Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling
SETD6 对 NF-κB 亚基 RelA 的赖氨酸甲基化与染色质上组蛋白甲基转移酶 GLP 的活性相结合，从而对 NF-κB 信号传导产生强直抑制
期刊:Nature Immunology
影响因子:27.7
doi:10.1038/ni.1968
Dan Levy, Alex J Kuo, Yanqi Chang, Uwe Schaefer, Christopher Kitson, Peggie Cheung, Alexsandra Espejo, Barry M Zee, Chih Long Liu, Stephanie Tangsombatvisit, Ruth I Tennen, Andrew Y Kuo, Song Tanjing, Regina Cheung, Katrin F Chua, Paul J Utz, Xiaobing Shi, Rab K Prinjha, Kevin Lee, Benjamin A Garcia
