Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells
Roquin 抑制 PI3K-mTOR 信号通路以抑制 T 辅助细胞分化和 Treg 向 Tfr 细胞的转化
期刊:Immunity
影响因子:25.5
doi:10.1016/j.immuni.2017.11.008
Katharina Essig, Desheng Hu, Joao C Guimaraes, Dominik Alterauge, Stephanie Edelmann, Timsse Raj, Jan Kranich, Gesine Behrens, Alexander Heiseke, Stefan Floess, Juliane Klein, Andreas Maiser, Susan Marschall, Martin Hrabĕ de Angelis, Heinrich Leonhardt, Cornelis F Calkhoven, Elfriede Noessner, Thoma
信号转导
T细胞
WB
PI3K/Akt
T Cell Receptor
mTOR
