p27 controls Ragulator and mTOR activity in amino acid-deprived cells to regulate the autophagy-lysosomal pathway and coordinate cell cycle and cell growth
p27 控制氨基酸缺乏细胞中的 Ragulator 和 mTOR 活性,从而调节自噬-溶酶体途径并协调细胞周期和细胞生长
期刊:Nature Cell Biology
影响因子:17.3
doi:10.1038/s41556-020-0554-4
Ada Nowosad, Pauline Jeannot, Caroline Callot, Justine Creff, Renaud Thierry Perchey, Carine Joffre, Patrice Codogno, Stephane Manenti, Arnaud Besson
信号转导
细胞生物学
其它细胞
Autophagy
mTOR