Steffen Grampp相关文献与解析，生知库 | 链接生命科学的每一步

The renal cancer risk allele at 14q24.2 activates a novel hypoxia-inducible transcription factor-binding enhancer of DPF3 expression

14q24.2 处的肾癌风险等位基因激活了一种新的缺氧诱导转录因子结合增强剂，可增强 DPF3 的表达

doi:10.1016/j.jbc.2022.101699

Johanna Protze, Stephanie Naas, René Krüger, Christine Stöhr, Andre Kraus, Steffen Grampp, Michael Wiesener, Mario Schiffer, Arndt Hartmann, Bernd Wullich, Johannes Schödel

Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)-mediated induction of the long noncoding RNA NICI

缺氧通过缺氧诱导转录因子 (HIF) 介导的长链非编码 RNA NICI 诱导葡萄糖转运蛋白 3 的表达

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1074/jbc.RA119.009827

Victoria Lauer, Steffen Grampp, James Platt, Veronique Lafleur, Olivia Lombardi, Hani Choudhry, Franziska Kranz, Arndt Hartmann, Bernd Wullich, Atsushi Yamamoto, Mathew L Coleman, Peter J Ratcliffe, David R Mole, Johannes Schödel

Inhibition of oxygen-sensing prolyl hydroxylases increases lipid accumulation in human primary tubular epithelial cells without inducing ER stress

抑制氧敏感脯氨酰羟化酶可增加人类原代肾小管上皮细胞中的脂质积累，而不会诱导内质网应激

期刊:Cell and Tissue Research

影响因子:3.2

doi:10.1007/s00441-020-03186-w

Gunnar Schley, Steffen Grampp, Margarete Goppelt-Struebe

Macrophage migration inhibitory factor is regulated by HIF-1α and cAMP and promotes renal cyst cell proliferation in a macrophage-independent manner

巨噬细胞移动抑制因子受 HIF-1α 和 cAMP 调控，以巨噬细胞非依赖的方式促进肾囊肿细胞增殖

期刊:Journal of Molecular Medicine-Jmm

影响因子:

doi:10.1007/s00109-020-01964-1

Wajima Safi, Andre Kraus, Steffen Grampp, Johannes Schödel, Bjoern Buchholz

Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway

多种肾癌易感性多态性调节 HIF 通路

期刊:PLoS Genetics

影响因子:

doi:10.1371/journal.pgen.1006872

Steffen Grampp, Virginia Schmid, Rafik Salama, Victoria Lauer, Franziska Kranz, James L Platt, James Smythies, Hani Choudhry, Margarete Goppelt-Struebe, Peter J Ratcliffe, David R Mole, Johannes Schödel

Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer

8q24.21 肾癌易感基因位点的遗传变异影响 HIF 与 MYC 增强子的结合

期刊:Nature Communications

影响因子:14.7

doi:10.1038/ncomms13183

Steffen Grampp, James L Platt, Victoria Lauer, Rafik Salama, Franziska Kranz, Viviana K Neumann, Sven Wach, Christine Stöhr, Arndt Hartmann, Kai-Uwe Eckardt, Peter J Ratcliffe, David R Mole, Johannes Schödel

P2Y2R is a direct target of HIF-1α and mediates secretion-dependent cyst growth of renal cyst-forming epithelial cells

P2Y2R 是 HIF-1α 的直接靶点，介导肾囊肿形成上皮细胞的分泌依赖性囊肿生长

期刊:Purinergic Signalling

影响因子:3

doi:10.1007/s11302-016-9532-5

Andre Kraus, Steffen Grampp, Margarete Goppelt-Struebe, Rainer Schreiber, Karl Kunzelmann, Dorien J M Peters, Jens Leipziger, Gunnar Schley, Johannes Schödel, Kai-Uwe Eckardt, Bjoern Buchholz

Hypoxia controls expression of kidney-pathogenic MUC1 variants

缺氧控制肾脏致病 MUC1 变体的表达

Hypoxia induces polycystin-1 expression in the renal epithelium

缺氧诱导肾上皮多囊蛋白-1表达

Loss of Polycystin-1 causes cAMP-dependent switch from tubule to cyst formation

多囊蛋白-1的缺失导致cAMP依赖性从小管转变为囊肿形成

The renal cancer risk allele at 14q24.2 activates a novel hypoxia-inducible transcription factor-binding enhancer of DPF3 expression

14q24.2 处的肾癌风险等位基因激活了一种新的缺氧诱导转录因子结合增强剂，可增强 DPF3 的表达

Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)-mediated induction of the long noncoding RNA NICI

缺氧通过缺氧诱导转录因子 (HIF) 介导的长链非编码 RNA NICI 诱导葡萄糖转运蛋白 3 的表达

Inhibition of oxygen-sensing prolyl hydroxylases increases lipid accumulation in human primary tubular epithelial cells without inducing ER stress

抑制氧敏感脯氨酰羟化酶可增加人类原代肾小管上皮细胞中的脂质积累，而不会诱导内质网应激

Macrophage migration inhibitory factor is regulated by HIF-1α and cAMP and promotes renal cyst cell proliferation in a macrophage-independent manner

巨噬细胞移动抑制因子受 HIF-1α 和 cAMP 调控，以巨噬细胞非依赖的方式促进肾囊肿细胞增殖

Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway

多种肾癌易感性多态性调节 HIF 通路

Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer

8q24.21 肾癌易感基因位点的遗传变异影响 HIF 与 MYC 增强子的结合

P2Y2R is a direct target of HIF-1α and mediates secretion-dependent cyst growth of renal cyst-forming epithelial cells

P2Y2R 是 HIF-1α 的直接靶点，介导肾囊肿形成上皮细胞的分泌依赖性囊肿生长