Stephan N Witt相关文献与解析，生知库 | 链接生命科学的每一步

Moriah R Arnold, Gabriel M Cohn, Kezia Catharina Oxe, Somarr N Elliott, Cynthia Moore, Peter V Laraia, Sahar Shekoohi, Dillon Brownell, Charles K Meshul, Stephan N Witt, Dorthe H Larsen, Vivek K Unni

肿瘤

黑色素瘤

FCM

Knocking out alpha-synuclein in melanoma cells downregulates L1CAM and decreases motility

敲除黑色素瘤细胞中的 α-突触核蛋白会下调 L1CAM 并降低运动能力

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-023-36451-3

Nithya Gajendran #, Santhanasabapathy Rajasekaran #, Stephan N Witt

Loss of tumor suppressor menin expression in high grade cholangiocarcinomas

高级别胆管癌中肿瘤抑制因子menin表达的丧失

期刊:BMC Research Notes

影响因子:1.6

doi:10.1186/s13104-023-06282-6

Terry C Lairmore, Jehan Abdulsattar, Arrigo De Benedetti, Runhua Shi, Shile Huang, Md Imtiaz Khalil, Stephan N Witt

α-synuclein inhibits Snx3-retromer retrograde trafficking of the conserved membrane-bound proprotein convertase Kex2 in the secretory pathway of Saccharomyces cerevisiae

α-突触核蛋白抑制酿酒酵母分泌途径中保守的膜结合蛋白前体转化酶 Kex2 的 Snx3-retromer 逆向运输

期刊:Human Molecular Genetics

影响因子:3.1

doi:10.1093/hmg/ddab284

Santhanasabapathy Rajasekaran, Patricia P Peterson, Zhengchang Liu, Lucy C Robinson, Stephan N Witt

微生物学

发表日期：2022

文献求助收藏

α-synuclein and phosphoinositide-binding proteins: α-synuclein inhibits the association of PX- but not FYVE-containing proteins with vesicles in vivo

α-突触核蛋白和磷酸肌醇结合蛋白：α-突触核蛋白抑制体内含 PX 而非 FYVE 的蛋白质与囊泡的结合

期刊:Biochemical and Biophysical Research Communications

影响因子:2.5

doi:10.1016/j.bbrc.2022.01.101

Santhanasabapathy Rajasekaran, Dhaval Patel, Stephan N Witt

囊泡

发表日期：2022

文献求助收藏

Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth

敲除黑色素瘤细胞中的 α-突触核蛋白会导致细胞铁代谢失调并抑制肿瘤生长

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-021-84443-y

Sahar Shekoohi, Santhanasabapathy Rajasekaran, Dhaval Patel, Shu Yang, Wang Liu, Shile Huang, Xiuping Yu, Stephan N Witt

Reactivation of Aggregated Proteins by the ClpB/DnaK Bi-Chaperone System

ClpB/DnaK 双分子伴侣系统重新激活聚集蛋白

期刊:Current Protocols in Protein Science

影响因子:

doi:10.1002/0471140864.ps2810s83

Michal Zolkiewski, Liudmila S Chesnokova, Stephan N Witt

发表日期：2016

文献求助收藏

Phosphatidylethanolamine deficiency disrupts α-synuclein homeostasis in yeast and worm models of Parkinson disease

磷脂酰乙醇胺缺乏会破坏帕金森病酵母和蠕虫模型中的 α-突触核蛋白稳态

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:

doi:10.1073/pnas.1411694111

Shaoxiao Wang, Siyuan Zhang, Liang-Chun Liou, Qun Ren, Zhaojie Zhang, Guy A Caldwell, Kim A Caldwell, Stephan N Witt

A peroxisome biogenesis deficiency prevents the binding of alpha-synuclein to lipid droplets in lipid-loaded yeast

过氧化物酶体生物合成缺陷阻止了 α-突触核蛋白与载脂酵母中的脂滴结合

期刊:Biochemical and Biophysical Research Communications

影响因子:2.5

doi:10.1016/j.bbrc.2013.07.100

Shaoxiao Wang, Patrick J Horn, Liang-Chun Liou, Martin I Muggeridge, Zhaojie Zhang, Kent D Chapman, Stephan N Witt

微生物学

发表日期：2013

文献求助收藏

Isocitrate dehydrogenase 1 is downregulated during early skin tumorigenesis which can be inhibited by overexpression of manganese superoxide dismutase

异柠檬酸脱氢酶 1 在早期皮肤肿瘤发生过程中下调，可通过过表达锰超氧化物歧化酶来抑制

期刊:Cancer Science

影响因子:4.5

doi:10.1111/j.1349-7006.2012.02317.x

Delira Robbins, Jennifer A Wittwer, Sarah Codarin, Magdalena L Circu, Tak Yee Aw, Ting-Ting Huang, Holly Van Remmen, Arlan Richardson, David B Wang, Stephan N Witt, Ronald L Klein, Yunfeng Zhao

Alpha-synuclein regulates nucleolar DNA double-strand break repair in melanoma

α-突触核蛋白调节黑色素瘤中的核仁 DNA 双链断裂修复

Knocking out alpha-synuclein in melanoma cells downregulates L1CAM and decreases motility

敲除黑色素瘤细胞中的 α-突触核蛋白会下调 L1CAM 并降低运动能力

Loss of tumor suppressor menin expression in high grade cholangiocarcinomas

高级别胆管癌中肿瘤抑制因子menin表达的丧失

α-synuclein inhibits Snx3-retromer retrograde trafficking of the conserved membrane-bound proprotein convertase Kex2 in the secretory pathway of Saccharomyces cerevisiae

α-突触核蛋白抑制酿酒酵母分泌途径中保守的膜结合蛋白前体转化酶 Kex2 的 Snx3-retromer 逆向运输

α-synuclein and phosphoinositide-binding proteins: α-synuclein inhibits the association of PX- but not FYVE-containing proteins with vesicles in vivo

α-突触核蛋白和磷酸肌醇结合蛋白：α-突触核蛋白抑制体内含 PX 而非 FYVE 的蛋白质与囊泡的结合

Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth

敲除黑色素瘤细胞中的 α-突触核蛋白会导致细胞铁代谢失调并抑制肿瘤生长

Reactivation of Aggregated Proteins by the ClpB/DnaK Bi-Chaperone System

ClpB/DnaK 双分子伴侣系统重新激活聚集蛋白

Phosphatidylethanolamine deficiency disrupts α-synuclein homeostasis in yeast and worm models of Parkinson disease

磷脂酰乙醇胺缺乏会破坏帕金森病酵母和蠕虫模型中的 α-突触核蛋白稳态

A peroxisome biogenesis deficiency prevents the binding of alpha-synuclein to lipid droplets in lipid-loaded yeast

过氧化物酶体生物合成缺陷阻止了 α-突触核蛋白与载脂酵母中的脂滴结合

Isocitrate dehydrogenase 1 is downregulated during early skin tumorigenesis which can be inhibited by overexpression of manganese superoxide dismutase

异柠檬酸脱氢酶 1 在早期皮肤肿瘤发生过程中下调，可通过过表达锰超氧化物歧化酶来抑制