日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanisms of neurodevelopmental toxicity of topiramate

托吡酯神经发育毒性的机制

Steele, John W; Krishnan, Vaishnav; Finnell, Richard H

Excess folic acid intake increases DNA de novo point mutations

过量摄入叶酸会增加DNA新发点突变。

Cao, Xuanye; Xu, Jianfeng; Lin, Ying L; Cabrera, Robert M; Chen, Qiuying; Zhang, Chaofan; Steele, John W; Han, Xiao; Gross, Steven S; Wlodarczyk, Bogdan J; Lupski, James R; Li, Wei; Wang, Hongyan; Finnell, Richard H; Lei, Yunping

Embryonic Hypotaurine Levels Contribute to Strain-Dependent Susceptibility in Mouse Models of Valproate-Induced Neural Tube Defects

胚胎期下牛磺酸水平与丙戊酸诱导神经管缺陷小鼠模型的品系依赖性易感性有关

Steele, John W; Lin, Ying Linda; Chen, Nellie; Wlodarczyk, Bogdan J; Chen, Qiuying; Attarwala, Nabeel; Venkatesalu, Madhu; Cabrera, Robert M; Gross, Steven S; Finnell, Richard H

Unraveling the complex genetics of neural tube defects: From biological models to human genomics and back

揭开神经管缺陷复杂遗传学的面纱:从生物模型到人类基因组学再回到生物模型

Wolujewicz, Paul; Steele, John W; Kaltschmidt, Julia A; Finnell, Richard H; Ross, Margaret Elizabeth

Heritable spina bifida in sheep: A potential model for fetal repair of myelomeningocele

绵羊遗传性脊柱裂:脊髓脊膜膨出胎儿修复的潜在模型

Steele, John W; Bayliss, Sharon; Bayliss, John; Lin, Ying Linda; Wlodarczyk, Bogdan J; Cabrera, Robert M; Asfaw, Yohannes G; Cummings, Thomas J; Finnell, Richard H; George, Timothy M

One-carbon metabolism and folate transporter genes: Do they factor prominently in the genetic etiology of neural tube defects?

一碳代谢和叶酸转运蛋白基因:它们在神经管缺陷的遗传病因学中起重要作用吗?

Steele, John W; Kim, Sung-Eun; Finnell, Richard H

Modeling Niemann Pick type C1 using human embryonic and induced pluripotent stem cells

利用人类胚胎干细胞和诱导多能干细胞构建尼曼-匹克C1型模型

Ordoñez, M Paulina; Steele, John W

Effective anti-Alzheimer Aβ therapy involves depletion of specific Aβ oligomer subtypes

有效的抗阿尔茨海默病Aβ疗法涉及清除特定的Aβ寡聚体亚型。

Knight, Elysse M; Kim, Soong Ho; Kottwitz, Jessica C; Hatami, Asa; Albay, Ricardo; Suzuki, Akinobu; Lublin, Alex; Alberini, Cristina M; Klein, William L; Szabo, Paul; Relkin, Norman R; Ehrlich, Michelle; Glabe, Charles G; Gandy, Sam; Steele, John W

Bringing dead proteins back to life

让死去的蛋白质复活

A Wustman, Brandon; Steele, John W; Sjoberg, Eric R; Stevens, Anthony C

Molecular topology as novel strategy for discovery of drugs with aβ lowering and anti-aggregation dual activities for Alzheimer's disease

分子拓扑结构作为一种新型策略,可用于发现具有降低β-淀粉样蛋白水平和抗聚集双重活性的阿尔茨海默病药物

Wang, Jun; Land, David; Ono, Kenjiro; Galvez, Jorge; Zhao, Wei; Vempati, Prashant; Steele, John W; Cheng, Alice; Yamada, Masahito; Levine, Samara; Mazzola, Paolo; Pasinetti, Giulio M