日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Plasmin activity promotes amyloid deposition in a transgenic model of human transthyretin amyloidosis

纤溶酶活性促进人类转甲状腺素蛋白淀粉样变性转基因模型中的淀粉样蛋白沉积

Ivana Slamova, Rozita Adib, Stephan Ellmerich, Michal R Golos, Janet A Gilbertson, Nicola Botcher, Diana Canetti, Graham W Taylor, Nigel Rendell, Glenys A Tennent, Guglielmo Verona, Riccardo Porcari, P Patrizia Mangione, Julian D Gillmore, Mark B Pepys, Vittorio Bellotti, Philip N Hawkins, Raya Al-S

A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo

特异性纳米抗体可在体外预防 D76N β2-微球蛋白的淀粉样变性,并在体内改变其组织分布

Sara Raimondi, Riccardo Porcari, P Patrizia Mangione, Guglielmo Verona, Julien Marcoux, Sofia Giorgetti, Graham W Taylor, Stephan Ellmerich, Maurizio Ballico, Stefano Zanini, Els Pardon, Raya Al-Shawi, J Paul Simons, Alessandra Corazza, Federico Fogolari, Manuela Leri, Massimo Stefani, Monica Buccia

Amyloid persistence in decellularized liver: biochemical and histopathological characterization

脱细胞肝脏中淀粉样蛋白的持久性:生化和组织病理学特征

Giuseppe Mazza, J Paul Simons, Raya Al-Shawi, Stephan Ellmerich, Luca Urbani, Sofia Giorgetti, Graham W Taylor, Janet A Gilbertson, Andrew R Hall, Walid Al-Akkad, Dipok Dhar, Philip N Hawkins, Paolo De Coppi, Massimo Pinzani, Vittorio Bellotti, P Patrizia Mangione

Exon skipping of hepatic APOB pre-mRNA with splice-switching oligonucleotides reduces LDL cholesterol in vivo

利用剪接转换寡核苷酸进行肝 APOB 前 mRNA 外显子跳跃可降低体内 LDL 胆固醇

Petra Disterer, Raya Al-Shawi, Stephan Ellmerich, Simon N Waddington, James S Owen, J Paul Simons, Bernard Khoo

Isolation and characterization of pharmaceutical grade human pentraxins, serum amyloid P component and C-reactive protein, for clinical use

分离和表征用于临床的药物级人正五聚蛋白、血清淀粉样蛋白 P 成分和 C 反应蛋白

Mark B Pepys, J Ruth Gallimore, Joanne Lloyd, Zhanhong Li, David Graham, Graham W Taylor, Stephan Ellmerich, Palma P Mangione, Glenys A Tennent, Winston L Hutchinson, David J Millar, Gary Bennett, John More, David Evans, Yogesh Mistry, Stephen Poole, Philip N Hawkins