日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Anti-CTLA-4 synergizes with dendritic cell-targeted vaccine to promote IL-3-dependent CD4(+) effector T cell infiltration into murine pancreatic tumors

抗CTLA-4与靶向树突状细胞的疫苗协同作用,促进IL-3依赖性CD4(+)效应T细胞浸润到小鼠胰腺肿瘤中。

Zaidi, Neeha; Quezada, Sergio A; Kuroiwa, Janelle M Y; Zhang, Li; Jaffee, Elizabeth M; Steinman, Ralph M; Wang, Bei

Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance

小鼠朗格汉斯细胞表达朗格林(Langerin)的真皮树突状细胞可启动CD8+ T细胞,而朗格汉斯细胞则诱导交叉耐受。

Flacher, Vincent; Tripp, Christoph H; Mairhofer, David G; Steinman, Ralph M; Stoitzner, Patrizia; Idoyaga, Juliana; Romani, Nikolaus

Direct type I IFN but not MDA5/TLR3 activation of dendritic cells is required for maturation and metabolic shift to glycolysis after poly IC stimulation

直接激活I型干扰素(而非MDA5/TLR3)是树突状细胞成熟和在聚肌胞苷酸(poly IC)刺激后代谢向糖酵解转变所必需的。

Pantel, Austin; Teixeira, Angela; Haddad, Elias; Wood, Elizabeth G; Steinman, Ralph M; Longhi, M Paula

Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells

Flt3L依赖性有助于确定小鼠皮肤树突状细胞中一个尚未表征的亚群

Mollah, Shamim A; Dobrin, Joseph S; Feder, Rachel E; Tse, Sze-Wah; Matos, Ines G; Cheong, Cheolho; Steinman, Ralph M; Anandasabapathy, Niroshana

CD141+ dendritic cells produce prominent amounts of IFN-α after dsRNA recognition and can be targeted via DEC-205 in humanized mice

CD141+树突状细胞在识别dsRNA后产生大量IFN-α,并且在人源化小鼠中可被DEC-205靶向治疗。

Meixlsperger, Sonja; Leung, Carol S; Rämer, Patrick C; Pack, Maggi; Vanoaica, Liliana D; Breton, Gaëlle; Pascolo, Steve; Salazar, Andres M; Dzionek, Andrzej; Schmitz, Jürgen; Steinman, Ralph M; Münz, Christian

A new synthetic TLR4 agonist, GLA, allows dendritic cells targeted with antigen to elicit Th1 T-cell immunity in vivo

新型合成TLR4激动剂GLA可使靶向抗原的树突状细胞在体内诱导Th1 T细胞免疫反应。

Pantel, Austin; Cheong, Cheolho; Dandamudi, Durga; Shrestha, Elina; Mehandru, Saurabh; Brane, Luke; Ruane, Darren; Teixeira, Angela; Bozzacco, Leonia; Steinman, Ralph M; Longhi, M Paula

Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV gag p24 protein

从 HIV gag p24 蛋白中鉴定树突状细胞加工的 CD4+ T 细胞表位的策略

Bozzacco, Leonia; Yu, Haiqiang; Dengjel, Jörn; Trumpfheller, Christine; Zebroski, Henry A 3rd; Zhang, Nawei; Küttner, Victoria; Ueberheide, Beatrix M; Deng, Haiteng; Chait, Brian T; Steinman, Ralph M; Mojsov, Svetlana; Fenyö, David

PE-Cy5.5 conjugates bind to the cells expressing mouse DEC205/CD205

PE-Cy5.5 缀合物与表达小鼠 DEC205/CD205 的细胞结合

Park, Chae Gyu; Rodriguez, Anthony; Steinman, Ralph M

Generation of anti-human DEC205/CD205 monoclonal antibodies that recognize epitopes conserved in different mammals

制备能够识别不同哺乳动物中保守表位的抗人DEC205/CD205单克隆抗体

Park, Chae Gyu; Rodriguez, Anthony; Ueta, Hisashi; Lee, Haekyung; Pack, Maggi; Matsuno, Kenjiro; Steinman, Ralph M

Epidermal Langerhans cells rapidly capture and present antigens from C-type lectin-targeting antibodies deposited in the dermis

表皮朗格汉斯细胞能够快速捕获并呈递沉积在真皮中的C型凝集素靶向抗体的抗原。

Flacher, Vincent; Tripp, Christoph H; Stoitzner, Patrizia; Haid, Bernhard; Ebner, Susanne; Del Frari, Barbara; Koch, Franz; Park, Chae Gyu; Steinman, Ralph M; Idoyaga, Juliana; Romani, Nikolaus