的长期安全性、耐受性和有效性:一项针对全身型重症肌无力患者的 3 期开放标签扩展研究的中期结果

Howard, James F Jr; Bril, Vera; Vu, Tuan; Karam, Chafic; Peric, Stojan; De Bleecker, Jan L; Murai, Hiroyuki; Meisel, Andreas; Beydoun, Said R; Pasnoor, Mamatha; Guglietta, Antonio; Van Hoorick, Benjamin; Steeland, Sophie; T'joen, Caroline; Utsugisawa, Kimiaki; Verschuuren, Jan; Mantegazza, Renato

Choroid plexus tumor necrosis factor receptor 1: A new neuroinflammatory piece of the complex Alzheimer's disease puzzle

脉络丛肿瘤坏死因子受体1:阿尔茨海默病复杂谜题中新的神经炎症环节

Steeland, Sophie; Vandenbroucke, Roosmarijn E

A Study of Cecal Ligation and Puncture-Induced Sepsis in Tissue-Specific Tumor Necrosis Factor Receptor 1-Deficient Mice

组织特异性肿瘤坏死因子受体 1 缺陷小鼠盲肠结扎和穿刺诱发脓毒症的研究

Jolien Vandewalle, Sophie Steeland, Sara Van Ryckeghem, Melanie Eggermont, Elien Van Wonterghem, Roosmarijn E Vandenbroucke, Claude Libert

Counteracting the effects of TNF receptor-1 has therapeutic potential in Alzheimer's disease

抵消 TNF 受体-1 的作用具有治疗阿尔茨海默病的潜力

Sophie Steeland, Nina Gorlé, Charysse Vandendriessche, Sriram Balusu, Marjana Brkic, Caroline Van Cauwenberghe, Griet Van Imschoot, Elien Van Wonterghem, Riet De Rycke, Anneke Kremer, Saskia Lippens, Edward Stopa, Conrad E Johanson, Claude Libert, Roosmarijn E Vandenbroucke

A pilot study on immuno-psychiatry in the 22q11.2 deletion syndrome: A role for Th17 cells in psychosis?

22q11.2缺失综合征免疫精神病学的初步研究:Th17细胞在精神病中的作用?

Vergaelen, Elfi; Schiweck, Carmen; Van Steeland, Kristof; Counotte, Jacqueline; Veling, Wim; Swillen, Ann; Drexhage, Hemmo; Claes, Stephan

A New Venue of TNF Targeting

TNF靶向治疗的新途径

Steeland, Sophie; Libert, Claude; Vandenbroucke, Roosmarijn E

TNFR1 inhibition with a Nanobody protects against EAE development in mice

使用纳米抗体抑制 TNFR1 可防止小鼠 EAE 的发展

Sophie Steeland, Sara Van Ryckeghem, Griet Van Imschoot, Riet De Rycke, Wendy Toussaint, Leen Vanhoutte, Christian Vanhove, Filip De Vos, Roosmarijn E Vandenbroucke, Claude Libert

Development and Validation of a Small Single-domain Antibody That Effectively Inhibits Matrix Metalloproteinase 8

开发和验证一种能有效抑制基质金属蛋白酶8的小型单域抗体

Delphine Demeestere ,Eline Dejonckheere ,Sophie Steeland ,Paco Hulpiau ,Jurgen Haustraete ,Nick Devoogdt ,Rielana Wichert ,Christoph Becker-Pauly ,Elien Van Wonterghem ,Sylviane Dewaele ,Griet Van Imschoot ,Jeroen Aerts ,Lutgarde Arckens ,Yvan Saeys ,Claude Libert ,Roosmarijn E Vandenbroucke