Steinebach Christian相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

A Facile Protocol for C(sp(2))-C(sp(3)) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands

一种用于功能化E3连接酶配体的C(sp(2))-C(sp(3))键形成反应的简便方案

期刊:ChemMedChem

影响因子:3.4

doi:10.1002/cmdc.202500929

Maksutova, Anita; Geiger, Thomas M; Cianni, Lorenzo; Pieńkowska, Dominika E; Gerhartz, Jan; Read, Lina; Bricelj, Aleša; Herrmann, Alexander; Nelles, Maurice Leon; Ng, Yuen Lam Dora; Hartmann, Marcus D; Krönke, Jan; Sosič, Izidor; Nowak, Radosław P; Gütschow, Michael; Steinebach, Christian

发表日期：2026

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Development and Characterization of the First Selective Class IIb Histone Deacetylase Degraders.

首个选择性 IIb 类组蛋白去乙酰化酶降解剂的开发和表征

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.5c00674

Zhai Shiyang, Honin Irina, SchÃ¤ker-HÃ¼bner Linda, Hanl Maria, Jacobi Lukas, Dressler Finn, PieÅkowska Dominika Ewa, KÃ¶nig Philipp, Gerhartz Jan, Voget Rabea, Bendas Gerd, GÃ¼tschow Michael, Meissner Felix, Burckhardt Bjoern B, Nowak RadosÅaw P, Steinebach Christian, Hansen Finn K

发表日期：2025

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OSMI-4-based PROTACs do not influence O-GlcNAc transferase and O-GlcNAcylation levels in cells

基于OSMI-4的PROTACs不影响细胞内O-GlcNAc转移酶和O-GlcNAc糖基化的水平

期刊:RSC Advances

影响因子:4.6

doi:10.1039/d5ra02801a

Bricelj, Aleša; Novak, Doroteja; Smrdel, Lara; Steinebach, Christian; Sosič, Izidor; Anderluh, Marko; Gobec, Martina

细胞生物学

发表日期：2025

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PROTAC-Mediated GSPT1 Degradation Impairs the Expression of Fusion Genes in Acute Myeloid Leukemia.

PROTAC介导的GSPT1降解会损害急性髓系白血病中融合基因的表达

影响因子:4.4

doi:10.3390/cancers17020211

Perzolli Alicia, Steinebach Christian, KrÃ¶nke Jan, GÃ¼tschow Michael, Zwaan C Michel, Barneh Farnaz, Heidenreich Olaf

发表日期：2025

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Revisiting the antiangiogenic mechanisms of fluorinated thalidomide derivatives

重新审视氟化沙利度胺衍生物的抗血管生成机制

期刊:Bioorganic & Medicinal Chemistry Letters

影响因子:2.2

doi:10.1016/j.bmcl.2024.129858

Sievers, Johannes; Voget, Rabea; Lu, Feiteng; Garchitorena, Kathleen M; Ng, Yuen Lam Dora; Chau, Cindy H; Steinebach, Christian; Figg, William D; Krönke, Jan; Gütschow, Michael

发表日期：2024

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Solubility Enhanced Formulation Approaches to Overcome Oral Delivery Obstacles of PROTACs

通过提高溶解度来克服PROTACs口服给药障碍的制剂方法

期刊:Pharmaceutics

影响因子:5.5

doi:10.3390/pharmaceutics15010156

Pöstges, Florian; Kayser, Kevin; Appelhaus, Jan; Monschke, Marius; Gütschow, Michael; Steinebach, Christian; Wagner, Karl G

发表日期：2023

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Accessing three-branched high-affinity cereblon ligands for molecular glue and protein degrader design

获取用于分子胶和蛋白质降解剂设计的三分支高亲和力cereblon配体

期刊:RSC Chemical Biology

影响因子:3.1

doi:10.1039/d2cb00223j

Kuchta, Robert; Heim, Christopher; Herrmann, Alexander; Maiwald, Samuel; Ng, Yuen Lam Dora; Sosič, Izidor; Keuler, Tim; Krönke, Jan; Gütschow, Michael; Hartmann, Marcus D; Steinebach, Christian

发表日期：2023

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E3 Ligase Ligands in Successful PROTACs: An Overview of Syntheses and Linker Attachment Points

PROTAC 成功应用的 E3 连接酶配体：合成及连接基团连接点概述

期刊:Frontiers in Chemistry

影响因子:4.2

doi:10.3389/fchem.2021.707317

Bricelj, Aleša; Steinebach, Christian; Kuchta, Robert; Gütschow, Michael; Sosič, Izidor

发表日期：2021

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Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs

新型沙利度胺类似物的抗血管生成活性及计算机模拟Cereblon结合分析

期刊:Molecules

影响因子:4.6

doi:10.3390/molecules25235683

Peach, Megan L; Beedie, Shaunna L; Chau, Cindy H; Collins, Matthew K; Markolovic, Suzana; Luo, Weiming; Tweedie, David; Steinebach, Christian; Greig, Nigel H; Gütschow, Michael; Vargesson, Neil; Nicklaus, Marc C; Figg, William D

发表日期：2020

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A MedChem toolbox for cereblon-directed PROTACs

用于 cereblon 靶向 PROTAC 的药物化学工具箱

期刊:Medchemcomm

doi:10.1039/c9md00185a

Steinebach, Christian; Sosič, Izidor; Lindner, Stefanie; Bricelj, Aleša; Kohl, Franziska; Ng, Yuen Lam Dora; Monschke, Marius; Wagner, Karl G; Krönke, Jan; Gütschow, Michael

发表日期：2019

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