A critical residue in a conserved RBD epitope determines neutralization breadth of pan-sarbecovirus antibodies with recurring YYDRxxG motifs.
保守的 RBD 表位中的一个关键残基决定了具有重复 YYDRxxG 基序的泛沙贝病毒抗体的中和广度
期刊:mBio
影响因子:4.7
doi:10.1128/mbio.00606-25
Stein Saskia C, Ssebyatika George, Benecke Tim, Ströh Luisa, Rajak Manoj K, Vollmer Benjamin, Menz Sarah, Waldmann Ja-Yun, Tipp Sarah N, Ochulor Okechukwu, Herold Elisabeth, Schwarzloh Britta, Mutschall Doris, Zischke Jasmin, Schneider Talia, Hinrichs Imke, Blasczyk Rainer, Kleine-Weber Hannah, Hoffmann Markus, Klein Florian, Kaiser Franziska K, Gonzalez-Hernandez Mariana, Armando Federico, Ciurkiewicz Malgorzata, Beythien Georg, Pöhlmann Stefan, Baumgärtner Wolfgang, Gruenewald Kay, Osterhaus Albert, Schulz Thomas F, Krey Thomas, Hansen Guido
