Structural toggle in the RNaseH domain of Prp8 helps balance splicing fidelity and catalytic efficiency
Prp8 的 RNaseH 结构域中的结构开关有助于平衡剪接保真度和催化效率。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1701462114
Mayerle, Megan; Raghavan, Madhura; Ledoux, Sarah; Price, Argenta; Stepankiw, Nicholas; Hadjivassiliou, Haralambos; Moehle, Erica A; Mendoza, Senén D; Pleiss, Jeffrey A; Guthrie, Christine; Abelson, John